The Trojans will play the Fighting Illini on Saturday, September 27th, 2025. The matchup takes place at Memorial Stadium (Champaign, IL). Watch this exciting Week 5 matchup at 12:00 pm EDT. Check local listings for coverage on FOX.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
| Bonus | |
|---|---|
 #1 BetMGMREVIEW | New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966 |
Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
We're now well into the 2025 college football season. Week 5 action features a matchup between USC and Illinois taking place at Memorial Stadium (Champaign, IL). The following are some key season stats to help you size up this game.
- SportsBetting3.com Power Rankings - USC has a 99.33 conference power ranking for the 2025 season. The conference power ranking for Illinois is 94.33.
- Away USC - Heading into Week 5, USC currently has a 1-0 record as an away team for the 2025 regular season. This ranks them 1st in the Big Ten Conference for away team wins. Watch this stat carefully as the season progresses.
- Home Illinois - Illinois has a 2-0 record as a home team. Looking ahead to this 2025 Week 5 matchup, they rank 3rd in the Big Ten Conference for home team wins. Like the USC away record and ranking, you should continually keep tabs on this stat.
- Points Scored - For the 2025 season, USC ranks 2nd (210) in the Big Ten Conference, with Illinois currently ranking 6th (145) for points scored in the Big Ten Conference.
- Points Against - Also in 2025, USC stands 6th (81) in the Big Ten Conference for points scored by opponents in 2025. Illinois sits at 5th (85) in the Big Ten Conference for points against in the 2025 season so far.
- Team Records - USC has a 4-0 overall record for the 2025 regular season, with Illinois currently 3-1 for the 2025 NCAAF regular season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Get ready for a wild showdown as USC faces off against Illinois in a key Week 5 matchup!
This intense game will be held at Memorial Stadium in Champaign, IL, adding to the excitement.
According to SportsBetting3.com Power Rankings, USC leads with a rating of 99.33 over Illinois at 94.33.
USC is currently undefeated with a 4-0 standing, while Illinois holds a 3-1 record. Bet this game at BetRivers, or BetMGM, review this game's prop bets, and compare the odds below for an unforgettable experience!
Best Trojans at Fighting Illini Odds
| Underdog Illinois | Favorite USC |
|---|---|
| Over | Under |
|---|---|
| Underdog Illinois | Favorite USC |
|---|---|
Matchup Odds FAQs
USC is a -6.5 -115 point spread favorite at BetMGM, while Illinois is a +6.5 -105 point spread underdog at BetMGM.
The best over line is 61.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 61.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.
USC is a -250 moneyline favorite at BetMGM and Illinois is a +200 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
USC
Illinois
9/27/25 12:00pm EDT | -6.5 -115+6.5 -105 |
Underdog Illinois - Illinois bettors risk $100 to win $95.24 at -105 odds.
A +6.5 Illinois underdog bet wins if they lose by 6 or fewer, tie, or win outright. Your bet loses if they lose by 7 or more.
Favorite USC - USC bettors risk $100 to win $86.96 at -115 odds.
A -6.5 USC favorite bet wins if they win by 7 or more. Your bet loses if they win by 6 or fewer, tie, or lose outright.
USC at Illinois Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
USC
Illinois
No Touchdown
To Score 1st Touchdown
9/27/25 12:00pm EDT | -190+130+10000Bet |
USC
Illinois
Game to Overtime
9/27/25 12:00pm EDT | Yes +1050No -10000Bet |
USC
Illinois
Both Teams Score 10+
9/27/25 12:00pm EDT | Yes -3000No +1050Bet |
USC
Illinois
Both Teams Score 20+
