The Wildcats will play the Cyclones on Saturday, September 27th, 2025. The matchup takes place at Jack Trice Stadium. Watch this exciting Week 5 matchup at 7:00 pm EDT. Check local listings for coverage on ESPN.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
We're now well into the 2025 college football season. Week 5 action features a matchup between Arizona and Iowa State taking place at Jack Trice Stadium. The following are some key season stats to help you size up this game.
- SportsBetting3.com Power Rankings - Arizona has a 98.00 conference power ranking for the 2025 season. The conference power ranking for Iowa State is 97.00.
- Away Arizona - Heading into Week 5, Arizona currently has a 0-0 record as an away team for the 2025 regular season. This ranks them 3rd in the Big 12 Conference for away team wins. Watch this stat carefully as the season progresses.
- Home Iowa State - Iowa State has a 2-0 record as a home team. Looking ahead to this 2025 Week 5 matchup, they rank 2nd in the Big 12 Conference for home team wins. Like the Arizona away record and ranking, you should continually keep tabs on this stat.
- Points Scored - For the 2025 season, Arizona ranks 9th (111) in the Big 12 Conference, with Iowa State currently ranking 8th (119) for points scored in the Big 12 Conference.
- Points Against - Also in 2025, Arizona stands 13th (26) in the Big 12 Conference for points scored by opponents in 2025. Iowa State sits at 9th (57) in the Big 12 Conference for points against in the 2025 season so far.
- Team Records - Arizona has a 3-0 overall record for the 2025 regular season, with Iowa State currently 4-0 for the 2025 NCAAF regular season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Get ready for a wild showdown between Arizona and Iowa State on September 27th!
The game will be held at the electric Jack Trice Stadium, home of the Cyclones.
According to SportsBetting3.com Power Rankings, Arizona has a slight edge over Iowa State.
Arizona is undefeated with a 3-0 record, while Iowa State boasts a perfect 4-0 standing.
Bet this game at BetRivers, or BetMGM and review this game's prop bets. Compare the odds below!
Best Wildcats at Cyclones Odds
| Underdog Arizona | Favorite Iowa State |
|---|---|
| Over | Under |
|---|---|
| Underdog Arizona | Favorite Iowa State |
|---|---|
Matchup Odds FAQs
Iowa State is a -4.5 -105 point spread favorite at BetMGM, while Arizona is a +4.5 -115 point spread underdog at BetMGM.
The best over line is 48.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 48.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
Iowa State is a -190 moneyline favorite at BetMGM and Arizona is a +155 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
Arizona
Iowa State
9/27/25 7:00pm EDT | +4.5 -115-4.5 -105 |
Underdog Arizona - Arizona bettors risk $100 to win $86.96 at -115 odds.
A +4.5 Arizona underdog bet wins if they lose by 4 or fewer, tie, or win outright. Your bet loses if they lose by 5 or more.
Favorite Iowa State - Iowa State bettors risk $100 to win $95.24 at -105 odds.
A -4.5 Iowa State favorite bet wins if they win by 5 or more. Your bet loses if they win by 4 or fewer, tie, or lose outright.
Arizona at Iowa State Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Arizona
Iowa State
No Touchdown
To Score 1st Touchdown
9/27/25 7:00pm EDT | +120-175+10000Bet |
Arizona
Iowa State
Game to Overtime
9/27/25 7:00pm EDT | Yes +1050No -10000Bet |
Arizona
Iowa State
Both Teams Score 10+
9/27/25 7:00pm EDT | Yes -900No +525Bet |
Arizona
Iowa State
Both Teams Score 20+
9/27/25 7:00pm EDT | Yes -102No -125Bet |
| BetMGM | |
Arizona
Iowa State
Both Teams Score 30+
9/27/25 7:00pm EDT | Yes +575No -1000Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 5 | Arizona vs Iowa State Saturday, September 27th, 2025 | ISU 39, ARIZ 14 Jack Trice Stadium | Iowa State by 25 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| #25 Arizona | 5-3 | 0.625 | 8 | 3 | 368 | 220 | 6-1 | 2-2 | W4 |
| Iowa State | 4-4 | 0.500 | 7 | 4 | 309 | 229 | 4-2 | 2-2 | W2 |
Arizona & Iowa State Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Arizona Championship OddsNo NCAA College Football Championship TM Arizona YR: futures available
Iowa State Championship OddsNo NCAA College Football Championship TM Iowa State YR: futures available
Arizona & Iowa State Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Hawaii vs Arizona | ARIZ 40, HAW 6 Saturday, August 30th, 2025 |
| Week 2 | Weber State vs Arizona | ARIZ 48, WEB 3 Saturday, September 6th, 2025 |
| Week 3 | Kansas State vs Arizona | ARIZ 23, KSU 17 Friday, September 12th, 2025 |
