Southern Illinois vs Purdue Football Odds

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The Salukis will play the Boilermakers on Saturday, September 6th, 2025. The matchup takes place at Ross-Ade Stadium. Watch this exciting Week 2 matchup at 7:30 pm EDT. Check local listings for coverage on BTN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Best Salukis at Boilermakers Odds


Best Point Spread Betting Odds
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Point Spread odds are updating, please check back soon.

Best Total Betting Odds
OverUnder
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Best Moneyline Betting Odds
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Moneyline odds are updating, please check back soon.

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Southern Illinois at Purdue Prop Bets

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Bet
Southern Illinois
Purdue
9/06/25 7:30pm EDT
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Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 2		Southern Illinois vs Purdue
Saturday, September 6th, 2025		PUR 34, SIU 17
Ross-Ade Stadium		Purdue by 17

Team Standings

2025-2026 College Football Regular Season Standings - Southern Illinois, Purdue
Team Conf Conf% W L PF PA Home Away Strk
Missouri Valley
Southern Illinois4-40.500754373203-24-3W1
Big Ten
Purdue0-90.0002102253822-50-5L10

Southern Illinois & Purdue Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Southern Illinois Championship Odds

No NCAA College Football Championship TM Southern Illinois YR: futures available

Purdue Championship Odds

No NCAA College Football Championship TM Purdue YR: futures available

Southern Illinois & Purdue Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Southern Illinois Games & Results
WeekMatchupDate & Result
Week 2Southern Illinois vs
Purdue		PUR 34, SIU 17
Saturday, September 6th, 2025


2025-26 Purdue Games & Results
WeekMatchupDate & Result
Week 1Ball State vs
Purdue		PUR 31, BALL 0
Saturday, August 30th, 2025
Week 2Southern Illinois vs
Purdue		PUR 34, SIU 17
Saturday, September 6th, 2025
Week 3USC vs
Purdue		USC 33, PUR 17
Saturday, September 13th, 2025
Week 4Purdue vs
Notre Dame		ND 56, PUR 30
Saturday, September 20th, 2025
Week 6Illinois vs
Purdue		ILL 43, PUR 27
Saturday, October 4th, 2025
Week 7Purdue vs
Minnesota		MINN 27, PUR 20
Saturday, October 11th, 2025
Week 8Purdue vs
Northwestern		NU 19, PUR 0
Saturday, October 18th, 2025
Week 9Rutgers vs
Purdue		RUTG 27, PUR 24
Saturday, October 25th, 2025
Week 10Purdue vs
Michigan		MICH 21, PUR 16
Saturday, November 1st, 2025
Week 11Ohio State vs
Purdue		OSU 34, PUR 10
Saturday, November 8th, 2025
Week 12Purdue vs
Washington		WASH 49, PUR 13
Saturday, November 15th, 2025
Week 14Indiana vs
Purdue		IU 56, PUR 3
Friday, November 28th, 2025

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Southern Illinois vs Purdue College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 6th, 2025 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Southern Illinois vs Purdue Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Southern Illinois vs Purdue Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other September 6, 2025 NCAAFB Games

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