The Jayhawks will play the Cyclones on Saturday, November 22nd, 2025. The matchup takes place at Jack Trice Stadium. Watch this exciting Week 13 matchup at 12:00 pm EST. Check local listings for coverage on FS1.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
We're now in the home stretch of the 2025 college football season, with Kansas and Iowa State meeting at Jack Trice Stadium for a key late-season matchup on Saturday, November 22nd, 2025. The playoffs are fast approaching, along with the annual Bowl games that kick off in December. Here's an overview of some important 2025 performance data for each team.
- SportsBetting3.com Power Rankings - As we wrap up the 2025 regular season, Kansas has notched a 94.67 Big 12 Conference conference power ranking. On the other side of the gridiron, Iowa State has a 95.67 Big 12 Conference power ranking.
- Away Kansas - Looking at Week 13, Kansas heads into this matchup with a 1-3 record as an away team. This ranks them 5th in the Big 12 Conference for away team wins in 2025. Remember that a team's overall record and schedule strength will affect whether or not they make a December bowl game or qualify for the playoffs.
- Home Iowa State - Meanwhile, Iowa State has a 3-2 record as a home team for 2025. They currently rank 4th in the Big 12 Conference for home team wins. Let's see if they can add another win to their record when they battle Kansas on Saturday, November 22nd, 2025.
- Points Scored - Now late in the 2025 season, Kansas ranks 8th (302) in the Big 12 Conference, with Iowa State currently ranking 11th (271) for points scored in the Big 12 Conference.
- Points Against - Kansas currently stands 7th (252) in the Big 12 Conference for points scored by opponents in the 2025 college football season. Their opponent, Iowa State, ranks 12th (215) in the Big 12 Conference for points against them as the 2025 college football season comes to a close.
- Team Records - As we head into Week 13, Kansas has a 5-5 overall record for the 2025 regular season, with Iowa State possessing a 6-4 standing for the 2025 college football season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Get ready for a wild showdown as Kansas battles Iowa State this Saturday!
The Week 13 clash will go down at Jack Trice Stadium in Iowa.
The regular season is winding down, with bowl games on the horizon.
According to SportsBetting3.com Power Rankings, Iowa State has a slight edge.
Kansas is at 5-5 while Iowa State holds a 6-4 record.
We recommend BetRivers or BetMGM for a bet on this game.
Review this game's prop bets and compare the best point spread, total, and moneylines.
Best Jayhawks at Cyclones Odds
| Underdog Kansas | Favorite Iowa State |
|---|---|
| Over | Under |
|---|---|
| Underdog Kansas | Favorite Iowa State |
|---|---|
Matchup Odds FAQs
Iowa State is a -3.5 -105 point spread favorite at BetMGM, while Kansas is a +3.5 -115 point spread underdog at BetMGM.
The best over line is 55.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 55.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
Iowa State is a -170 moneyline favorite at BetMGM and Kansas is a +140 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
Kansas
Iowa State
11/22/25 12:00pm EST | +3.5 -115-3.5 -105 |
Underdog Kansas - Kansas bettors risk $100 to win $86.96 at -115 odds.
A +3.5 Kansas underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.
Favorite Iowa State - Iowa State bettors risk $100 to win $95.24 at -105 odds.
A -3.5 Iowa State favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.
Kansas at Iowa State Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Kansas
Iowa State
No Touchdown
To Score 1st Touchdown
11/22/25 12:00pm EST | +115-165+10000Bet |
Kansas
Iowa State
Game to Overtime
11/22/25 12:00pm EST | Yes +1050No -10000Bet |
Kansas
Iowa State
Both Teams Score 10+
11/22/25 12:00pm EST | Yes -2000No +850Bet |
Kansas
Iowa State
Both Teams Score 20+
11/22/25 12:00pm EST | Yes -190No +145Bet |
| BetMGM | |
Kansas
Iowa State
Both Teams Score 30+
11/22/25 12:00pm EST | Yes +320No -450Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 13 | Kansas vs Iowa State Saturday, November 22nd, 2025 | ISU 38, KU 14 Jack Trice Stadium | Iowa State by 24 |
| 2024 Week 11 | Iowa State vs Kansas Saturday, November 9th, 2024 | KU 45, ISU 36 GEHA Field at Arrowhead Stadium | Kansas by 9 |
| 2023 Week 10 | Kansas vs Iowa State Saturday, November 4th, 2023 | KU 28, ISU 21 Jack Trice Stadium | Kansas by 7 |
| 2022 Week 5 | Iowa State vs Kansas Saturday, October 1st, 2022 | KU 14, ISU 11 David Booth Kansas Memorial Stadium | Kansas by 3 |
| 2021 Week 5 | Kansas vs Iowa State Saturday, October 2nd, 2021 | ISU 59, KU 7 Jack Trice Stadium | Iowa State by 52 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| Iowa State | 5-4 | 0.556 | 8 | 4 | 329 | 242 | 4-2 | 3-2 | W3 |
| Kansas | 3-6 | 0.333 | 5 | 7 | 337 | 321 | 4-3 | 1-4 | L3 |
