USC vs Nebraska Football Odds

The Trojans will play the Cornhuskers on Saturday, November 1st, 2025. The matchup takes place at Memorial Stadium (Lincoln, NE). Watch this exciting Week 10 matchup at 7:30 pm EDT. Check local listings for coverage on NBC.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

It's now the back half of the 2025 college football season, as we begin looking towards the annual bowl games and college football playoffs. Week 10 action features a matchup between USC and Nebraska, kicking off at Memorial Stadium (Lincoln, NE) on Saturday, November 1st, 2025. Have a look at the following season performance stats to better handicap this game.

  • SportsBetting3.com Power Rankings - USC has a 95.67 conference power ranking for the 2025 season. The conference power ranking for Nebraska is 96.00.
  • Away USC - As Week 10 looms, USC currently has a 1-2 record as an away team for the 2025 regular season. This ranks them 3rd in the Big Ten Conference for away team wins. Remember that a team's overall record and schedule strength will affect whether or not they make a bowl game or the playoffs.
  • Home Nebraska - Nebraska has a 4-1 record as a home team as they approach Week 10. They currently rank 3rd in the Big Ten Conference for home team wins. Continue monitoring their performance to see if they have a shot at a postseason bowl game or playoff berth.
  • Points Scored - For the 2025 season, USC ranks 3rd (297) in the Big Ten Conference, with Nebraska currently ranking 5th (280) for points scored in the Big Ten Conference.
  • Points Against - USC stands 9th (162) in the Big Ten Conference for points scored by opponents in the 2025 college football season. Nebraska sits at 10th (157) in the Big Ten Conference for points against them heading into Week 10 of the 2025 season.
  • Team Records - USC has a 5-2 overall record for the 2025 regular season, with Nebraska currently 6-2 for the 2025 college football regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Top o' the morning to ya, lads and lasses! USC is ready to rumble!

Get ready for a showdown at Memorial Stadium in Lincoln, NE this Saturday.

In the SportsBetting3.com Power Rankings, USC is just a hair behind Nebraska.

USC is 5-2, while Nebraska is slightly ahead at 6-2. Place a bet now!

See this matchup's prop bets below and compare each sportsbook's point spread.

Best Trojans at Cornhuskers Odds


Best Point Spread Betting Odds
Underdog

Nebraska
Favorite

USC
USC has a -6.5 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Nebraska has a +6.5 -110 point spread at BetMGM OH. Nebraska is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 59.5 points. Risk $105 to win $100. BetMGM has the best under line of 59.5 points. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Nebraska
Favorite

USC
USC is the -250 moneyline favorite. Risk $250 to win $100 on USC at BetMGM. Nebraska is the +200 underdog at BetMGM. Risk $100 to win $200 on Nebraska. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the USC vs Nebraska College Football game on Saturday, November 1st, 2025?

USC is a -6.5 -110 point spread favorite at BetMGM, while Nebraska is a +6.5 -110 point spread underdog at BetMGM.

What is the over-under total line for the USC vs Nebraska College Football game on Saturday, November 1st, 2025?

The best over line is 59.5 -105 points at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 59.5 -115 points at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the moneyline for the USC vs Nebraska College Football game on Saturday, November 1st, 2025?

USC is a -250 moneyline favorite at BetMGM and Nebraska is a +200 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
USC
Nebraska
11/01/25 7:30pm EDT
-6.5 -110+6.5 -110
Bet $100 at BetMGM Ohio
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Underdog Nebraska - Nebraska bettors risk $100 to win $90.91 at -110 odds.

A +6.5 Nebraska underdog bet wins if they lose by 6 or fewer, tie, or win outright. Your bet loses if they lose by 7 or more.

Favorite USC - USC bettors risk $100 to win $90.91 at -110 odds.

A -6.5 USC favorite bet wins if they win by 7 or more. Your bet loses if they win by 6 or fewer, tie, or lose outright.

USC at Nebraska Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
USC
Nebraska
11/01/25 7:30pm EDT
Pending BetMGM

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2024
Week 12
Nebraska vs USC
Saturday, November 16th, 2024
USC 28, NEB 20
Los Angeles Memorial Coliseum
USC by 8

Team Standings

2025-2026 College Football Regular Season Standings - USC, Nebraska
Team Conf Conf% W L PF PA Home Away Strk
USC3-10.750522971624-01-2L1
Nebraska3-20.600622801574-11-1W1

USC & Nebraska Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

USC Championship Odds
2025-26 USC NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
USC
+10000
Bet
Nebraska Championship Odds
2025-26 Nebraska NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Nebraska
+15000
Bet

USC & Nebraska Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 USC Games & Results
WeekMatchupDate & Result
Week 1Missouri State vs
USC
USC 73, MOST 13
Saturday, August 30th, 2025
Week 2Georgia Southern vs
USC
USC 59, GASO 20
Saturday, September 6th, 2025
Week 3USC vs
Purdue
USC 33, PUR 17
Saturday, September 13th, 2025
Week 4Michigan State vs
USC
USC 45, MSU 31
Saturday, September 20th, 2025
Week 5USC vs
Illinois
ILL 34, USC 32
Saturday, September 27th, 2025
Week 7Michigan vs
USC
USC 31, MICH 13
Saturday, October 11th, 2025
Week 8USC vs
Notre Dame
ND 34, USC 24
Saturday, October 18th, 2025
Week 10USC vs
Nebraska
Saturday, November 1st, 2025
7:30 pm EDT
Week 11Northwestern vs
USC
Friday, November 7th, 2025
9:00 pm EST
Week 12Iowa vs
USC
Saturday, November 15th, 2025
12:00 am EST
Week 13USC vs
Oregon
Saturday, November 22nd, 2025
12:00 am EST
Week 14UCLA vs
USC
Saturday, November 29th, 2025
12:00 am EST


2025-26 Nebraska Games & Results
WeekMatchupDate & Result
Week 1Nebraska vs
Cincinnati
NEB 20, CIN 17
Thursday, August 28th, 2025
Week 2Akron vs
Nebraska
NEB 68, AKR 0
Saturday, September 6th, 2025
Week 3Houston Christian vs
Nebraska
NEB 59, HCU 7
Saturday, September 13th, 2025
Week 4Michigan vs
Nebraska
MICH 30, NEB 27
Saturday, September 20th, 2025
Week 6Michigan State vs
Nebraska
NEB 38, MSU 27
Saturday, October 4th, 2025
Week 7Nebraska vs
Maryland
NEB 34, MD 31
Saturday, October 11th, 2025
Week 8Nebraska vs
Minnesota
MINN 24, NEB 6
Friday, October 17th, 2025
Week 9Northwestern vs
Nebraska
Saturday, October 25th, 2025
12:00 pm EDT
Week 10USC vs
Nebraska
Saturday, November 1st, 2025
7:30 pm EDT
Week 11Nebraska vs
UCLA
Saturday, November 8th, 2025
12:00 am EST
Week 13Nebraska vs
Penn State
Saturday, November 22nd, 2025
12:00 am EST
Week 14Iowa vs
Nebraska
Friday, November 28th, 2025
12:00 pm EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the USC vs Nebraska College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 1st, 2025 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the USC vs Nebraska Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the USC vs Nebraska Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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