Virginia vs Duke Football Odds

The Cavaliers will play the Blue Devils on Saturday, November 15th, 2025. The matchup takes place at Wallace Wade Stadium. Watch this exciting Week 12 matchup at 3:30 pm EST. Check local listings for coverage on ESPN2.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

It's now the back half of the 2025 college football season, as we begin looking towards the annual bowl games and college football playoffs. Week 12 action features a matchup between Virginia and Duke, kicking off at Wallace Wade Stadium on Saturday, November 15th, 2025. Have a look at the following season performance stats to better handicap this game.

  • SportsBetting3.com Power Rankings - Virginia has a 98.00 conference power ranking for the 2025 season. The conference power ranking for Duke is 95.00.
  • Away Virginia - As Week 12 looms, Virginia currently has a 3-1 record as an away team for the 2025 regular season. This ranks them 1st in the ACC Conference for away team wins. Remember that a team's overall record and schedule strength will affect whether or not they make a bowl game or the playoffs.
  • Home Duke - Duke has a 2-2 record as a home team as they approach Week 12. They currently rank 5th in the ACC Conference for home team wins. Continue monitoring their performance to see if they have a shot at a postseason bowl game or playoff berth.
  • Points Scored - For the 2025 season, Virginia ranks 2nd (337) in the ACC Conference, with Duke currently ranking 6th (317) for points scored in the ACC Conference.
  • Points Against - Virginia stands 8th (216) in the ACC Conference for points scored by opponents in the 2025 college football season. Duke sits at 6th (262) in the ACC Conference for points against them heading into Week 12 of the 2025 season.
  • Team Records - Virginia has a 8-2 overall record for the 2025 regular season, with Duke currently 5-4 for the 2025 college football regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Hold on to your lucky charms, folks! Virginia battles Duke in a Week 12 showdown.

The clash goes down at Wallace Wade Stadium, with the season heating up.

Virginia holds a 98.00 Power Ranking, while Duke sits at 95.00.

The Cavaliers stand tall at 8-2, while the Blue Devils fight at 5-4. Place a bet on this college football game at BetMGM or BetRivers. See this matchup's prop bets below. Compare each sportsbook's point spread, total, and moneyline.

Best Cavaliers at Blue Devils Odds


Best Point Spread Betting Odds
Underdog

Virginia
Favorite

Duke
Duke has a -4.5 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Virginia has a +4.5 -110 point spread at BetMGM OH. Virginia is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 60.5 points. Risk $105 to win $100. BetMGM has the best under line of 60.5 points. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Virginia
Favorite

Duke
Duke is the -190 moneyline favorite. Risk $190 to win $100 on Duke at BetMGM. Virginia is the +155 underdog at BetMGM. Risk $100 to win $155 on Virginia. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Virginia vs Duke College Football game on Saturday, November 15th, 2025?

Duke is a -4.5 -110 point spread favorite at BetMGM, while Virginia is a +4.5 -110 point spread underdog at BetMGM.

What is the over-under total line for the Virginia vs Duke College Football game on Saturday, November 15th, 2025?

The best over line is 60.5 -105 points at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 60.5 -115 points at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the moneyline for the Virginia vs Duke College Football game on Saturday, November 15th, 2025?

Duke is a -190 moneyline favorite at BetMGM and Virginia is a +155 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Virginia
Duke
11/15/25 3:30pm EST
+4.5 -110-4.5 -110
Bet $100 at BetMGM Ohio
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Underdog Virginia - Virginia bettors risk $100 to win $90.91 at -110 odds.

A +4.5 Virginia underdog bet wins if they lose by 4 or fewer, tie, or win outright. Your bet loses if they lose by 5 or more.

Favorite Duke - Duke bettors risk $100 to win $90.91 at -110 odds.

A -4.5 Duke favorite bet wins if they win by 5 or more. Your bet loses if they win by 4 or fewer, tie, or lose outright.

