Penn State vs Ohio State Football Odds

The Nittany Lions will play the Buckeyes on Saturday, November 1st, 2025. The matchup takes place at Ohio Stadium. Watch this exciting Week 10 matchup at 12:00 pm EDT.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

It's now the back half of the 2025 college football season, as we begin looking towards the annual bowl games and college football playoffs. Week 10 action features a matchup between Penn State and Ohio State, kicking off at Ohio Stadium on Saturday, November 1st, 2025. Have a look at the following season performance stats to better handicap this game.

  • SportsBetting3.com Power Rankings - Penn State has a 92.33 conference power ranking for the 2025 season. The conference power ranking for Ohio State is 98.67.
  • Away Penn State - As Week 10 looms, Penn State currently has a 0-2 record as an away team for the 2025 regular season. This ranks them 4th in the Big Ten Conference for away team wins. Remember that a team's overall record and schedule strength will affect whether or not they make a bowl game or the playoffs.
  • Home Ohio State - Ohio State has a 4-0 record as a home team as they approach Week 10. They currently rank 3rd in the Big Ten Conference for home team wins. Continue monitoring their performance to see if they have a shot at a postseason bowl game or playoff berth.
  • Points Scored - For the 2025 season, Penn State ranks 10th (238) in the Big Ten Conference, with Ohio State currently ranking 7th (255) for points scored in the Big Ten Conference.
  • Points Against - Penn State stands 12th (136) in the Big Ten Conference for points scored by opponents in the 2025 college football season. Ohio State sits at 18th (41) in the Big Ten Conference for points against them heading into Week 10 of the 2025 season.
  • Team Records - Penn State has a 3-4 overall record for the 2025 regular season, with Ohio State currently 7-0 for the 2025 college football regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for a wild showdown as Penn State faces Ohio State in Week 10!

The game will be held at Ohio Stadium, setting the stage for an epic battle.

Penn State is ranked 92.33 in the Power Rankings, while Ohio State sits at 98.67.

Penn State is 3-4, while Ohio State remains undefeated at 7-0. Place a bet on this college football game at BetMGM or BetRivers and see this matchup's prop bets below. Compare each sportsbook's point spread, total, and moneyline.

Best Nittany Lions at Buckeyes Odds


Best Point Spread Betting Odds
Underdog

Penn State
Favorite

Ohio State
Ohio State has a -18.5 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. Penn State has a +18.5 -105 point spread at BetMGM OH. Penn State is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 44.5 points. Risk $110 to win $100. BetMGM has the best under line of 44.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Penn State
Favorite

Ohio State
Ohio State is the -1200 moneyline favorite. Risk $1,200 to win $100 on Ohio State at BetMGM. Penn State is the +750 underdog at BetMGM. Risk $100 to win $750 on Penn State. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Penn State vs Ohio State College Football game on Saturday, November 1st, 2025?

Ohio State is a -18.5 -105 point spread favorite at BetMGM, while Penn State is a +18.5 -105 point spread underdog at BetMGM.

What is the over-under total line for the Penn State vs Ohio State College Football game on Saturday, November 1st, 2025?

The best over line is 44.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 44.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Penn State vs Ohio State College Football game on Saturday, November 1st, 2025?

Ohio State is a -1200 moneyline favorite at BetMGM and Penn State is a +750 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Penn State
Ohio State
11/01/25 12:00pm EDT
+18.5 -105-18.5 -105
Bet $100 at BetMGM Ohio
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Underdog Penn State - Penn State bettors risk $100 to win $95.24 at -105 odds.

A +18.5 Penn State underdog bet wins if they lose by 18 or fewer, tie, or win outright. Your bet loses if they lose by 19 or more.

Favorite Ohio State - Ohio State bettors risk $100 to win $95.24 at -105 odds.

A -18.5 Ohio State favorite bet wins if they win by 19 or more. Your bet loses if they win by 18 or fewer, tie, or lose outright.

