Illinois vs Duke Football Odds

The Fighting Illini will play the Blue Devils on Saturday, September 6th, 2025. The matchup takes place at Wallace Wade Stadium. Watch this exciting Week 2 matchup at 12:00 pm EDT. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


Bonus
BetMGM Sportsbook#1 BetMGM
REVIEW
New Customers - Up to $1500 Paid Back in Bonus Bets
Bonus Bets Expire in 7 Days
One new customer offer/Add'l Terms

Bet Now
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Table of Contents

Key Matchup Stats

The 2025 college football season continues with Illinois matching up against Duke at Wallace Wade Stadium. Let's review how each team is doing so far to better understand how this game will play out.

  • SportsBetting3.com Power Rankings - Illinois has a 99.67 conference power ranking for the 2025 season so far. The 2025 conference power ranking for Duke is 98.33.
  • Away Illinois - Illinois currently has a 0-0 record as an away team for the 2025 regular season, ranking them 1st in the Big Ten Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
  • Home Duke - So far, Duke has a 1-0 record as a home team. They currently rank 1st in the ACC Conference for home team wins in 2025. Keep tabs on this figure, as it will change in the coming weeks.
  • Points Scored - Illinois ranks 3rd (52) in the Big Ten Conference, with Duke currently ranking 5th (45) for points scored in the 2025 ACC Conference.
  • Points Against - Illinois stands 12th (3) in the Big Ten Conference for points scored by opponents in 2025. Duke sits at 4th (17) in the 2025 ACC Conference for points against in the 2025 season.
  • Team Records - Illinois has a 1-0 regular season overall record, with Duke currently possessing a 1-0 regular season standing for the 2025 NCAAF season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for an epic showdown at Wallace Wade Stadium as Illinois takes on Duke!

This Week 2 matchup is crucial for Duke as they look to defend their home turf.

With both teams holding a 1-0 record, this game is sure to be a nail-biter.

For the best odds and prop bets, head over to SportsBetting3.com and review this game's prop bets. Don't forget to compare the odds below for a chance to win big!

Best Fighting Illini at Blue Devils Odds


Best Point Spread Betting Odds
Underdog

Duke
Favorite

Illinois
Illinois has a -3 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Duke has a +3 -110 point spread at BetMGM OH. Duke is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 49.5 points. Risk $110 to win $100. BetMGM has the best under line of 49.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Duke
Favorite

Illinois
Illinois is the -155 moneyline favorite. Risk $155 to win $100 on Illinois at BetMGM. Duke is the +130 underdog at BetMGM. Risk $100 to win $130 on Duke. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Illinois vs Duke College Football game on Saturday, September 6th, 2025?

Illinois is a -3 -110 point spread favorite at BetMGM, while Duke is a +3 -110 point spread underdog at BetMGM.

What is the over-under total line for the Illinois vs Duke College Football game on Saturday, September 6th, 2025?

The best over line is 49.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 49.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Illinois vs Duke College Football game on Saturday, September 6th, 2025?

Illinois is a -155 moneyline favorite at BetMGM and Duke is a +130 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Illinois
Duke
9/06/25 12:00pm EDT
-3 -110+3 -110
Bet $100 at BetMGM Ohio
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Underdog Duke - Duke bettors risk $100 to win $90.91 at -110 odds.

A +3 Duke underdog bet wins if they lose by 2 or fewer, tie, or win outright. The bet pushes if they lose by 3. Your bet loses if they lose by 4 or more.

Favorite Illinois - Illinois bettors risk $100 to win $90.91 at -110 odds.

A -3 Illinois favorite bet wins if they win by 4 or more. The bet pushes if they win by 3. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Illinois at Duke Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Illinois
Duke
9/06/25 12:00pm EDT
Pending BetMGM

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin

Team Standings

2025-2026 College Football Regular Season Standings - Illinois, Duke
Team Conf Conf% W L PF PA Home Away Strk
ACC
Duke0-00.0001045171-00-0W1
Big Ten
Illinois0-00.000105231-00-0W1

Illinois & Duke Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Illinois Championship Odds
2025-26 Illinois NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Illinois
Duke Championship Odds
2025-26 Duke NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Duke
+20000
Bet

Illinois & Duke Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Illinois Games & Results
WeekMatchupDate & Result
Week 1Western Illinois vs
Illinois
ILL 52, WIU 3
Friday, August 29th, 2025
Week 2Illinois vs
Duke
Saturday, September 6th, 2025
12:00 pm EDT
Week 3Western Michigan vs
Illinois
Saturday, September 13th, 2025
7:00 pm EDT
Week 4Illinois vs
Indiana
Saturday, September 20th, 2025
12:00 am EDT
Week 5USC vs
Illinois
Saturday, September 27th, 2025
12:00 am EDT
Week 6Illinois vs
Purdue
Saturday, October 4th, 2025
12:00 am EDT
Week 7Ohio State vs
Illinois
Saturday, October 11th, 2025
12:00 am EDT
Week 9Illinois vs
Washington
Saturday, October 25th, 2025
12:00 am EDT
Week 10Rutgers vs
Illinois
Saturday, November 1st, 2025
12:00 am EDT
Week 12Maryland vs
Illinois
Saturday, November 15th, 2025
12:00 am EST
Week 13Illinois vs
Wisconsin
Saturday, November 22nd, 2025
12:00 am EST
Week 14Northwestern vs
Illinois
Saturday, November 29th, 2025
12:00 am EST


2025-26 Duke Games & Results
WeekMatchupDate & Result
Week 1Elon vs
Duke
DUKE 45, ELON 17
Thursday, August 28th, 2025
Week 2Illinois vs
Duke
Saturday, September 6th, 2025
12:00 pm EDT
Week 3Duke vs
Tulane
Saturday, September 13th, 2025
8:00 pm EDT
Week 4NC State vs
Duke
Saturday, September 20th, 2025
12:00 am EDT
Week 5Duke vs
Syracuse
Saturday, September 27th, 2025
12:00 am EDT
Week 6Duke vs
California
Saturday, October 4th, 2025
12:00 am EDT
Week 8Georgia Tech vs
Duke
Saturday, October 18th, 2025
12:00 am EDT
Week 10Duke vs
Clemson
Saturday, November 1st, 2025
12:00 am EDT
Week 11Duke vs
UConn
Saturday, November 8th, 2025
3:30 pm EST
Week 12Virginia vs
Duke
Saturday, November 15th, 2025
12:00 am EST
Week 13Duke vs
North Carolina
Saturday, November 22nd, 2025
12:00 am EST
Week 14Wake Forest vs
Duke
Saturday, November 29th, 2025
12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Illinois vs Duke College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 6th, 2025 at 12:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Illinois vs Duke Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Illinois vs Duke Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other September 6, 2025 NCAAFB Games

Odds Preview 6510