The Hawkeyes will play the Cyclones on Saturday, September 6th, 2025. The matchup takes place at Jack Trice Stadium. Watch this exciting Week 2 matchup at 12:00 pm EDT. Check local listings for coverage on FOX.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
The 2025 college football season continues with Iowa matching up against Iowa State at Jack Trice Stadium. Let's review how each team is doing so far to better understand how this game will play out.
- SportsBetting3.com Power Rankings - Iowa has a 98.00 conference power ranking for the 2025 season so far. The 2025 conference power ranking for Iowa State is 99.00.
- Away Iowa - Iowa currently has a 0-0 record as an away team for the 2025 regular season, ranking them 1st in the Big Ten Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
- Home Iowa State - So far, Iowa State has a 1-0 record as a home team. They currently rank 2nd in the Big 12 Conference for home team wins in 2025. Keep tabs on this figure, as it will change in the coming weeks.
- Points Scored - Iowa ranks 7th (34) in the Big Ten Conference, with Iowa State currently ranking 1st (79) for points scored in the 2025 Big 12 Conference.
- Points Against - Iowa stands 10th (7) in the Big Ten Conference for points scored by opponents in 2025. Iowa State sits at 3rd (28) in the 2025 Big 12 Conference for points against in the 2025 season.
- Team Records - Iowa has a 1-0 regular season overall record, with Iowa State currently possessing a 2-0 regular season standing for the 2025 NCAAF season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Get ready for a wild showdown at Jack Trice Stadium as Iowa takes on Iowa State.
Iowa State needs this win to stay perfect while Iowa looks to stay undefeated.
Check out SportsBetting3.com to review this game's prop bets and compare the odds below.
Best Hawkeyes at Cyclones Odds
| Underdog Iowa | Favorite Iowa State |
|---|---|
| Over | Under |
|---|---|
| Underdog Iowa | Favorite Iowa State |
|---|---|
Matchup Odds FAQs
Iowa State is a -3.5 -110 point spread favorite at BetMGM, while Iowa is a +3.5 -110 point spread underdog at BetMGM.
The best over line is 42.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 42.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
Iowa State is a -175 moneyline favorite at BetMGM and Iowa is a +145 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
Iowa
Iowa State
9/06/25 12:00pm EDT | +3.5 -110-3.5 -110 |
Underdog Iowa - Iowa bettors risk $100 to win $90.91 at -110 odds.
A +3.5 Iowa underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.
Favorite Iowa State - Iowa State bettors risk $100 to win $90.91 at -110 odds.
A -3.5 Iowa State favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.
Iowa at Iowa State Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Iowa
Iowa State
No Touchdown
To Score 1st Touchdown
9/06/25 12:00pm EDT | +110-160+10000Bet |
Iowa
Iowa State
Game to Overtime
9/06/25 12:00pm EDT | Yes +1050No -10000Bet |
Iowa
Iowa State
Both Teams Score 10+
9/06/25 12:00pm EDT | Yes -450No +310Bet |
Iowa
Iowa State
Both Teams Score 20+
9/06/25 12:00pm EDT | Yes +170No -220Bet |
| BetMGM | |
Iowa
Iowa State
Both Teams Score 30+
9/06/25 12:00pm EDT | Yes +1000No -3000Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 2 | Iowa vs Iowa State Saturday, September 6th, 2025 | ISU 16, IOWA 13 Jack Trice Stadium | Iowa State by 3 |
| 2024 Week 2 | Iowa State vs Iowa Saturday, September 7th, 2024 | ISU 20, IOWA 19 Kinnick Stadium | Iowa State by 1 |
| 2023 Week 2 | Iowa vs Iowa State Saturday, September 9th, 2023 | IOWA 20, ISU 13 Jack Trice Stadium | Iowa by 7 |
| 2022 Week 2 | Iowa State vs Iowa Saturday, September 10th, 2022 | ISU 10, IOWA 7 Kinnick Stadium | Iowa State by 3 |
| 2021 Week 2 | Iowa vs Iowa State Saturday, September 11th, 2021 | IOWA 27, ISU 17 Jack Trice Stadium | Iowa by 10 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| Big 12 | |||||||||
| Iowa State | 2-2 | 0.500 | 5 | 2 | 205 | 133 | 3-0 | 1-2 | L2 |
| Big Ten | |||||||||
| Iowa | 3-1 | 0.750 | 5 | 2 | 209 | 102 | 3-1 | 2-1 | W2 |
Iowa & Iowa State Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Iowa Championship Odds|
Team | BetMGM |
|---|---|
| Iowa | +50000 Bet |
|
Team | BetMGM |
|---|---|
| Iowa State | +15000 Bet |
Iowa & Iowa State Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Albany vs Iowa | IOWA 34, ALB 7 Saturday, August 30th, 2025 |
| Week 2 | Iowa vs Iowa State | ISU 16, IOWA 13 Saturday, September 6th, 2025 |
| Week 3 | UMass vs Iowa | IOWA 47, MASS 7 Saturday, September 13th, 2025 |
| Week 4 | Iowa vs Rutgers | IOWA 38, RUTG 28 Friday, September 19th, 2025 |