Kansas & Iowa State Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Kansas Championship OddsNo NCAA College Football Championship TM Kansas YR: futures available
Iowa State Championship OddsNo NCAA College Football Championship TM Iowa State YR: futures available
Kansas & Iowa State Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Fresno State vs Kansas | KU 31, FRES 7 Saturday, August 23rd, 2025 |
| Week 1 | Wagner vs Kansas | KU 46, WAG 7 Friday, August 29th, 2025 |
| Week 2 | Kansas vs Missouri | MIZ 42, KU 31 Saturday, September 6th, 2025 |
| Week 4 | West Virginia vs Kansas | KU 41, WVU 10 Saturday, September 20th, 2025 |
| Week 5 | Cincinnati vs Kansas | CIN 37, KU 34 Saturday, September 27th, 2025 |
| Week 6 | Kansas vs UCF | KU 27, UCF 20 Saturday, October 4th, 2025 |
| Week 7 | Kansas vs Texas Tech | TTU 42, KU 17 Saturday, October 11th, 2025 |
| Week 9 | Kansas State vs Kansas | KSU 42, KU 17 Saturday, October 25th, 2025 |
| Week 10 | Oklahoma State vs Kansas | KU 38, OKST 21 Saturday, November 1st, 2025 |
| Week 11 | Kansas vs Arizona | ARIZ 24, KU 20 Saturday, November 8th, 2025 |
| Week 13 | Kansas vs Iowa State | ISU 38, KU 14 Saturday, November 22nd, 2025 |
| Week 14 | Utah vs Kansas | UTAH 31, KU 21 Friday, November 28th, 2025 |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Iowa State vs Kansas State | ISU 24, KSU 21 Saturday, August 23rd, 2025 |
| Week 1 | South Dakota vs Iowa State | ISU 55, SDAK 7 Saturday, August 30th, 2025 |
| Week 2 | Iowa vs Iowa State | ISU 16, IOWA 13 Saturday, September 6th, 2025 |
| Week 3 | Iowa State vs Arkansas State | ISU 24, ARST 16 Saturday, September 13th, 2025 |
| Week 5 | Arizona vs Iowa State | ISU 39, ARIZ 14 Saturday, September 27th, 2025 |
| Week 6 | Iowa State vs Cincinnati | CIN 38, ISU 30 Saturday, October 4th, 2025 |
| Week 7 | Iowa State vs Colorado | COLO 24, ISU 17 Saturday, October 11th, 2025 |
| Week 9 | BYU vs Iowa State | BYU 41, ISU 27 Saturday, October 25th, 2025 |
| Week 10 | Arizona State vs Iowa State | ASU 24, ISU 19 Saturday, November 1st, 2025 |
| Week 11 | Iowa State vs TCU | ISU 20, TCU 17 Saturday, November 8th, 2025 |
| Week 13 | Kansas vs Iowa State | ISU 38, KU 14 Saturday, November 22nd, 2025 |
| Week 14 | Iowa State vs Oklahoma State | ISU 20, OKST 13 Saturday, November 29th, 2025 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Kansas vs Iowa State College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 22nd, 2025 at 12:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Kansas vs Iowa State Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Kansas vs Iowa State Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other November 22, 2025 NCAAFB Games
- Wagner vs Long Island University
- Minnesota vs Northwestern
- Louisville vs SMU
- Harvard vs Yale
- Western Carolina vs VMI
- Bryant vs Stony Brook
- Miami (FL) vs Virginia Tech
- Delaware vs Wake Forest
- North Carolina Central vs Morgan State
- Missouri vs Oklahoma
- Fordham vs Merrimack College
- Tulsa vs Army
- Rutgers vs Ohio State
- Dartmouth vs Brown
- Albany vs Monmouth
- Lehigh vs Lafayette
- Charlotte vs Georgia
- Baylor vs Arizona
- Washington State vs James Madison
- Old Dominion vs Georgia Southern
- Chattanooga vs Wofford
- Western Illinois vs Gardner-Webb
- Portland State vs Northern Colorado
- Ball State vs Toledo
- Nevada vs Wyoming
- Mercer vs Auburn
- Duquesne vs Robert Morris
- Missouri State vs Kennesaw State
- Eastern Illinois vs Alabama
- Lindenwood vs Southeast Missouri State
- Southern Utah vs North Alabama
- Youngstown State vs Northern Iowa
- Montana State vs Montana
- North Carolina A&T vs Elon
- Tennessee State vs Charleston Southern
- South Dakota State vs North Dakota
- Marshall vs Appalachian State
- Northern Arizona vs Weber State
- Sam Houston State vs Middle Tennessee
- New Mexico State vs UTEP
- Liberty vs Louisiana Tech
- Miss Valley State vs Prairie View A&M
- Incarnate Word vs Houston Christian
- Alabama A&M vs Texas Southern
- UConn vs Florida Atlantic
- South Florida vs UAB
- Michigan State vs Iowa
- Norfolk State vs Howard
- Duke vs North Carolina
- Southern Miss vs South Alabama
- Kentucky vs Vanderbilt
- East Carolina vs UTSA
- Jacksonville State vs FIU
- Syracuse vs Notre Dame
- Arkansas vs Texas
- USC vs Oregon
- Tulane vs Temple
- Michigan vs Maryland
- TCU vs Houston
- Oklahoma State vs UCF
- Kansas State vs Utah
- Georgia State vs Troy
- Coastal Carolina vs South Carolina
- Furman vs Clemson
- Louisiana-Monroe vs Texas State
- New Mexico vs Air Force
- Pittsburgh vs Georgia Tech
- Colorado State vs Boise State
- Nebraska vs Penn State
- Tennessee vs Florida
- North Texas vs Rice
- California vs Stanford
- Illinois vs Wisconsin
- Western Kentucky vs LSU
- BYU vs Cincinnati
- Arizona State vs Colorado
- Washington vs UCLA
- Utah State vs Fresno State
- San Jose State vs San Diego State