The Cardinals will play the Orioles on Wednesday, May 28th, 2025. Your timezone's first pitch time is 6:35 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
| Bonus | |
|---|---|
 #1 BetMGMREVIEW | New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966 |
Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - As the 2025 season continues, the St. Louis Cardinals possess a 95.33 SportsBetting3.com power ranking. The Baltimore Orioles now have a 86.33 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
- Visiting St. Louis Cardinals - The St. Louis Cardinals head into this matchup with a 11-16 record as a visiting team. This standing ranks them 7th Overall for visiting team wins.
- Home Baltimore Orioles - The Baltimore Orioles will throw the first pitch possessing a 9-15 home team record. That puts them 10th for home team wins in the Overall MLB standings.
- Runs Scored - St. Louis Cardinals batters have produced 256 runs, ranking them 8th Overall, with the Baltimore Orioles ranking 23rd (205) for runs scored.
- Runs Allowed - St. Louis Cardinals pitchers and fielders have allowed 216 runs, ranking them 17th Overall for runs allowed. Meanwhile, the Baltimore Orioles now rank 3rd Overall, allowing 297 runs.
- Team Streaks - The St. Louis Cardinals lost their last game. Their opponent, the Baltimore Orioles have won their last 3 games.
- Team Records - Let's review each team's records. The St. Louis Cardinals have a 30-24 Overall record (3.0 GB National Central Division), with the Baltimore Orioles notching a 19-34 Overall standing (14.0 GB American East Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye scallywags! The St. Louis Cardinals be takin' on the Baltimore Orioles...
The Cardinals be comin' in with a record of 30-24, ready to plunder...
The Orioles be sittin' at a dismal 19-34, ripe for the takin'...
Bet on MLB baseball at legal US sportsbooks, me hearties, and watch the battle unfold...
Check out this game's prop bets below, and see who be walkin' the plank...
Both teams be fightin' for glory on the diamond, so stay tuned...
Review each team's standin' at the bottom of the page, and may the best team win!
Best Cardinals at Orioles Odds
| Underdog St. Louis Cardinals | Favorite Baltimore Orioles |
|---|---|
| Over | Under |
|---|---|
| Underdog Baltimore Orioles | Favorite St. Louis Cardinals |
|---|---|
Matchup Odds FAQs
The Baltimore Orioles are the -120 moneyline favorite at BetMGM and the St. Louis Cardinals are the +100 moneyline underdog at BetMGM.
The best over line is 7.5 -120 runs at BetMGM, which means you risk $120 to win $100 betting the over. The best under line is 7.5 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.
The St. Louis Cardinals are -1.5 +170 run line favorites at BetMGM, while the Baltimore Orioles are +1.5 -210 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Cardinals
Orioles
5/28/25 6:35pm EDT | +100-120 |
- St. Louis Cardinals bettors risk $100 to win $100 at +100 odds. The implied probability for St. Louis Cardinals is 50%.
- Baltimore Orioles bettors risk $100 to win $83.33 at -120 odds. The implied probability for Baltimore Orioles is 54.55%.
St. Louis Cardinals at Baltimore Orioles Prop Bets
| BetMGM Bet |
|
|---|---|
Cardinals
Orioles
First Team to Score
5/28/25 6:35pm EDT | -155+118Bet |
Cardinals
Orioles
Tie
1st Inning Winner
5/28/25 6:35pm EDT | +300+310-140Bet |
Cardinals
Orioles
Tie
First 3 Innings Winner
5/28/25 6:35pm EDT | +145+140+270Bet |
Cardinals
Orioles
To Extra Innings
5/28/25 6:35pm EDT | Yes +700No -1100Bet |
| BetMGM | |
Cardinals
Orioles
1st Team to Score Will Win
5/28/25 6:35pm EDT | Yes -250No +190Bet |
Orioles
Total Runs
STL at BAL 5/28/25 6:35pm EDT | 3.5 o -1303.5 u +100Bet |
Cardinals
Total Runs
STL at BAL 5/28/25 6:35pm EDT | 3.5 o -1253.5 u -105Bet |
Cade Povich
Strikeouts Thrown
STL at BAL 5/28/25 6:35pm EDT | 4.5 o -1404.5 u +105Bet |
| BetMGM | |
Miles Mikolas
Strikeouts Thrown
STL at BAL 5/28/25 6:35pm EDT | 3.5 o -1103.5 u -120Bet |
St. Louis Cardinals & Baltimore Orioles Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
St. Louis Cardinals World Series Odds|
Team | BetMGM |
|---|---|
| Cardinals | +6600 Bet |
|
Team | BetMGM |
|---|---|
| Orioles | +20000 Bet |
St. Louis Cardinals & Baltimore Orioles Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| St. Louis Cardinals | 30 | 24 | 0.556 | +5.0 | 19-8 | 11-16 | 256 | 216 | +40 | L1 | 6-4 |
| Baltimore Orioles | 19 | 34 | 0.358 | +15.5 | 9-15 | 10-19 | 205 | 297 | -92 | W3 | 4-6 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the St. Louis Cardinals vs Baltimore Orioles MLB Game
-
Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, May 28th, 2025 at 6:35 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
-
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
-
Tap to the sportsbook's MLB page, look for the St. Louis Cardinals vs Baltimore Orioles Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the St. Louis Cardinals vs Baltimore Orioles Game.
-
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other May 28, 2025 MLB Games
- Boston Red Sox vs Milwaukee Brewers - 5/28/25 1:10pm EDT
- Chicago White Sox vs New York Mets - 5/28/25 1:10pm EDT
- Los Angeles Dodgers vs Cleveland Guardians - 5/28/25 1:10pm EDT
- Minnesota Twins vs Tampa Bay Rays - 5/28/25 1:10pm EDT
- San Francisco Giants vs Detroit Tigers - 5/28/25 1:10pm EDT
- Oakland Athletics vs Houston Astros - 5/28/25 2:10pm EDT
- Pittsburgh Pirates vs Arizona Diamondbacks - 5/28/25 3:40pm EDT
- Miami Marlins vs San Diego Padres - 5/28/25 4:10pm EDT
- Atlanta Braves vs Philadelphia Phillies - 5/28/25 6:45pm EDT
- Cincinnati Reds vs Kansas City Royals - 5/28/25 7:40pm EDT
- Colorado Rockies vs Chicago Cubs - 5/28/25 8:05pm EDT
- Toronto Blue Jays vs Texas Rangers - 5/28/25 8:08pm EDT
- New York Yankees vs Los Angeles Angels - 5/28/25 9:38pm EDT
- Washington Nationals vs Seattle Mariners - 5/28/25 9:40pm EDT