The Bulls will play the Mustangs on Saturday, October 2nd, 2021. The matchup takes place at Gerald J. Ford Stadium. Watch this exciting Week 5 matchup at 4:00 pm EDT. Check local listings for coverage on ESPNU.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

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Best Bulls at Mustangs Odds

**Best Point Spread Betting Odds**
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**Best Moneyline Betting Odds**
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South Florida at SMU Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
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	BetMGM Bet
South Florida SMU 10/02/21 4:00pm EDT	Pending BetMGM

Recent Meetings Since 2017

Recent Meetings Since 2017
Week	Game	Result	Margin
2022 Week 11	SMU vs South Florida Saturday, November 12th, 2022	SMU 41, USF 23 Raymond James Stadium	SMU by 18
2021 Week 5	South Florida vs SMU Saturday, October 2nd, 2021	SMU 41, USF 17 Gerald J. Ford Stadium	SMU by 24
2019 Week 5	SMU vs South Florida Saturday, September 28th, 2019	SMU 48, USF 21 Raymond James Stadium	SMU by 27

Team Standings

2021-2022 College Football Regular Season Standings - South Florida, SMU
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
SMU	4-4	0.500	8	4	461	341	5-1	3-3	L2
South Florida	1-7	0.125	2	10	278	416	2-4	0-6	L5

South Florida & SMU Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

South Florida Championship Odds

2025-26 South Florida NCAA College Football Championship Odds
Team
OH,US ncaafb Evnum: 1 Odds Pending

SMU Championship Odds

2025-26 SMU NCAA College Football Championship Odds
Team
OH,US ncaafb Evnum: 1 Odds Pending

South Florida & SMU Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2021-22 South Florida Games & Results
Week	Matchup	Date & Result
Week 1	South Florida vs NC State	NCST 45, USF 0 Thursday, September 2nd, 2021
Week 2	Florida vs South Florida	FLA 42, USF 20 Saturday, September 11th, 2021
Week 3	Florida A&M vs South Florida	USF 38, FAMU 17 Saturday, September 18th, 2021
Week 4	South Florida vs BYU	BYU 35, USF 27 Saturday, September 25th, 2021
Week 5	South Florida vs SMU	SMU 41, USF 17 Saturday, October 2nd, 2021
Week 7	Tulsa vs South Florida	TLSA 32, USF 31 Saturday, October 16th, 2021
Week 8	Temple vs South Florida	USF 34, TEM 14 Saturday, October 23rd, 2021
Week 9	South Florida vs East Carolina	ECU 29, USF 14 Thursday, October 28th, 2021
Week 10	Houston vs South Florida	HOU 54, USF 42 Saturday, November 6th, 2021
Week 11	Cincinnati vs South Florida	CIN 45, USF 28 Friday, November 12th, 2021
Week 12	South Florida vs Tulane	TULN 45, USF 14 Saturday, November 20th, 2021
Week 13	South Florida vs UCF	UCF 17, USF 13 Friday, November 26th, 2021

2021-22 SMU Games & Results
Week	Matchup	Date & Result
Week 1	Abilene Christian vs SMU	SMU 56, ACU 9 Saturday, September 4th, 2021
Week 2	North Texas vs SMU	SMU 35, UNT 12 Saturday, September 11th, 2021
Week 3	SMU vs Louisiana Tech	SMU 39, LT 37 Saturday, September 18th, 2021
Week 4	SMU vs TCU	SMU 42, TCU 34 Saturday, September 25th, 2021
Week 5	South Florida vs SMU	SMU 41, USF 17 Saturday, October 2nd, 2021
Week 6	SMU vs Navy	SMU 31, NAVY 24 Saturday, October 9th, 2021
Week 8	Tulane vs SMU	SMU 55, TULN 26 Thursday, October 21st, 2021
Week 9	SMU vs Houston	HOU 44, SMU 37 Saturday, October 30th, 2021
Week 10	SMU vs Memphis	MEM 28, SMU 25 Saturday, November 6th, 2021
Week 11	UCF vs SMU	SMU 55, UCF 28 Saturday, November 13th, 2021
Week 12	SMU vs Cincinnati	CIN 48, SMU 14 Saturday, November 20th, 2021
Week 13	Tulsa vs SMU	TLSA 34, SMU 31 Saturday, November 27th, 2021
Bowls	SMU vs Virginia Wasabi Fenway Bowl	Wednesday, December 29th, 2021 11:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the South Florida vs SMU College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, October 2nd, 2021 at 4:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the South Florida vs SMU Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the South Florida vs SMU Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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South Florida vs SMU Football Odds

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