The Cardinals will play the Hokies on Saturday, November 1st, 2025. The matchup takes place at Lane Stadium. Watch this exciting Week 10 matchup at 3:00 pm EDT. Check local listings for coverage on The CW Network.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
| Bonus | |
|---|---|
 #1 BetMGMREVIEW | New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966 |
Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
It's now the back half of the 2025 college football season, as we begin looking towards the annual bowl games and college football playoffs. Week 10 action features a matchup between Louisville and Virginia Tech, kicking off at Lane Stadium on Saturday, November 1st, 2025. Have a look at the following season performance stats to better handicap this game.
- SportsBetting3.com Power Rankings - Louisville has a 96.33 conference power ranking for the 2025 season. The conference power ranking for Virginia Tech is 91.67.
- Away Louisville - As Week 10 looms, Louisville currently has a 2-0 record as an away team for the 2025 regular season. This ranks them 2nd in the ACC Conference for away team wins. Remember that a team's overall record and schedule strength will affect whether or not they make a bowl game or the playoffs.
- Home Virginia Tech - Virginia Tech has a 2-3 record as a home team as they approach Week 10. They currently rank 4th in the ACC Conference for home team wins. Continue monitoring their performance to see if they have a shot at a postseason bowl game or playoff berth.
- Points Scored - For the 2025 season, Louisville ranks 7th (242) in the ACC Conference, with Virginia Tech currently ranking 11th (203) for points scored in the ACC Conference.
- Points Against - Louisville stands 13th (150) in the ACC Conference for points scored by opponents in the 2025 college football season. Virginia Tech sits at 3rd (239) in the ACC Conference for points against them heading into Week 10 of the 2025 season.
- Team Records - Louisville has a 6-1 overall record for the 2025 regular season, with Virginia Tech currently 3-5 for the 2025 college football regular season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Get ready for a wild showdown as Louisville faces off against Virginia Tech!
On Saturday, November 1st, the Cardinals will take on the Hokies at Lane Stadium.
Louisville comes in hot with a Power Ranking of 96.33, while Virginia Tech trails at 91.67.
The Cardinals boast a 6-1 record, while the Hokies are struggling at 3-5. Place a bet on this college football game at BetMGM or BetRivers and see this matchup's prop bets below. Compare each sportsbook's point spread, total, and moneyline.
Best Cardinals at Hokies Odds
| Underdog Virginia Tech | Favorite Louisville |
|---|---|
| Over | Under |
|---|---|
| Underdog Virginia Tech | Favorite Louisville |
|---|---|
Matchup Odds FAQs
Louisville is a -10.5 -105 point spread favorite at BetMGM, while Virginia Tech is a +10.5 -115 point spread underdog at BetMGM.
The best over line is 53.5 -105 points at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 53.5 -115 points at BetMGM, and that means you risk $115 to win $100 betting the under.
Louisville is a -400 moneyline favorite at BetMGM and Virginia Tech is a +310 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
Louisville
Virginia Tech
11/01/25 3:00pm EDT | -10.5 -105+10.5 -115 |
Underdog Virginia Tech - Virginia Tech bettors risk $100 to win $86.96 at -115 odds.
A +10.5 Virginia Tech underdog bet wins if they lose by 10 or fewer, tie, or win outright. Your bet loses if they lose by 11 or more.
Favorite Louisville - Louisville bettors risk $100 to win $95.24 at -105 odds.
A -10.5 Louisville favorite bet wins if they win by 11 or more. Your bet loses if they win by 10 or fewer, tie, or lose outright.
Louisville at Virginia Tech Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Louisville
Virginia Tech
No Touchdown
To Score 1st Touchdown
11/01/25 3:00pm EDT | -225+154+10000Bet |
Louisville
Virginia Tech
Game to Overtime
11/01/25 3:00pm EDT | Yes +1200No -10000Bet |
Louisville
Virginia Tech
Both Teams Score 10+
11/01/25 3:00pm EDT | Yes -800No +500Bet |
Louisville
Virginia Tech
Both Teams Score 20+
11/01/25 3:00pm EDT | Yes -118No -110Bet |
| BetMGM | |
Louisville
Virginia Tech
Both Teams Score 30+
11/01/25 3:00pm EDT | Yes +500No -800Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 10 | Louisville vs Virginia Tech Saturday, November 1st, 2025 | LOU 28, VT 16 Lane Stadium | Louisville by 12 |
| 2023 Week 10 | Virginia Tech vs Louisville Saturday, November 4th, 2023 | LOU 34, VT 3 Cardinal Stadium | Louisville by 31 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| Louisville | 4-4 | 0.500 | 8 | 4 | 362 | 253 | 5-3 | 3-1 | W1 |
| Virginia Tech | 2-6 | 0.250 | 3 | 9 | 257 | 362 | 2-5 | 1-3 | L4 |
Louisville & Virginia Tech Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Louisville Championship OddsNo NCAA College Football Championship TM Louisville YR: futures available
