San Diego Padres vs New York Yankees Odds

The Padres will play the Yankees on Wednesday, May 7th, 2025. Your timezone's first pitch time is 7:05 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The San Diego Padres have a 98.00 power ranking. The power ranking for the New York Yankees is 94.67.
  • Visiting San Diego Padres - The San Diego Padres have a 9-7 record as a visiting team, ranking them 4th Overall for visiting team wins.
  • Home New York Yankees - The New York Yankees have a 11-8 record as a home team. They rank 5th for home team wins in the Overall standings.
  • Runs Scored - The San Diego Padres currently stand 16th (137) Overall, with the New York Yankees ranking 2nd (190) for runs scored.
  • Runs Allowed - The San Diego Padres are 27th (98) Overall for runs allowed. The New York Yankees stand 19th (139) for runs allowed.
  • Team Streaks - The San Diego Padres have won their last 6 games. Meanwhile, the New York Yankees have lost their last 3 games.
  • Team Records - The San Diego Padres have a 23-11 Overall record (0.5 GB National West Division), with the New York Yankees possessing a 19-16 Overall standing (0.0 GB American East Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Arrr, the Padres be sailing into hostile territory to face the Yankees...

With a record like ours, those scallywags better be ready for a fight...

SportsBetting3.com has the odds, so place yer bets and let the plunderin' begin!

Best Padres at Yankees Odds


Best Moneyline Betting Odds
Underdog

San Diego Padres
Favorite

New York Yankees
The New York Yankees are the -182 moneyline favorite. Risk $182 to win $100 on the New York Yankees at BetRivers. The San Diego Padres are the +155 underdog at BetRivers. Risk $100 to win $155 on the San Diego Padres. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 8 runs. Risk $107 to win $100. BetMGM has the best under line of 8 runs. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

San Diego Padres
Favorite

New York Yankees
The New York Yankees have a -1.5 +118 run line at BetRivers PA. They are the run line favorite in this matchup. The San Diego Padres have a +1.5 -135 run line at BetMGM PA. The San Diego Padres are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the San Diego Padres vs New York Yankees MLB game on Wednesday, May 7th, 2025?

The New York Yankees are the -182 moneyline favorite at BetRivers and the San Diego Padres are the +155 moneyline underdog at BetRivers.

What is the over-under total line for the San Diego Padres vs New York Yankees MLB game on Wednesday, May 7th, 2025?

The best over line is 8 -107 runs at BetRivers, which means you risk $107 to win $100 betting the over. The best under line is 8 -110 runs at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the run line for the San Diego Padres vs New York Yankees MLB game on Wednesday, May 7th, 2025?

The New York Yankees are -1.5 +118 run line favorites at BetRivers, while the San Diego Padres are +1.5 -135 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Padres
Yankees
5/07/25 7:05pm EDT
+150-185
Bet $100 at BetMGM Pennsylvania
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Possible Moneyline Outcomes
  • San Diego Padres bettors risk $100 to win $150 at +150 odds. The implied probability for San Diego Padres is 40%.
  • New York Yankees bettors risk $100 to win $54.05 at -185 odds. The implied probability for New York Yankees is 64.91%.

San Diego Padres at New York Yankees Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Padres
Yankees
First Team to Score
5/07/25 7:05pm EDT
-120-105Bet
Padres
Yankees
Tie
1st Inning Winner
5/07/25 7:05pm EDT
+350+260-140Bet
Padres
Yankees
Tie
First 3 Innings Winner
5/07/25 7:05pm EDT
+180+110+280Bet
Padres
Yankees
To Extra Innings
5/07/25 7:05pm EDT
Yes +750No -1200Bet
BetMGM Sports Betting BetMGM
Padres
Yankees
1st Team to Score Will Win
5/07/25 7:05pm EDT
Yes -250No +190Bet
Yankees
Total Runs
SDG at NYY
5/07/25 7:05pm EDT
4.5 o +1004.5 u -130Bet
Padres
Total Runs
SDG at NYY
5/07/25 7:05pm EDT
3.5 o -1023.5 u -130Bet
Dylan Cease
Strikeouts Thrown
SDG at NYY
5/07/25 7:05pm EDT
5.5 o -1355.5 u +105Bet
BetMGM Sports Betting BetMGM
Max Fried
Strikeouts Thrown
SDG at NYY
5/07/25 7:05pm EDT
5.5 o +1305.5 u -175Bet

San Diego Padres & New York Yankees Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

San Diego Padres World Series Odds
2025 San Diego Padres World Series Odds

Team
BetMGM Sports Betting BetMGM BetRivers Sports Betting BetRivers
Padres
+3500
Bet
+2500
Bet
New York Yankees World Series Odds
2025 New York Yankees World Series Odds

Team
BetMGM Sports Betting BetMGM BetRivers Sports Betting BetRivers
Yankees
+750
Bet
+700
Bet

San Diego Padres & New York Yankees Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - San Diego Padres, New York Yankees
Team W L Pct GB Home Away RS RA Diff Strk L10
New York Yankees53430.552+5.530-1923-24501390+111L25-5
San Diego Padres52440.542+6.531-1821-26383376+7L16-4

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Diego Padres vs New York Yankees MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, May 7th, 2025 at 7:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the San Diego Padres vs New York Yankees Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Diego Padres vs New York Yankees Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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