| Week 5 | Indiana vs Iowa | IU 20, IOWA 15 Saturday, September 27th, 2025 |
| Week 7 | Iowa vs Wisconsin | IOWA 37, WIS 0 Saturday, October 11th, 2025 |
| Week 8 | Penn State vs Iowa | IOWA 25, PSU 24 Saturday, October 18th, 2025 |
| Week 9 | Minnesota vs Iowa | Saturday, October 25th, 2025 3:30 pm EDT |
| Week 11 | Oregon vs Iowa | Saturday, November 8th, 2025 12:00 am EST |
| Week 12 | Iowa vs USC | Saturday, November 15th, 2025 12:00 am EST |
| Week 13 | Michigan State vs Iowa | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | Iowa vs Nebraska | Friday, November 28th, 2025 12:00 pm EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Iowa State vs Kansas State | ISU 24, KSU 21 Saturday, August 23rd, 2025 |
| Week 1 | South Dakota vs Iowa State | ISU 55, SDAK 7 Saturday, August 30th, 2025 |
| Week 2 | Iowa vs Iowa State | ISU 16, IOWA 13 Saturday, September 6th, 2025 |
| Week 3 | Iowa State vs Arkansas State | ISU 24, ARST 16 Saturday, September 13th, 2025 |
| Week 5 | Arizona vs Iowa State | ISU 39, ARIZ 14 Saturday, September 27th, 2025 |
| Week 6 | Iowa State vs Cincinnati | CIN 38, ISU 30 Saturday, October 4th, 2025 |
| Week 7 | Iowa State vs Colorado | COLO 24, ISU 17 Saturday, October 11th, 2025 |
| Week 9 | BYU vs Iowa State | Saturday, October 25th, 2025 3:30 pm EDT |
| Week 10 | Arizona State vs Iowa State | Saturday, November 1st, 2025 12:00 am EDT |
| Week 11 | Iowa State vs TCU | Saturday, November 8th, 2025 12:00 am EST |
| Week 13 | Kansas vs Iowa State | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | Iowa State vs Oklahoma State | Saturday, November 29th, 2025 12:00 am EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Iowa vs Iowa State College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 6th, 2025 at 12:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Iowa vs Iowa State Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Iowa vs Iowa State Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 6, 2025 NCAAFB Games
- UConn vs Syracuse
- East Texas A&M vs Florida State
- FIU vs Penn State
- Kent State vs Texas Tech
- Liberty vs Jacksonville State
- Central Michigan vs Pittsburgh
- Northwestern State vs Minnesota
- Virginia vs NC State
- Illinois vs Duke
- Baylor vs SMU
- San Jose State vs Texas
- Kennesaw State vs Indiana
- Utah State vs Texas A&M
- Howard vs Temple
- Robert Morris vs Youngstown State
- Presbyterian vs Furman
- Western Carolina vs Wake Forest
- North Dakota State vs Tennessee State
- Idaho State vs New Mexico
- St. Francis (PA) vs Buffalo
- Oklahoma State vs Oregon
- Ole Miss vs Kentucky
- Kansas vs Missouri
- Miami (OH) vs Rutgers
- Austin Peay vs Georgia
- Troy vs Clemson
- Fresno State vs Oregon State
- North Texas vs Western Michigan
- Bowling Green vs Cincinnati
- Texas State vs UTSA
- East Tennessee State vs Tennessee
- Delaware vs Colorado
- UAB vs Navy
- West Virginia vs Ohio
- Middle Tennessee vs Wisconsin
- South Florida vs Florida
- Arkansas State vs Arkansas
- Bryant vs UMass
- Texas Southern vs California
- Missouri State vs Marshall
- Cal Poly vs Utah
- Campbell vs East Carolina
- Colgate vs Villanova
- Davidson vs Elon
- Florida A&M vs Florida Atlantic
- Houston Christian vs Eastern Kentucky
- Maine vs William & Mary
- North Carolina Central vs Old Dominion
- Rhode Island vs Stony Brook
- Richmond vs Wofford
- Holy Cross vs New Hampshire
- Alabama State vs Southern
- Bethune-Cookman vs Miami (FL)
- Alcorn State vs Alabama A&M
- South Dakota vs Lamar
- Arkansas-Pine Bluff vs Central Arkansas
- Southeastern Louisiana vs Murray State
- Portland State vs North Dakota
- North Alabama vs Southeast Missouri State
- Northern Colorado vs Colorado State
- Morehead State vs Illinois State
- Miss Valley State vs Tarleton
- North Carolina vs Charlotte
- Towson vs Morgan State
- West Georgia vs Nicholls
- LIU vs Eastern Michigan
- Western Kentucky vs Toledo
- Tulane vs South Alabama
- Houston vs Rice
- Memphis vs Georgia State
- Army vs Kansas State
- Charleston Southern vs Coastal Carolina
- Southern Illinois vs Purdue
- Ball State vs Auburn
- Boston College vs Michigan State
- Louisiana Tech vs LSU
- Arizona State vs Mississippi State
- Akron vs Nebraska
- Georgia Southern vs USC
- Michigan vs Oklahoma
- Vanderbilt vs Virginia Tech
- Louisiana-Monroe vs Alabama
- Stephen F. Austin vs Abilene Christian
- South Dakota State vs Montana State
- McNeese State vs Louisiana
- UCLA vs UNLV
- North Carolina A&T vs UCF
- South Carolina State vs South Carolina
- UT-Martin vs UTEP
- Southern Utah vs San Diego
- Tulsa vs New Mexico State
- Weber State vs Arizona
- Stanford vs BYU
- San Diego State vs Washington State
- UC Davis vs Washington