Arizona vs Iowa State Football Odds

The Wildcats will play the Cyclones on Saturday, September 27th, 2025. The matchup takes place at Jack Trice Stadium. Watch this exciting Week 5 matchup at 7:00 pm EDT. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

We're now well into the 2025 college football season. Week 5 action features a matchup between Arizona and Iowa State taking place at Jack Trice Stadium. The following are some key season stats to help you size up this game.

  • SportsBetting3.com Power Rankings - Arizona has a 98.00 conference power ranking for the 2025 season. The conference power ranking for Iowa State is 97.00.
  • Away Arizona - Heading into Week 5, Arizona currently has a 0-0 record as an away team for the 2025 regular season. This ranks them 3rd in the Big 12 Conference for away team wins. Watch this stat carefully as the season progresses.
  • Home Iowa State - Iowa State has a 2-0 record as a home team. Looking ahead to this 2025 Week 5 matchup, they rank 2nd in the Big 12 Conference for home team wins. Like the Arizona away record and ranking, you should continually keep tabs on this stat.
  • Points Scored - For the 2025 season, Arizona ranks 9th (111) in the Big 12 Conference, with Iowa State currently ranking 8th (119) for points scored in the Big 12 Conference.
  • Points Against - Also in 2025, Arizona stands 13th (26) in the Big 12 Conference for points scored by opponents in 2025. Iowa State sits at 9th (57) in the Big 12 Conference for points against in the 2025 season so far.
  • Team Records - Arizona has a 3-0 overall record for the 2025 regular season, with Iowa State currently 4-0 for the 2025 NCAAF regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for a wild showdown between Arizona and Iowa State on September 27th!

The game will be held at the electric Jack Trice Stadium, home of the Cyclones.

According to SportsBetting3.com Power Rankings, Arizona has a slight edge over Iowa State.

Arizona is undefeated with a 3-0 record, while Iowa State boasts a perfect 4-0 standing.

Bet this game at BetRivers, or BetMGM and review this game's prop bets. Compare the odds below!

Best Wildcats at Cyclones Odds


Best Point Spread Betting Odds
Underdog

Arizona
Favorite

Iowa State
Iowa State has a -4.5 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. Arizona has a +4.5 -115 point spread at BetMGM OH. Arizona is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 48.5 points. Risk $110 to win $100. BetMGM has the best under line of 48.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Arizona
Favorite

Iowa State
Iowa State is the -190 moneyline favorite. Risk $190 to win $100 on Iowa State at BetMGM. Arizona is the +155 underdog at BetMGM. Risk $100 to win $155 on Arizona. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Arizona vs Iowa State College Football game on Saturday, September 27th, 2025?

Iowa State is a -4.5 -105 point spread favorite at BetMGM, while Arizona is a +4.5 -115 point spread underdog at BetMGM.

What is the over-under total line for the Arizona vs Iowa State College Football game on Saturday, September 27th, 2025?

The best over line is 48.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 48.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Arizona vs Iowa State College Football game on Saturday, September 27th, 2025?

Iowa State is a -190 moneyline favorite at BetMGM and Arizona is a +155 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Arizona
Iowa State
9/27/25 7:00pm EDT
+4.5 -115-4.5 -105
Bet $100 at BetMGM Ohio
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Underdog Arizona - Arizona bettors risk $100 to win $86.96 at -115 odds.

A +4.5 Arizona underdog bet wins if they lose by 4 or fewer, tie, or win outright. Your bet loses if they lose by 5 or more.

Favorite Iowa State - Iowa State bettors risk $100 to win $95.24 at -105 odds.

A -4.5 Iowa State favorite bet wins if they win by 5 or more. Your bet loses if they win by 4 or fewer, tie, or lose outright.