Virginia at Duke Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Virginia
Duke
No Touchdown
To Score 1st Touchdown
11/15/25 3:30pm EST
+125-185+10000Bet
Virginia
Duke
Game to Overtime
11/15/25 3:30pm EST
Yes +1100No -10000Bet
Virginia
Duke
Both Teams Score 10+
11/15/25 3:30pm EST
Yes -5000No +1100Bet
Virginia
Duke
Both Teams Score 20+
11/15/25 3:30pm EST
Yes -275No +210Bet
BetMGM Sports Betting BetMGM
Virginia
Duke
Both Teams Score 30+
11/15/25 3:30pm EST
Yes +220No -295Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 15
Duke vs Virginia
Saturday, December 6th, 2025
DUKE 27, UVA 20 (OT)
Bank of America Stadium
Duke by 7
2025
Week 12
Virginia vs Duke
Saturday, November 15th, 2025
UVA 34, DUKE 17
Wallace Wade Stadium
Virginia by 17
2023
Week 12
Duke vs Virginia
Saturday, November 18th, 2023
UVA 30, DUKE 27
Scott Stadium
Virginia by 3
2022
Week 5
Virginia vs Duke
Saturday, October 1st, 2022
DUKE 38, UVA 17
Wallace Wade Stadium
Duke by 21
2021
Week 7
Duke vs Virginia
Saturday, October 16th, 2021
UVA 48, DUKE 0
Scott Stadium
Virginia by 48

Team Standings

2025-2026 College Football Regular Season Standings - Virginia, Duke
Team Conf Conf% W L PF PA Home Away Strk
#19 Virginia7-10.8751034182676-14-1L1
Duke6-20.750854423733-34-2W3

Virginia & Duke Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Virginia Championship Odds

No NCAA College Football Championship TM Virginia YR: futures available

Duke Championship Odds

No NCAA College Football Championship TM Duke YR: futures available

Virginia & Duke Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Virginia Games & Results
WeekMatchupDate & Result
Week 1Coastal Carolina vs
Virginia
UVA 48, CCU 7
Saturday, August 30th, 2025
Week 2Virginia vs
NC State
NCSU 35, UVA 31
Saturday, September 6th, 2025
Week 3William & Mary vs
Virginia
UVA 55, W&M 16
Saturday, September 13th, 2025
Week 4Stanford vs
Virginia
UVA 48, STAN 20
Saturday, September 20th, 2025
Week 5Florida State vs
Virginia
UVA 46, FSU 38 (2OT)
Friday, September 26th, 2025
Week 6Virginia vs
Louisville
UVA 30, LOU 27 (OT)
Saturday, October 4th, 2025
Week 8Washington State vs
Virginia
UVA 22, WSU 20
Saturday, October 18th, 2025
Week 9Virginia vs
North Carolina
UVA 17, UNC 16 (OT)
Saturday, October 25th, 2025
Week 10Virginia vs
California
UVA 31, CAL 21
Saturday, November 1st, 2025
Week 11Wake Forest vs
Virginia
WAKE 16, UVA 9
Saturday, November 8th, 2025
Week 12Virginia vs
Duke
UVA 34, DUKE 17
Saturday, November 15th, 2025
Week 14Virginia Tech vs
Virginia
UVA 27, VT 7
Saturday, November 29th, 2025
Week 15Duke vs
Virginia
DUKE 27, UVA 20 (OT)
Saturday, December 6th, 2025
BowlsVirginia vs
Missouri
Taxslayer Gator Bowl
Saturday, December 27th, 2025
7:30 pm EST


2025-26 Duke Games & Results
WeekMatchupDate & Result
Week 1Elon vs
Duke
DUKE 45, ELON 17
Thursday, August 28th, 2025
Week 2Illinois vs
Duke
ILL 45, DUKE 19
Saturday, September 6th, 2025
Week 3Duke vs
Tulane
TULN 34, DUKE 27
Saturday, September 13th, 2025
Week 4NC State vs
Duke
DUKE 45, NCSU 33
Saturday, September 20th, 2025
Week 5Duke vs
Syracuse
DUKE 38, SYR 3
Saturday, September 27th, 2025
Week 6Duke vs
California
DUKE 45, CAL 21
Saturday, October 4th, 2025
Week 8Georgia Tech vs
Duke
GT 27, DUKE 18
Saturday, October 18th, 2025
Week 10Duke vs
Clemson
DUKE 46, CLEM 45
Saturday, November 1st, 2025
Week 11Duke vs
UConn
CONN 37, DUKE 34
Saturday, November 8th, 2025
Week 12Virginia vs
Duke
UVA 34, DUKE 17
Saturday, November 15th, 2025
Week 13Duke vs
North Carolina
DUKE 32, UNC 25
Saturday, November 22nd, 2025
Week 14Wake Forest vs
Duke
DUKE 49, WAKE 32
Saturday, November 29th, 2025
Week 15Duke vs
Virginia
DUKE 27, UVA 20 (OT)
Saturday, December 6th, 2025
BowlsArizona State vs
Duke
Tony The Tiger Sun Bowl
Wednesday, December 31st, 2025
2:00 pm EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Virginia vs Duke College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 15th, 2025 at 3:30 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Virginia vs Duke Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Virginia vs Duke Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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