Illinois vs Duke Football Odds

The Fighting Illini will play the Blue Devils on Saturday, September 6th, 2025. The matchup takes place at Wallace Wade Stadium. Watch this exciting Week 2 matchup at 12:00 pm EDT. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

The 2025 college football season continues with Illinois matching up against Duke at Wallace Wade Stadium. Let's review how each team is doing so far to better understand how this game will play out.

  • SportsBetting3.com Power Rankings - Illinois has a 99.67 conference power ranking for the 2025 season so far. The 2025 conference power ranking for Duke is 98.33.
  • Away Illinois - Illinois currently has a 0-0 record as an away team for the 2025 regular season, ranking them 1st in the Big Ten Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
  • Home Duke - So far, Duke has a 1-0 record as a home team. They currently rank 1st in the ACC Conference for home team wins in 2025. Keep tabs on this figure, as it will change in the coming weeks.
  • Points Scored - Illinois ranks 3rd (52) in the Big Ten Conference, with Duke currently ranking 5th (45) for points scored in the 2025 ACC Conference.
  • Points Against - Illinois stands 12th (3) in the Big Ten Conference for points scored by opponents in 2025. Duke sits at 4th (17) in the 2025 ACC Conference for points against in the 2025 season.
  • Team Records - Illinois has a 1-0 regular season overall record, with Duke currently possessing a 1-0 regular season standing for the 2025 NCAAF season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for an epic showdown at Wallace Wade Stadium as Illinois takes on Duke!

This Week 2 matchup is crucial for Duke as they look to defend their home turf.

With both teams holding a 1-0 record, this game is sure to be a nail-biter.

For the best odds and prop bets, head over to SportsBetting3.com and review this game's prop bets. Don't forget to compare the odds below for a chance to win big!

Best Fighting Illini at Blue Devils Odds


Best Point Spread Betting Odds
Underdog

Duke
Favorite

Illinois
Illinois has a -2.5 -114 point spread at BetRivers PA. They are the point spread favorite in this matchup. Duke has a +2.5 -108 point spread at BetRivers PA. Duke is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 49 points. Risk $112 to win $100. BetRivers has the best under line of 49 points. Risk $112 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Duke
Favorite

Illinois
Illinois is the -141 moneyline favorite. Risk $141 to win $100 on Illinois at BetRivers. Duke is the +110 underdog at BetRivers. Risk $100 to win $110 on Duke. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Illinois vs Duke College Football game on Saturday, September 6th, 2025?

Illinois is a -2.5 -114 point spread favorite at BetRivers, while Duke is a +2.5 -108 point spread underdog at BetRivers.

What is the over-under total line for the Illinois vs Duke College Football game on Saturday, September 6th, 2025?

The best over line is 49 -112 points at BetRivers, which means you risk $112 to win $100 betting the over. The best under line is 49 -112 points at BetRivers, and that means you risk $112 to win $100 betting the under.

What is the moneyline for the Illinois vs Duke College Football game on Saturday, September 6th, 2025?

Illinois is a -141 moneyline favorite at BetRivers and Duke is a +110 moneyline underdog at BetRivers.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
Illinois
Duke
9/06/25 12:00pm EDT
-2.5 -114+2.5 -108
Bet $100 at BetRivers Pennsylvania
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Underdog Duke - Duke bettors risk $100 to win $92.59 at -108 odds.

A +2.5 Duke underdog bet wins if they lose by 2 or fewer, tie, or win outright. Your bet loses if they lose by 3 or more.

Favorite Illinois - Illinois bettors risk $100 to win $87.72 at -114 odds.

A -2.5 Illinois favorite bet wins if they win by 3 or more. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Illinois at Duke Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetRivers Sports Betting BetRivers
Bet
Illinois
Duke
First Team To Score
9/06/25 12:00pm EDT
-129-106Bet
Illinois
Duke
Tie
First to 15 Points
9/06/25 12:00pm EDT
-148+102+2800Bet
Illinois
Duke
Tie
First to 20 Points
9/06/25 12:00pm EDT
-129+116+900Bet
Illinois
Duke
Tie
First to 25 Points
9/06/25 12:00pm EDT
+120+175+230Bet
BetRivers Sports Betting BetRivers
Illinois
Duke
Tie
First to 30 Points
9/06/25 12:00pm EDT
+188+270-103Bet
Illinois
Duke
Tie
First to 35 Points
9/06/25 12:00pm EDT
+380+550-315Bet
Duke
Team Total Points
ILL at DUKE
9/06/25 12:00pm EDT
23.5 o -12423.5 u -106Bet
Illinois
Team Total Points
ILL at DUKE
9/06/25 12:00pm EDT
26.5 o -10926.5 u -120Bet
BetRivers Sports Betting BetRivers
Duke
To Score First & Win
ILL at DUKE
9/06/25 12:00pm EDT
Yes +235No -335Bet
Illinois
To Score First & Win
ILL at DUKE
9/06/25 12:00pm EDT
Yes +165No -225Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 2
Illinois vs Duke
Saturday, September 6th, 2025
ILL 45, DUKE 19
Wallace Wade Stadium
Illinois by 26