9/27/25 12:00pm EDT | Yes -295No +220Bet |
| BetMGM | |
USC
Illinois
Both Teams Score 30+
9/27/25 12:00pm EDT | Yes +190No -250Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 5 | USC vs Illinois Saturday, September 27th, 2025 | ILL 34, USC 32 Memorial Stadium (Champaign, IL) | Illinois by 2 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| #17 Illinois | 2-1 | 0.667 | 5 | 1 | 222 | 144 | 3-0 | 2-1 | W2 |
| USC | 2-1 | 0.667 | 4 | 1 | 242 | 115 | 3-0 | 1-1 | L1 |
USC & Illinois Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
USC Championship Odds|
Team | BetMGM |
|---|---|
| USC | +8000 Bet |
|
Team | BetMGM |
|---|---|
| Illinois |
USC & Illinois Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Missouri State vs USC | USC 73, MOST 13 Saturday, August 30th, 2025 |
| Week 2 | Georgia Southern vs USC | USC 59, GASO 20 Saturday, September 6th, 2025 |
| Week 3 | USC vs Purdue | USC 33, PUR 17 Saturday, September 13th, 2025 |
| Week 4 | Michigan State vs USC | USC 45, MSU 31 Saturday, September 20th, 2025 |
| Week 5 | USC vs Illinois | ILL 34, USC 32 Saturday, September 27th, 2025 |
| Week 7 | Michigan vs USC | Saturday, October 11th, 2025 7:30 pm EDT |
| Week 8 | USC vs Notre Dame | Saturday, October 18th, 2025 7:30 pm EDT |
| Week 10 | USC vs Nebraska | Saturday, November 1st, 2025 12:00 am EDT |
| Week 11 | Northwestern vs USC | Friday, November 7th, 2025 9:00 pm EST |
| Week 12 | Iowa vs USC | Saturday, November 15th, 2025 12:00 am EST |
| Week 13 | USC vs Oregon | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | UCLA vs USC | Saturday, November 29th, 2025 12:00 am EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Western Illinois vs Illinois | ILL 52, WIU 3 Friday, August 29th, 2025 |
| Week 2 | Illinois vs Duke | ILL 45, DUKE 19 Saturday, September 6th, 2025 |
| Week 3 | Western Michigan vs Illinois | ILL 38, WMU 0 Saturday, September 13th, 2025 |
| Week 4 | Illinois vs Indiana | IU 63, ILL 10 Saturday, September 20th, 2025 |
| Week 5 | USC vs Illinois | ILL 34, USC 32 Saturday, September 27th, 2025 |
| Week 6 | Illinois vs Purdue | ILL 43, PUR 27 Saturday, October 4th, 2025 |
| Week 7 | Ohio State vs Illinois | Saturday, October 11th, 2025 12:00 pm EDT |
| Week 9 | Illinois vs Washington | Saturday, October 25th, 2025 12:00 am EDT |
| Week 10 | Rutgers vs Illinois | Saturday, November 1st, 2025 12:00 am EDT |
| Week 12 | Maryland vs Illinois | Saturday, November 15th, 2025 12:00 am EST |
| Week 13 | Illinois vs Wisconsin | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | Northwestern vs Illinois | Saturday, November 29th, 2025 12:00 am EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the USC vs Illinois College Football Game
-
Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 27th, 2025 at 12:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
-
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
-
Tap to the sportsbook's College Football page, look for the USC vs Illinois Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the USC vs Illinois Game.
-
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 27, 2025 NCAAFB Games
- South Alabama vs North Texas - 9/27/25 12:00pm EDT
- Louisville vs Pittsburgh - 9/27/25 12:00pm EDT
- Duke vs Syracuse - 9/27/25 12:00pm EDT
- Georgia Tech vs Wake Forest - 9/27/25 12:00pm EDT
- New Haven vs Duquesne - 9/27/25 12:00pm EDT
- Norfolk State vs Wagner - 9/27/25 12:00pm EDT
- Bowling Green vs Ohio - 9/27/25 12:00pm EDT
- Stetson vs Dayton - 9/27/25 12:00pm EDT
- Penn vs Lehigh - 9/27/25 12:00pm EDT
- Rutgers vs Minnesota - 9/27/25 12:00pm EDT
- UCF vs Kansas State - 9/27/25 12:00pm EDT
- Cincinnati vs Kansas - 9/27/25 12:00pm EDT
- Georgetown vs Columbia - 9/27/25 12:00pm EDT
