Louisville vs Wake Forest Football Odds

The Cardinals will play the Demon Deacons on Saturday, October 2nd, 2021. The matchup takes place at Truist Field. Watch this exciting Week 5 matchup at 12:30 pm EDT. Check local listings for coverage on ESPN3.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets. Read the following to understand point spread betting.

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College Football Odds and Outcomes Explained

Game

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9:23am EDT
TBD VA
VA Odds Pending
No VA Point Spread lines available for this game.

Louisville at Wake Forest Prop Bets

College Football Prop Bets
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Louisville
Wake Forest
10/02/21 12:30pm EDT
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Recent Meetings Since 2017

WeekGameResultMargin
2021
Week 5
Louisville vs Wake Forest
Saturday, October 2nd, 2021
WAKE 37, LOU 34
Truist Field
Wake Forest by 3
2020
Week 15
Wake Forest vs Louisville
Saturday, December 12th, 2020
LOU 45, WAKE 21
Cardinal Stadium
Louisville by 24
2019
Week 7
Louisville vs Wake Forest
Saturday, October 12th, 2019
LOU 62, WAKE 59
Truist Field
Louisville by 3
2018
Week 9
Wake Forest vs Louisville
Saturday, October 27th, 2018
WAKE 56, LOU 35
Cardinal Stadium
Wake Forest by 21
2017
Week 9
Louisville vs Wake Forest
Saturday, October 28th, 2017
WAKE 42, LOU 32
Truist Field
Wake Forest by 10

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Louisville Season Win Total
2022 College Football Louisville Season Win Total
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Louisville
2022 Season Win Total
Wake Forest Season Win Total
2022 College Football Wake Forest Season Win Total
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Wake Forest
2022 Season Win Total

College Football Championship Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.

Louisville Championship Odds
2023 Louisville NCAA College Football Championship Odds

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Wake Forest Championship Odds
2023 Wake Forest NCAA College Football Championship Odds

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Wake Forest

2021 Louisville Games & Results

WeekMatchupDate & Time
Week 1Louisville vs
Ole Miss
MISS 43, LOU 24
Monday, September 6th, 2021
Week 2Eastern Kentucky vs
Louisville
LOU 30, EKU 3
Saturday, September 11th, 2021
Week 3UCF vs
Louisville
LOU 42, UCF 35
Friday, September 17th, 2021
Week 4Louisville vs
Florida State
LOU 31, FSU 23
Saturday, September 25th, 2021
Week 5Louisville vs
Wake Forest
WAKE 37, LOU 34
Saturday, October 2nd, 2021
Week 6Virginia vs
Louisville
UVA 34, LOU 33
Saturday, October 9th, 2021
Week 8Boston College vs
Louisville
LOU 28, BC 14
Saturday, October 23rd, 2021
Week 9Louisville vs
NC State
NCST 28, LOU 13
Saturday, October 30th, 2021
Week 10Clemson vs
Louisville
CLEM 30, LOU 24
Saturday, November 6th, 2021
Week 11Syracuse vs
Louisville
LOU 41, SYR 3
Saturday, November 13th, 2021
Week 12Louisville vs
Duke
LOU 62, DUKE 22
Thursday, November 18th, 2021
Week 13Kentucky vs
Louisville
UK 52, LOU 21
Saturday, November 27th, 2021
BowlsAir Force vs
Louisville
Servpro First Responder Bowl
AFA 31, LOU 28
Tuesday, December 28th, 2021

2021 Wake Forest Games & Results

WeekMatchupDate & Time
Week 1Old Dominion vs
Wake Forest
WAKE 42, ODU 10
Friday, September 3rd, 2021
Week 2Norfolk State vs
Wake Forest
WAKE 41, NORF 16
Saturday, September 11th, 2021
Week 3Florida State vs
Wake Forest
WAKE 35, FSU 14
Saturday, September 18th, 2021
Week 4Wake Forest vs
Virginia
WAKE 37, UVA 17
Friday, September 24th, 2021
Week 5Louisville vs
Wake Forest
WAKE 37, LOU 34
Saturday, October 2nd, 2021
Week 6Wake Forest vs
Syracuse
WAKE 40, SYR 37 (OT)
Saturday, October 9th, 2021
Week 8Wake Forest vs
Army
WAKE 70, ARMY 56
Saturday, October 23rd, 2021
Week 9Duke vs
Wake Forest
WAKE 45, DUKE 7
Saturday, October 30th, 2021
Week 10Wake Forest vs
North Carolina
UNC 58, WAKE 55
Saturday, November 6th, 2021
Week 11NC State vs
Wake Forest
WAKE 45, NCST 42
Saturday, November 13th, 2021
Week 12Wake Forest vs
Clemson
CLEM 48, WAKE 27
Saturday, November 20th, 2021
Week 13Wake Forest vs
Boston College
WAKE 41, BC 10
Saturday, November 27th, 2021
Week 14Pittsburgh vs
Wake Forest
PITT 45, WAKE 21
Saturday, December 4th, 2021
BowlsWake Forest vs
Rutgers
Taxslayer Gator Bowl
WAKE 38, RUTG 10
Friday, December 31st, 2021

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