Team Standings

2025-2026 College Football Regular Season Standings - Illinois, Duke
Team Conf Conf% W L PF PA Home Away Strk
ACC
Duke6-20.750954844123-34-2W4
Big Ten
Illinois5-40.556943823076-12-3W2

Illinois & Duke Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Illinois Championship Odds
2026-27 Illinois NCAA College Football Championship Odds

Team
BetRivers Sports Betting BetRivers
Illinois
+20000
Bet
Duke Championship Odds
2026-27 Duke NCAA College Football Championship Odds

Team
BetRivers Sports Betting BetRivers
Duke
+40000
Bet

Illinois & Duke Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Illinois Games & Results
WeekMatchupDate & Result
Week 1Western Illinois vs
Illinois
ILL 52, WIU 3
Friday, August 29th, 2025
Week 2Illinois vs
Duke
ILL 45, DUKE 19
Saturday, September 6th, 2025
Week 3Western Michigan vs
Illinois
ILL 38, WMU 0
Saturday, September 13th, 2025
Week 4Illinois vs
Indiana
IU 63, ILL 10
Saturday, September 20th, 2025
Week 5USC vs
Illinois
ILL 34, USC 32
Saturday, September 27th, 2025
Week 6Illinois vs
Purdue
ILL 43, PUR 27
Saturday, October 4th, 2025
Week 7Ohio State vs
Illinois
OSU 34, ILL 16
Saturday, October 11th, 2025
Week 9Illinois vs
Washington
WASH 42, ILL 25
Saturday, October 25th, 2025
Week 10Rutgers vs
Illinois
ILL 35, RUTG 13
Saturday, November 1st, 2025
Week 12Maryland vs
Illinois
ILL 24, MD 6
Saturday, November 15th, 2025
Week 13Illinois vs
Wisconsin
WIS 27, ILL 10
Saturday, November 22nd, 2025
Week 14Northwestern vs
Illinois
ILL 20, NU 13
Saturday, November 29th, 2025
BowlsTennessee vs
Illinois
Liberty Mutual Music City Bowl
ILL 30, TENN 28
Tuesday, December 30th, 2025


2025-26 Duke Games & Results
WeekMatchupDate & Result
Week 1Elon vs
Duke
DUKE 45, ELON 17
Thursday, August 28th, 2025
Week 2Illinois vs
Duke
ILL 45, DUKE 19
Saturday, September 6th, 2025
Week 3Duke vs
Tulane
TULN 34, DUKE 27
Saturday, September 13th, 2025
Week 4NC State vs
Duke
DUKE 45, NCSU 33
Saturday, September 20th, 2025
Week 5Duke vs
Syracuse
DUKE 38, SYR 3
Saturday, September 27th, 2025
Week 6Duke vs
California
DUKE 45, CAL 21
Saturday, October 4th, 2025
Week 8Georgia Tech vs
Duke
GT 27, DUKE 18
Saturday, October 18th, 2025
Week 10Duke vs
Clemson
DUKE 46, CLEM 45
Saturday, November 1st, 2025
Week 11Duke vs
UConn
CONN 37, DUKE 34
Saturday, November 8th, 2025
Week 12Virginia vs
Duke
UVA 34, DUKE 17
Saturday, November 15th, 2025
Week 13Duke vs
North Carolina
DUKE 32, UNC 25
Saturday, November 22nd, 2025
Week 14Wake Forest vs
Duke
DUKE 49, WAKE 32
Saturday, November 29th, 2025
Week 15Duke vs
Virginia
DUKE 27, UVA 20 (OT)
Saturday, December 6th, 2025
BowlsArizona State vs
Duke
Tony The Tiger Sun Bowl
DUKE 42, ASU 39
Wednesday, December 31st, 2025

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Illinois vs Duke College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 6th, 2025 at 12:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Illinois vs Duke Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Illinois vs Duke Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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