Duke vs North Carolina Football Odds

The Blue Devils will play the Tar Heels on Saturday, November 22nd, 2025. The matchup takes place at Kenan Stadium. Watch this exciting Week 13 matchup at 3:30 pm EST.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


Bonus
BetMGM Sportsbook#1 BetMGM
REVIEW
New Customers - Up to $1500 Paid Back in Bonus Bets
Bonus Bets Expire in 7 Days
One new customer offer/Add'l Terms

Bet Now
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Table of Contents

Key Matchup Stats

We're now in the home stretch of the 2025 college football season, with Duke and North Carolina meeting at Kenan Stadium for a key late-season matchup on Saturday, November 22nd, 2025. The playoffs are fast approaching, along with the annual Bowl games that kick off in December. Here's an overview of some important 2025 performance data for each team.

  • SportsBetting3.com Power Rankings - As we wrap up the 2025 regular season, Duke has notched a 94.67 ACC Conference conference power ranking. On the other side of the gridiron, North Carolina has a 93.67 ACC Conference power ranking.
  • Away Duke - Looking at Week 13, Duke heads into this matchup with a 3-2 record as an away team. This ranks them 2nd in the ACC Conference for away team wins in 2025. Remember that a team's overall record and schedule strength will affect whether or not they make a December bowl game or qualify for the playoffs.
  • Home North Carolina - Meanwhile, North Carolina has a 2-3 record as a home team for 2025. They currently rank 5th in the ACC Conference for home team wins. Let's see if they can add another win to their record when they battle Duke on Saturday, November 22nd, 2025.
  • Points Scored - Now late in the 2025 season, Duke ranks 6th (334) in the ACC Conference, with North Carolina currently ranking 15th (187) for points scored in the ACC Conference.
  • Points Against - Duke currently stands 5th (296) in the ACC Conference for points scored by opponents in the 2025 college football season. Their opponent, North Carolina, ranks 11th (220) in the ACC Conference for points against them as the 2025 college football season comes to a close.
  • Team Records - As we head into Week 13, Duke has a 5-5 overall record for the 2025 regular season, with North Carolina possessing a 4-6 standing for the 2025 college football season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for a wild showdown as Duke takes on North Carolina this Saturday!

The Week 13 game will be held at Kenan Stadium, with bowl games approaching soon.

Duke has a higher Power Ranking of 94.67 compared to North Carolina's 93.67.

Duke has a 5-5 standing while North Carolina holds a 4-6 record. We recommend BetRivers or BetMGM for a bet on this game. Review this game's prop bets. Compare the best point spread, total, and moneylines from our partner sportsbooks below.

Best Blue Devils at Tar Heels Odds


Best Point Spread Betting Odds
Underdog

North Carolina
Favorite

Duke
Duke has a -7 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. North Carolina has a +7 -115 point spread at BetMGM OH. North Carolina is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 51.5 points. Risk $105 to win $100. BetMGM has the best under line of 51.5 points. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

North Carolina
Favorite

Duke
Duke is the -250 moneyline favorite. Risk $250 to win $100 on Duke at BetMGM. North Carolina is the +200 underdog at BetMGM. Risk $100 to win $200 on North Carolina. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Duke vs North Carolina College Football game on Saturday, November 22nd, 2025?

Duke is a -7 -105 point spread favorite at BetMGM, while North Carolina is a +7 -115 point spread underdog at BetMGM.

What is the over-under total line for the Duke vs North Carolina College Football game on Saturday, November 22nd, 2025?

The best over line is 51.5 -105 points at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 51.5 -115 points at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the moneyline for the Duke vs North Carolina College Football game on Saturday, November 22nd, 2025?

Duke is a -250 moneyline favorite at BetMGM and North Carolina is a +200 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Duke
North Carolina
11/22/25 3:30pm EST
-7 -105+7 -115
Bet $100 at BetMGM Ohio
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Underdog North Carolina - North Carolina bettors risk $100 to win $86.96 at -115 odds.

A +7 North Carolina underdog bet wins if they lose by 6 or fewer, tie, or win outright. The bet pushes if they lose by 7. Your bet loses if they lose by 8 or more.

Favorite Duke - Duke bettors risk $100 to win $95.24 at -105 odds.

A -7 Duke favorite bet wins if they win by 8 or more. The bet pushes if they win by 7. Your bet loses if they win by 6 or fewer, tie, or lose outright.

