Nicholls vs Eastern Kentucky Football Odds

The Colonels will play the Colonels on Saturday, September 27th, 2025.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

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Best Colonels at Colonels Odds

**Best Point Spread Betting Odds**
Underdog Nicholls	Favorite Eastern Kentucky
+2.5 -112 BetRivers Bet	-2.5 -114 BetRivers Bet

Eastern Kentucky has a -2.5 -114 point spread at BetRivers PA. They are the point spread favorite in this matchup. Nicholls has a +2.5 -112 point spread at BetRivers PA. Nicholls is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

**Best Total Betting Odds**
Over	Under
42.5 o -112 BetRivers Bet	42.5 u -114 BetRivers Bet

BetRivers has the best over line of 42.5 points. Risk $112 to win $100. BetRivers has the best under line of 42.5 points. Risk $114 to win $100. Our tutorial explains more about total bets.

**Best Moneyline Betting Odds**
Underdog Nicholls	Favorite Eastern Kentucky
+110 BetRivers Bet	-141 BetRivers Bet

Eastern Kentucky is the -141 moneyline favorite. Risk $141 to win $100 on Eastern Kentucky at BetRivers. Nicholls is the +110 underdog at BetRivers. Risk $100 to win $110 on Nicholls. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Nicholls vs Eastern Kentucky College Football game on Saturday, September 27th, 2025?

Eastern Kentucky is a -2.5 -114 point spread favorite at BetRivers, while Nicholls is a +2.5 -112 point spread underdog at BetRivers.

What is the over-under total line for the Nicholls vs Eastern Kentucky College Football game on Saturday, September 27th, 2025?

The best over line is 42.5 -112 points at BetRivers, which means you risk $112 to win $100 betting the over. The best under line is 42.5 -114 points at BetRivers, and that means you risk $114 to win $100 betting the under.

What is the moneyline for the Nicholls vs Eastern Kentucky College Football game on Saturday, September 27th, 2025?

Eastern Kentucky is a -141 moneyline favorite at BetRivers and Nicholls is a +110 moneyline underdog at BetRivers.

College Football Odds Example

College Football Odds and Outcomes Explained
Game	BetRivers Bet
Nicholls Eastern Kentucky 9/27/25 6:00pm EDT	+2.5 -112 -2.5 -114

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Underdog Nicholls - Nicholls bettors risk $100 to win $89.29 at -112 odds.

A +2.5 Nicholls underdog bet wins if they lose by 2 or fewer, tie, or win outright. Your bet loses if they lose by 3 or more.

Favorite Eastern Kentucky - Eastern Kentucky bettors risk $100 to win $87.72 at -114 odds.

A -2.5 Eastern Kentucky favorite bet wins if they win by 3 or more. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Nicholls at Eastern Kentucky Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
	BetRivers Bet
Nicholls Eastern Kentucky 9/27/25 6:00pm EDT	Pending BetRivers

Recent Meetings Since 2021

Recent Meetings Since 2021
Week	Game	Result	Margin

Team Standings

2025-2026 College Football Regular Season Standings - Nicholls, Eastern Kentucky
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
Southland
Nicholls	4-4	0.500	4	8	219	299	4-1	0-7	L1
UAC
Eastern Kentucky	3-5	0.375	5	7	232	292	3-3	2-4	W1

Nicholls & Eastern Kentucky Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Nicholls Championship Odds

No NCAA College Football Championship TM Nicholls YR: futures available

Eastern Kentucky Championship Odds

No NCAA College Football Championship TM Eastern Kentucky YR: futures available

Nicholls & Eastern Kentucky Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2025-26 Nicholls Games & Results
Week	Matchup	Date & Result
Week 1	Nicholls vs Troy	TROY 38, NICH 20 Saturday, August 30th, 2025
Week 4	Nicholls vs Texas State	TXST 35, NICH 3 Saturday, September 20th, 2025

2025-26 Eastern Kentucky Games & Results
Week	Matchup	Date & Result
Week 1	Eastern Kentucky vs Louisville	LOU 51, EKU 17 Saturday, August 30th, 2025
Week 3	Eastern Kentucky vs Marshall	MRSH 38, EKU 7 Saturday, September 13th, 2025

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Nicholls vs Eastern Kentucky College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 27th, 2025 at 6:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the Nicholls vs Eastern Kentucky Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Nicholls vs Eastern Kentucky Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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