Penn State at Ohio State Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Penn State
Ohio State
No Touchdown
To Score 1st Touchdown
11/01/25 12:00pm EDT
+270-450+10000Bet
Penn State
Ohio State
Game to Overtime
11/01/25 12:00pm EDT
Yes +2000No -10000Bet
Penn State
Ohio State
Both Teams Score 10+
11/01/25 12:00pm EDT
Yes -200No +154Bet
Penn State
Ohio State
Both Teams Score 20+
11/01/25 12:00pm EDT
Yes +310No -450Bet
BetMGM Sports Betting BetMGM
Penn State
Ohio State
Both Teams Score 30+
11/01/25 12:00pm EDT
Yes +1850No -10000Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2024
Week 10
Ohio State vs Penn State
Saturday, November 2nd, 2024
OSU 20, PSU 13
Beaver Stadium
Ohio State by 7
2023
Week 8
Penn State vs Ohio State
Saturday, October 21st, 2023
OSU 20, PSU 12
Ohio Stadium
Ohio State by 8
2022
Week 9
Ohio State vs Penn State
Saturday, October 29th, 2022
OSU 44, PSU 31
Beaver Stadium
Ohio State by 13
2021
Week 9
Penn State vs Ohio State
Saturday, October 30th, 2021
OSU 33, PSU 24
Ohio Stadium
Ohio State by 9

Team Standings

2025-2026 College Football Regular Season Standings - Penn State, Ohio State
Team Conf Conf% W L PF PA Home Away Strk
#1 Ohio State5-01.00080293555-03-0W8
Penn State0-50.000352521743-20-3L5

Penn State & Ohio State Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Penn State Championship Odds

No NCAA College Football Championship TM Penn State YR: futures available

Ohio State Championship Odds
2025-26 Ohio State NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Ohio State
+200
Bet

Penn State & Ohio State Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Penn State Games & Results
WeekMatchupDate & Result
Week 1Nevada vs
Penn State
PSU 46, NEV 11
Saturday, August 30th, 2025
Week 2FIU vs
Penn State
PSU 34, FIU 0
Saturday, September 6th, 2025
Week 3Villanova vs
Penn State
PSU 52, VILL 6
Saturday, September 13th, 2025
Week 5Oregon vs
Penn State
ORE 30, PSU 24 (2OT)
Saturday, September 27th, 2025
Week 6Penn State vs
UCLA
UCLA 42, PSU 37
Saturday, October 4th, 2025
Week 7Northwestern vs
Penn State
NU 22, PSU 21
Saturday, October 11th, 2025
Week 8Penn State vs
Iowa
IOWA 25, PSU 24
Saturday, October 18th, 2025
Week 10Penn State vs
Ohio State
Saturday, November 1st, 2025
12:00 am EDT
Week 11Indiana vs
Penn State
Saturday, November 8th, 2025
12:00 am EST
Week 12Penn State vs
Michigan State
Saturday, November 15th, 2025
12:00 am EST
Week 13Nebraska vs
Penn State
Saturday, November 22nd, 2025
12:00 am EST
Week 14Penn State vs
Rutgers
Saturday, November 29th, 2025
12:00 am EST


2025-26 Ohio State Games & Results
WeekMatchupDate & Result
Week 1Texas vs
Ohio State
OSU 14, TEX 7
Saturday, August 30th, 2025
Week 2Grambling State vs
Ohio State
OSU 70, GRAM 0
Saturday, September 6th, 2025
Week 3Ohio vs
Ohio State
OSU 37, OHIO 9
Saturday, September 13th, 2025
Week 5Ohio State vs
Washington
OSU 24, WASH 6
Saturday, September 27th, 2025
Week 6Minnesota vs
Ohio State
OSU 42, MINN 3
Saturday, October 4th, 2025
Week 7Ohio State vs
Illinois
OSU 34, ILL 16
Saturday, October 11th, 2025
Week 8Ohio State vs
Wisconsin
OSU 34, WIS 0
Saturday, October 18th, 2025
Week 10Penn State vs
Ohio State
Saturday, November 1st, 2025
12:00 am EDT
Week 11Ohio State vs
Purdue
Saturday, November 8th, 2025
12:00 am EST
Week 12UCLA vs
Ohio State
Saturday, November 15th, 2025
12:00 am EST
Week 13Rutgers vs
Ohio State
Saturday, November 22nd, 2025
12:00 am EST
Week 14Ohio State vs
Michigan
Saturday, November 29th, 2025
12:00 pm EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Penn State vs Ohio State College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 1st, 2025 at 12:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Penn State vs Ohio State Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Penn State vs Ohio State Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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