Duke at North Carolina Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Duke
North Carolina
No Touchdown
To Score 1st Touchdown
11/22/25 3:30pm EST
-190+130+10000Bet
Duke
North Carolina
Game to Overtime
11/22/25 3:30pm EST
Yes +1150No -10000Bet
Duke
North Carolina
Both Teams Score 10+
11/22/25 3:30pm EST
Yes -1000No +575Bet
Duke
North Carolina
Both Teams Score 20+
11/22/25 3:30pm EST
Yes -120No -105Bet
BetMGM Sports Betting BetMGM
Duke
North Carolina
Both Teams Score 30+
11/22/25 3:30pm EST
Yes +525No -900Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2024
Week 5
North Carolina vs Duke
Saturday, September 28th, 2024
DUKE 21, UNC 20
Wallace Wade Stadium
Duke by 1
2023
Week 11
Duke vs North Carolina
Saturday, November 11th, 2023
UNC 47, DUKE 45 (2OT)
Kenan Stadium
North Carolina by 2
2022
Week 7
North Carolina vs Duke
Saturday, October 15th, 2022
UNC 38, DUKE 35
Wallace Wade Stadium
North Carolina by 3
2021
Week 5
Duke vs North Carolina
Saturday, October 2nd, 2021
UNC 38, DUKE 7
Kenan Stadium
North Carolina by 31

Team Standings

2025-2026 College Football Regular Season Standings - Duke, North Carolina
Team Conf Conf% W L PF PA Home Away Strk
Duke6-20.750754153533-34-2W2
North Carolina2-60.250482312942-42-4L3

Duke & North Carolina Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Duke Championship Odds
2025-26 Duke NCAA College Football Championship Odds

Team
OH,US ncaafb Evnum: 1 Odds Pending
North Carolina Championship Odds

No NCAA College Football Championship TM North Carolina YR: futures available

Duke & North Carolina Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Duke Games & Results
WeekMatchupDate & Result
Week 1Elon vs
Duke
DUKE 45, ELON 17
Thursday, August 28th, 2025
Week 2Illinois vs
Duke
ILL 45, DUKE 19
Saturday, September 6th, 2025
Week 3Duke vs
Tulane
TULN 34, DUKE 27
Saturday, September 13th, 2025
Week 4NC State vs
Duke
DUKE 45, NCSU 33
Saturday, September 20th, 2025
Week 5Duke vs
Syracuse
DUKE 38, SYR 3
Saturday, September 27th, 2025
Week 6Duke vs
California
DUKE 45, CAL 21
Saturday, October 4th, 2025
Week 8Georgia Tech vs
Duke
GT 27, DUKE 18
Saturday, October 18th, 2025
Week 10Duke vs
Clemson
Saturday, November 1st, 2025
12:00 pm EDT
Week 11Duke vs
UConn
Saturday, November 8th, 2025
3:30 pm EST
Week 12Virginia vs
Duke
Saturday, November 15th, 2025
12:00 am EST
Week 13Duke vs
North Carolina
Saturday, November 22nd, 2025
12:00 am EST
Week 14Wake Forest vs
Duke
Saturday, November 29th, 2025
12:00 am EST


2025-26 North Carolina Games & Results
WeekMatchupDate & Result
Week 1TCU vs
North Carolina
TCU 48, UNC 14
Monday, September 1st, 2025
Week 2North Carolina vs
Charlotte
UNC 20, CLT 3
Saturday, September 6th, 2025
Week 3Richmond vs
North Carolina
UNC 41, RICH 6
Saturday, September 13th, 2025
Week 4North Carolina vs
UCF
UCF 34, UNC 9
Saturday, September 20th, 2025
Week 6Clemson vs
North Carolina
CLEM 38, UNC 10
Saturday, October 4th, 2025
Week 8North Carolina vs
California
CAL 21, UNC 18
Friday, October 17th, 2025
Week 9Virginia vs
North Carolina
Saturday, October 25th, 2025
12:00 pm EDT
Week 10North Carolina vs
Syracuse
Friday, October 31st, 2025
7:30 pm EDT
Week 11Stanford vs
North Carolina
Saturday, November 8th, 2025
12:00 am EST
Week 12North Carolina vs
Wake Forest
Saturday, November 15th, 2025
12:00 am EST
Week 13Duke vs
North Carolina
Saturday, November 22nd, 2025
12:00 am EST
Week 14North Carolina vs
NC State
Saturday, November 29th, 2025
12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Duke vs North Carolina College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 22nd, 2025 at 3:30 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Duke vs North Carolina Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Duke vs North Carolina Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other November 22, 2025 NCAAFB Games

Odds Preview 7648