Virginia Tech Championship OddsNo NCAA College Football Championship TM Virginia Tech YR: futures available
Louisville & Virginia Tech Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Eastern Kentucky vs Louisville | LOU 51, EKU 17 Saturday, August 30th, 2025 |
| Week 2 | James Madison vs Louisville | LOU 28, JMU 14 Friday, September 5th, 2025 |
| Week 4 | Bowling Green vs Louisville | LOU 40, BGSU 17 Saturday, September 20th, 2025 |
| Week 5 | Louisville vs Pittsburgh | LOU 34, PITT 27 Saturday, September 27th, 2025 |
| Week 6 | Virginia vs Louisville | UVA 30, LOU 27 (OT) Saturday, October 4th, 2025 |
| Week 8 | Louisville vs Miami (FL) | LOU 24, MIA 21 Friday, October 17th, 2025 |
| Week 9 | Boston College vs Louisville | LOU 38, BC 24 Saturday, October 25th, 2025 |
| Week 10 | Louisville vs Virginia Tech | LOU 28, VT 16 Saturday, November 1st, 2025 |
| Week 11 | California vs Louisville | CAL 29, LOU 26 (OT) Saturday, November 8th, 2025 |
| Week 12 | Clemson vs Louisville | CLEM 20, LOU 19 Friday, November 14th, 2025 |
| Week 13 | Louisville vs SMU | SMU 38, LOU 6 Saturday, November 22nd, 2025 |
| Week 14 | Kentucky vs Louisville | LOU 41, UK 0 Saturday, November 29th, 2025 |
| Bowls | Toledo vs Louisville Bush's Boca Raton Bowl | Tuesday, December 23rd, 2025 2:00 pm EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Virginia Tech vs South Carolina | SC 24, VT 11 Sunday, August 31st, 2025 |
| Week 2 | Vanderbilt vs Virginia Tech | VAN 44, VT 20 Saturday, September 6th, 2025 |
| Week 3 | Old Dominion vs Virginia Tech | ODU 45, VT 26 Saturday, September 13th, 2025 |
| Week 4 | Wofford vs Virginia Tech | VT 38, WOF 6 Saturday, September 20th, 2025 |
| Week 5 | Virginia Tech vs NC State | VT 23, NCSU 21 Saturday, September 27th, 2025 |
| Week 6 | Wake Forest vs Virginia Tech | WAKE 30, VT 23 Saturday, October 4th, 2025 |
| Week 7 | Virginia Tech vs Georgia Tech | GT 35, VT 20 Saturday, October 11th, 2025 |
| Week 9 | California vs Virginia Tech | VT 42, CAL 34 (2OT) Friday, October 24th, 2025 |
| Week 10 | Louisville vs Virginia Tech | LOU 28, VT 16 Saturday, November 1st, 2025 |
| Week 12 | Virginia Tech vs Florida State | FSU 34, VT 14 Saturday, November 15th, 2025 |
| Week 13 | Miami (FL) vs Virginia Tech | MIA 34, VT 17 Saturday, November 22nd, 2025 |
| Week 14 | Virginia Tech vs Virginia | UVA 27, VT 7 Saturday, November 29th, 2025 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Louisville vs Virginia Tech College Football Game
-
Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 1st, 2025 at 3:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
-
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
-
Tap to the sportsbook's College Football page, look for the Louisville vs Virginia Tech Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Louisville vs Virginia Tech Game.
-
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other November 1, 2025 NCAAFB Games
- Penn State vs Ohio State
- Rutgers vs Illinois
- Long Island University vs Central Connecticut
- UAB vs UConn
- UCF vs Baylor
- West Virginia vs Houston
- Towson vs North Carolina A&T
- Columbia vs Yale
- Wagner vs St. Francis (PA)
- Georgetown vs Lehigh
- Miami (FL) vs SMU
- Buffalo vs Bowling Green
- Vanderbilt vs Texas
- Army vs Air Force
- Duke vs Clemson
- Navy vs North Texas
- Arizona State vs Iowa State
- Samford vs Wofford
- Mercer vs Furman
- Montana State vs Northern Colorado
- Fordham vs Richmond
- Morgan State vs South Carolina State
- East Carolina vs Temple
- North Dakota vs South Dakota
- VMI vs The Citadel
- Charleston Southern vs Southeast Missouri State
- Marist vs St. Thomas
- Dartmouth vs Harvard
- Indiana State vs South Dakota State
- Alcorn State vs Texas Southern
- Alabama State vs Prairie View A&M
- Alabama A&M vs Grambling State
- Montana vs Weber State
- Northern Iowa vs Illinois State
- Southern vs Arkansas-Pine Bluff
- UT-Martin vs Eastern Illinois
- New Mexico vs UNLV
- Notre Dame vs Boston College
- Pittsburgh vs Stanford
- Old Dominion vs Louisiana-Monroe
- New Mexico State vs Western Kentucky
- Fresno State vs Boise State
- Louisiana vs South Alabama
- Delaware vs Liberty
- Georgia vs Florida
- Texas Tech vs Kansas State
- Michigan State vs Minnesota
- Indiana vs Maryland
- Virginia vs California
- Oklahoma State vs Kansas
- Mississippi State vs Arkansas
- Central Michigan vs Western Michigan
- Eastern Kentucky vs Central Arkansas
- Southern Illinois vs Murray State
- Portland State vs Cal Poly
- Purdue vs Michigan
- Jackson State vs Florida A&M
- Northwestern State vs McNeese State
- Wyoming vs San Diego State
- UTRGV vs Stephen F. Austin
- Arizona vs Colorado
- South Carolina vs Ole Miss
- Washington State vs Oregon State
- Georgia Tech vs NC State
- USC vs Nebraska
- Kentucky vs Auburn
- Wake Forest vs Florida State
- Oklahoma vs Tennessee
- Arkansas State vs Troy
- Austin Peay vs Southern Utah
- Cincinnati vs Utah
- Hawaii vs San Jose State