Arizona at Iowa State Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Arizona
Iowa State
No Touchdown
To Score 1st Touchdown
9/27/25 7:00pm EDT
+120-175+10000Bet
Arizona
Iowa State
Game to Overtime
9/27/25 7:00pm EDT
Yes +1050No -10000Bet
Arizona
Iowa State
Both Teams Score 10+
9/27/25 7:00pm EDT
Yes -900No +525Bet
Arizona
Iowa State
Both Teams Score 20+
9/27/25 7:00pm EDT
Yes -102No -125Bet
BetMGM Sports Betting BetMGM
Arizona
Iowa State
Both Teams Score 30+
9/27/25 7:00pm EDT
Yes +575No -1000Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 5
Arizona vs Iowa State
Saturday, September 27th, 2025
ISU 39, ARIZ 14
Jack Trice Stadium
Iowa State by 25

Team Standings

2025-2026 College Football Regular Season Standings - Arizona, Iowa State
Team Conf Conf% W L PF PA Home Away Strk
#22 Iowa State2-10.667511881093-01-1L1
Arizona1-10.50041166784-00-1W1

Arizona & Iowa State Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Arizona Championship Odds
2025-26 Arizona NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Arizona
+100000
Bet
Iowa State Championship Odds
2025-26 Iowa State NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Iowa State
+15000
Bet

Arizona & Iowa State Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Arizona Games & Results
WeekMatchupDate & Result
Week 1Hawaii vs
Arizona
ARIZ 40, HAW 6
Saturday, August 30th, 2025
Week 2Weber State vs
Arizona
ARIZ 48, WEB 3
Saturday, September 6th, 2025
Week 3Kansas State vs
Arizona
ARIZ 23, KSU 17
Friday, September 12th, 2025
Week 5Arizona vs
Iowa State
ISU 39, ARIZ 14
Saturday, September 27th, 2025
Week 6Oklahoma State vs
Arizona
ARIZ 41, OKST 13
Saturday, October 4th, 2025
Week 7BYU vs
Arizona
Saturday, October 11th, 2025
8:00 pm EDT
Week 8Arizona vs
Houston
Saturday, October 18th, 2025
12:00 pm EDT
Week 10Arizona vs
Colorado
Saturday, November 1st, 2025
12:00 am EDT
Week 11Kansas vs
Arizona
Saturday, November 8th, 2025
12:00 am EST
Week 12Arizona vs
Cincinnati
Saturday, November 15th, 2025
12:00 am EST
Week 13Baylor vs
Arizona
Saturday, November 22nd, 2025
12:00 am EST
Week 14Arizona vs
Arizona State
Friday, November 28th, 2025
12:00 am EST


2025-26 Iowa State Games & Results
WeekMatchupDate & Result
Week 1Iowa State vs
Kansas State
ISU 24, KSU 21
Saturday, August 23rd, 2025
Week 1South Dakota vs
Iowa State
ISU 55, SDAK 7
Saturday, August 30th, 2025
Week 2Iowa vs
Iowa State
ISU 16, IOWA 13
Saturday, September 6th, 2025
Week 3Iowa State vs
Arkansas State
ISU 24, ARST 16
Saturday, September 13th, 2025
Week 5Arizona vs
Iowa State
ISU 39, ARIZ 14
Saturday, September 27th, 2025
Week 6Iowa State vs
Cincinnati
CIN 38, ISU 30
Saturday, October 4th, 2025
Week 7Iowa State vs
Colorado
Saturday, October 11th, 2025
3:30 pm EDT
Week 9BYU vs
Iowa State
Saturday, October 25th, 2025
12:00 am EDT
Week 10Arizona State vs
Iowa State
Saturday, November 1st, 2025
12:00 am EDT
Week 11Iowa State vs
TCU
Saturday, November 8th, 2025
12:00 am EST
Week 13Kansas vs
Iowa State
Saturday, November 22nd, 2025
12:00 am EST
Week 14Iowa State vs
Oklahoma State
Saturday, November 29th, 2025
12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Arizona vs Iowa State College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 27th, 2025 at 7:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Arizona vs Iowa State Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Arizona vs Iowa State Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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