| Week 5 | Arizona vs Iowa State | ISU 39, ARIZ 14 Saturday, September 27th, 2025 |
| Week 6 | Oklahoma State vs Arizona | ARIZ 41, OKST 13 Saturday, October 4th, 2025 |
| Week 7 | BYU vs Arizona | BYU 33, ARIZ 27 (2OT) Saturday, October 11th, 2025 |
| Week 8 | Arizona vs Houston | HOU 31, ARIZ 28 Saturday, October 18th, 2025 |
| Week 10 | Arizona vs Colorado | Saturday, November 1st, 2025 12:00 am EDT |
| Week 11 | Kansas vs Arizona | Saturday, November 8th, 2025 12:00 am EST |
| Week 12 | Arizona vs Cincinnati | Saturday, November 15th, 2025 12:00 am EST |
| Week 13 | Baylor vs Arizona | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | Arizona vs Arizona State | Friday, November 28th, 2025 12:00 am EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Iowa State vs Kansas State | ISU 24, KSU 21 Saturday, August 23rd, 2025 |
| Week 1 | South Dakota vs Iowa State | ISU 55, SDAK 7 Saturday, August 30th, 2025 |
| Week 2 | Iowa vs Iowa State | ISU 16, IOWA 13 Saturday, September 6th, 2025 |
| Week 3 | Iowa State vs Arkansas State | ISU 24, ARST 16 Saturday, September 13th, 2025 |
| Week 5 | Arizona vs Iowa State | ISU 39, ARIZ 14 Saturday, September 27th, 2025 |
| Week 6 | Iowa State vs Cincinnati | CIN 38, ISU 30 Saturday, October 4th, 2025 |
| Week 7 | Iowa State vs Colorado | COLO 24, ISU 17 Saturday, October 11th, 2025 |
| Week 9 | BYU vs Iowa State | Saturday, October 25th, 2025 3:30 pm EDT |
| Week 10 | Arizona State vs Iowa State | Saturday, November 1st, 2025 12:00 am EDT |
| Week 11 | Iowa State vs TCU | Saturday, November 8th, 2025 12:00 am EST |
| Week 13 | Kansas vs Iowa State | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | Iowa State vs Oklahoma State | Saturday, November 29th, 2025 12:00 am EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Arizona vs Iowa State College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 27th, 2025 at 7:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Arizona vs Iowa State Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Arizona vs Iowa State Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 27, 2025 NCAAFB Games
- South Alabama vs North Texas
- Louisville vs Pittsburgh
- Duke vs Syracuse
- Georgia Tech vs Wake Forest
- New Haven vs Duquesne
- Norfolk State vs Wagner
- Bowling Green vs Ohio
- Stetson vs Dayton
- Penn vs Lehigh
- Rutgers vs Minnesota
- UCF vs Kansas State
- Cincinnati vs Kansas
- Georgetown vs Columbia
- Delaware State vs Sacred Heart
- Dartmouth vs Central Connecticut
- Notre Dame vs Arkansas
- Cornell vs Yale
- USC vs Illinois
- Utah State vs Vanderbilt
- Eastern Michigan vs Central Michigan
- Georgia Southern vs James Madison
- Howard vs Richmond
- South Dakota vs North Dakota State
- Utah Tech vs Austin Peay
- Hampton vs Elon
- Arkansas State vs Louisiana-Monroe
- Alabama State vs Florida A&M
- Idaho State vs Northern Colorado
- Mercyhurst vs South Dakota State
- Alabama A&M vs Bethune-Cookman
- Lindenwood vs Miami (OH)
- Merrimack College vs Stony Brook
- Furman vs Samford
- North Carolina A&T vs Maine
- Princeton vs Lafayette
- Western Carolina vs Campbell
- San Diego State vs Northern Illinois
- UConn vs Buffalo
- UCLA vs Northwestern
- Akron vs Toledo
- Baylor vs Oklahoma State
- California vs Boston College
- LSU vs Ole Miss
- Rice vs Navy
- Utah vs West Virginia
- Ohio State vs Washington
- Indiana vs Iowa
- Auburn vs Texas A&M
- New Mexico State vs New Mexico
- Hawaii vs Air Force
- Tulane vs Tulsa
- Tennessee vs Mississippi State
- Mercer vs East Tennessee State
- The Citadel vs Chattanooga
- Nicholls vs Eastern Kentucky
- South Carolina State vs Charleston Southern
- St. Francis (PA) vs Bucknell
- Brown vs Harvard
- Middle Tennessee vs Kennesaw State
- Liberty vs Old Dominion
- Rhode Island vs Western Michigan
- Virginia Tech vs NC State
- UTRGV vs Southeastern Louisiana
- Alcorn State vs Arkansas-Pine Bluff
- Memphis vs Florida Atlantic
- Southeast Missouri State vs UT-Martin
- Abilene Christian vs Incarnate Word
- Central Arkansas vs Lamar
- Grambling State vs Prairie View A&M
- Jacksonville State vs Southern Miss
- North Carolina Central vs East Texas A&M
- Jackson State vs Southern
- Western Kentucky vs Missouri State
- San Jose State vs Stanford
- UMass vs Missouri
- Alabama vs Georgia
- Oregon vs Penn State
- Appalachian State vs Boise State
- Washington State vs Colorado State
- Kentucky vs South Carolina
- McNeese State vs Stephen F. Austin
- Marshall vs Louisiana
- West Georgia vs Southern Utah
- Louisiana Tech vs UTEP
- Cal Poly vs Sacramento State
- Weber State vs UC Davis
- Idaho vs Montana
- BYU vs Colorado