- Delaware State vs Sacred Heart - 9/27/25 12:00pm EDT
- Dartmouth vs Central Connecticut - 9/27/25 12:00pm EDT
- Notre Dame vs Arkansas - 9/27/25 12:00pm EDT
- Cornell vs Yale - 9/27/25 12:00pm EDT
- Utah State vs Vanderbilt - 9/27/25 12:45pm EDT
- Eastern Michigan vs Central Michigan - 9/27/25 1:00pm EDT
- Georgia Southern vs James Madison - 9/27/25 1:30pm EDT
- Howard vs Richmond - 9/27/25 2:00pm EDT
- South Dakota vs North Dakota State - 9/27/25 2:00pm EDT
- Utah Tech vs Austin Peay - 9/27/25 2:00pm EDT
- Hampton vs Elon - 9/27/25 2:00pm EDT
- Arkansas State vs Louisiana-Monroe - 9/27/25 3:00pm EDT
- Alabama State vs Florida A&M - 9/27/25 3:00pm EDT
- Idaho State vs Northern Colorado - 9/27/25 3:00pm EDT
- Mercyhurst vs South Dakota State - 9/27/25 3:00pm EDT
- Alabama A&M vs Bethune-Cookman - 9/27/25 3:00pm EDT
- Lindenwood vs Miami (OH) - 9/27/25 3:30pm EDT
- Merrimack College vs Stony Brook - 9/27/25 3:30pm EDT
- Furman vs Samford - 9/27/25 3:30pm EDT
- North Carolina A&T vs Maine - 9/27/25 3:30pm EDT
- Princeton vs Lafayette - 9/27/25 3:30pm EDT
- Western Carolina vs Campbell - 9/27/25 3:30pm EDT
- San Diego State vs Northern Illinois - 9/27/25 3:30pm EDT
- UConn vs Buffalo - 9/27/25 3:30pm EDT
- UCLA vs Northwestern - 9/27/25 3:30pm EDT
- Akron vs Toledo - 9/27/25 3:30pm EDT
- Baylor vs Oklahoma State - 9/27/25 3:30pm EDT
- California vs Boston College - 9/27/25 3:30pm EDT
- LSU vs Ole Miss - 9/27/25 3:30pm EDT
- Rice vs Navy - 9/27/25 3:30pm EDT
- Utah vs West Virginia - 9/27/25 3:30pm EDT
- Ohio State vs Washington - 9/27/25 3:30pm EDT
- Indiana vs Iowa - 9/27/25 3:30pm EDT
- Auburn vs Texas A&M - 9/27/25 3:30pm EDT
- New Mexico State vs New Mexico - 9/27/25 4:00pm EDT
- Hawaii vs Air Force - 9/27/25 4:00pm EDT
- Tulane vs Tulsa - 9/27/25 4:00pm EDT
- Tennessee vs Mississippi State - 9/27/25 4:15pm EDT
- Mercer vs East Tennessee State - 9/27/25 5:30pm EDT
- The Citadel vs Chattanooga - 9/27/25 6:00pm EDT
- Nicholls vs Eastern Kentucky - 9/27/25 6:00pm EDT
- South Carolina State vs Charleston Southern - 9/27/25 6:00pm EDT
- St. Francis (PA) vs Bucknell - 9/27/25 6:00pm EDT
- Brown vs Harvard - 9/27/25 6:00pm EDT
- Middle Tennessee vs Kennesaw State - 9/27/25 6:00pm EDT
- Liberty vs Old Dominion - 9/27/25 6:00pm EDT
- Rhode Island vs Western Michigan - 9/27/25 6:30pm EDT
- Virginia Tech vs NC State - 9/27/25 7:00pm EDT
- UTRGV vs Southeastern Louisiana - 9/27/25 7:00pm EDT
- Alcorn State vs Arkansas-Pine Bluff - 9/27/25 7:00pm EDT
- Memphis vs Florida Atlantic - 9/27/25 7:00pm EDT
- Southeast Missouri State vs UT-Martin - 9/27/25 7:00pm EDT
- Abilene Christian vs Incarnate Word - 9/27/25 7:00pm EDT
- Central Arkansas vs Lamar - 9/27/25 7:00pm EDT
- Grambling State vs Prairie View A&M - 9/27/25 7:00pm EDT
- Jacksonville State vs Southern Miss - 9/27/25 7:00pm EDT
- North Carolina Central vs East Texas A&M - 9/27/25 7:00pm EDT
- Jackson State vs Southern - 9/27/25 7:00pm EDT
- Arizona vs Iowa State - 9/27/25 7:00pm EDT
- Western Kentucky vs Missouri State - 9/27/25 7:00pm EDT
- San Jose State vs Stanford - 9/27/25 7:30pm EDT
- UMass vs Missouri - 9/27/25 7:30pm EDT
- Alabama vs Georgia - 9/27/25 7:30pm EDT
- Oregon vs Penn State - 9/27/25 7:30pm EDT
- Appalachian State vs Boise State - 9/27/25 7:30pm EDT
- Washington State vs Colorado State - 9/27/25 7:30pm EDT
- Kentucky vs South Carolina - 9/27/25 7:45pm EDT
- McNeese State vs Stephen F. Austin - 9/27/25 8:00pm EDT
- Marshall vs Louisiana - 9/27/25 8:00pm EDT
- West Georgia vs Southern Utah - 9/27/25 8:30pm EDT
- Louisiana Tech vs UTEP - 9/27/25 9:00pm EDT
- Cal Poly vs Sacramento State - 9/27/25 9:00pm EDT
- Weber State vs UC Davis - 9/27/25 10:00pm EDT
- Idaho vs Montana - 9/27/25 10:00pm EDT
- BYU vs Colorado - 9/27/25 10:15pm EDT