The Broncos will play the Colts on Sunday, September 14th, 2025. The matchup takes place at Lucas Oil Stadium. Watch this exciting Week 2 matchup at 4:05 pm EDT. Check local listings for coverage on CBS.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.

STATE	Bonus

Matchup Stats
Captain Shady Lines
Best Odds
Interactive Odds Example
Prop Bets
Recent Meetings
Team Standings
Futures Odds
Team Pages
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Key Matchup Stats

The 2025-26 NFL regular season keeps rolling for the Denver Broncos and Indianapolis Colts, as they gear up to play an exciting Week 2 matchup at Lucas Oil Stadium. Have a look at the following statistical insights to help you handicap the game.

SportsBetting3.com Power Rankings - The Denver Broncos have started the 2025-26 season with an initial 98.67 power ranking. The Indianapolis Colts currently have a 100.00 power ranking so far.
Away Denver Broncos - Though it's still early in the season, the Denver Broncos have a 0-0-0 record as an away team, ranking them 2nd in the league for away team wins.
Home Indianapolis Colts - Looking at the Indianapolis Colts heading into Week 2, they currently have a 1-0-0 record as a home team. They rank 1st in the league for home team wins.
Points Scored - The Denver Broncos currently rank 11th (20) up to Week 2, with the Indianapolis Colts ranked 4th (33) for points scored in the 2025-26 regular season.
Points Against - The Denver Broncos stand 16th (12) in the early weeks of the regular season for points against. The Indianapolis Colts rank 19th (8) for points against.
Team Records - As Week 2 approaches, the Denver Broncos have a 1-0-0 record, with the Indianapolis Colts at 1-0-0 for the 2025-26 NFL regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Avast ye scallywags! The Denver Broncos be takin' on the Indianapolis Colts in Week 2!

This crucial match be happenin' at Lucas Oil Stadium, where the Broncos must prove their mettle.

According to SportsBetting3.com NFL Power Rankings, the Colts be holdin' a slight advantage over the Broncos.

Denver be standin' at 1-0-0 while the Colts be matchin' that record at 1-0-0.

Bet this game at BetRivers, or BetMGM, review this game's prop bets, and compare the odds below!

Best Broncos at Colts Odds

**Best Point Spread Betting Odds**
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Point Spread odds are updating, please check back soon.

**Best Total Betting Odds**
Over	Under

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**Best Moneyline Betting Odds**
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NFL Odds Example

NFL Odds and Outcomes Explained
Game	Book

Denver Broncos at Indianapolis Colts Prop Bets

NFL Prop Bets
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	Bet
Broncos Colts 9/14/25 4:05pm EDT	Pending

Recent Meetings Since 2021

Recent Meetings Since 2021
Week	Game	Result	Margin
2025 Week 2	Broncos vs Colts Sunday, September 14th, 2025	IND 29, DEN 28 Lucas Oil Stadium	Colts by 1
2024 Week 15	Colts vs Broncos Sunday, December 15th, 2024	DEN 31, IND 13 Empower Field at Mile High	Broncos by 18
2024 Preseason Week 1	Broncos vs Colts Sunday, August 11th, 2024	DEN 34, IND 30 Lucas Oil Stadium	Broncos by 4
2022 Week 5	Colts vs Broncos Thursday, October 6th, 2022	IND 12, DEN 9 (OT) Empower Field at Mile High	Colts by 3

Team Standings

2025-2026 NFL Regular Season Standings - Denver Broncos, Indianapolis Colts
Team	W	L	T	Pct	PF	PA	Home	Away	Div	Div%	Conf	Conf%	Strk	L5
xz* - Denver Broncos	14	3	0	0.824	401	311	8-1-0	6-2-0	5-1-0	0.833	9-3-0	0.750	2W	4-1-0
Indianapolis Colts	8	9	0	0.471	466	412	6-3-0	2-6-0	2-4-0	0.333	6-6-0	0.500	7L	0-5-0

Denver Broncos & Indianapolis Colts Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Denver Broncos Futures Odds

No Super Bowl TM Denver Broncos YR: futures available

Indianapolis Colts Futures Odds

No Super Bowl TM Indianapolis Colts YR: futures available

Denver Broncos & Indianapolis Colts Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Denver Broncos vs Indianapolis Colts NFL Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 14th, 2025 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's NFL page, look for the Denver Broncos vs Indianapolis Colts Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Denver Broncos vs Indianapolis Colts Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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