Eastern Michigan vs Buffalo Football Odds

The Eagles will play the Bulls on Saturday, October 4th, 2025. The matchup takes place at UB Stadium. Watch this exciting Week 6 matchup at 3:30 pm EDT. Check local listings for coverage on ESPN+.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

We're now well into the 2025 college football season. Week 6 action features a matchup between Eastern Michigan and Buffalo taking place at UB Stadium. The following are some key season stats to help you size up this game.

  • SportsBetting3.com Power Rankings - Eastern Michigan has a 95.67 conference power ranking for the 2025 season. The conference power ranking for Buffalo is 98.33.
  • Away Eastern Michigan - Heading into Week 6, Eastern Michigan currently has a 0-3 record as an away team for the 2025 regular season. This ranks them 2nd in the MAC Conference for away team wins. Watch this stat carefully as the season progresses.
  • Home Buffalo - Buffalo has a 1-2 record as a home team. Looking ahead to this 2025 Week 6 matchup, they rank 3rd in the MAC Conference for home team wins. Like the Eastern Michigan away record and ranking, you should continually keep tabs on this stat.
  • Points Scored - For the 2025 season, Eastern Michigan ranks 3rd (120) in the MAC Conference, with Buffalo currently ranking 3rd (120) for points scored in the MAC Conference.
  • Points Against - Also in 2025, Eastern Michigan stands 1st (183) in the MAC Conference for points scored by opponents in 2025. Buffalo sits at 11th (98) in the MAC Conference for points against in the 2025 season so far.
  • Team Records - Eastern Michigan has a 1-4 overall record for the 2025 regular season, with Buffalo currently 2-3 for the 2025 NCAAF regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for a wild showdown as Eastern Michigan faces off against Buffalo this Saturday!

UB Stadium will be the place to be as these two teams clash in Week 6.

Eastern Michigan sits at 1-4 while Buffalo holds a 2-3 record heading into this matchup.

According to SportsBetting3.com Power Rankings, Buffalo has a slight edge over Eastern Michigan. Bet this game at BetRivers, or BetMGM. Review this game's prop bets and compare the odds below.

Best Eagles at Bulls Odds


Best Point Spread Betting Odds
Underdog

Eastern Michigan
Favorite

Buffalo
Buffalo has a -10 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Eastern Michigan has a +10 -120 point spread at BetMGM OH. Eastern Michigan is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 53.5 points. Risk $115 to win $100. BetMGM has the best under line of 53.5 points. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Eastern Michigan
Favorite

Buffalo
Buffalo is the -350 moneyline favorite. Risk $350 to win $100 on Buffalo at BetMGM. Eastern Michigan is the +275 underdog at BetMGM. Risk $100 to win $275 on Eastern Michigan. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Eastern Michigan vs Buffalo College Football game on Saturday, October 4th, 2025?

Buffalo is a -10 -110 point spread favorite at BetMGM, while Eastern Michigan is a +10 -120 point spread underdog at BetMGM.

What is the over-under total line for the Eastern Michigan vs Buffalo College Football game on Saturday, October 4th, 2025?

The best over line is 53.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 53.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the moneyline for the Eastern Michigan vs Buffalo College Football game on Saturday, October 4th, 2025?

Buffalo is a -350 moneyline favorite at BetMGM and Eastern Michigan is a +275 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Eastern Michigan
Buffalo
10/04/25 3:30pm EDT
+10 -120-10 -110
Bet $100 at BetMGM Ohio
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Underdog Eastern Michigan - Eastern Michigan bettors risk $100 to win $83.33 at -120 odds.

A +10 Eastern Michigan underdog bet wins if they lose by 9 or fewer, tie, or win outright. The bet pushes if they lose by 10. Your bet loses if they lose by 11 or more.

Favorite Buffalo - Buffalo bettors risk $100 to win $90.91 at -110 odds.

A -10 Buffalo favorite bet wins if they win by 11 or more. The bet pushes if they win by 10. Your bet loses if they win by 9 or fewer, tie, or lose outright.

Eastern Michigan at Buffalo Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Eastern Michigan
Buffalo
No Touchdown
To Score 1st Touchdown
10/04/25 3:30pm EDT
+154-225+10000Bet
Eastern Michigan
Buffalo
Game to Overtime
10/04/25 3:30pm EDT
Yes +1250No -10000Bet
Eastern Michigan
Buffalo
Both Teams Score 10+
10/04/25 3:30pm EDT
Yes -1000No +550Bet
Eastern Michigan
Buffalo
Both Teams Score 20+
10/04/25 3:30pm EDT
Yes -125No -102Bet
BetMGM Sports Betting BetMGM
Eastern Michigan
Buffalo
Both Teams Score 30+
10/04/25 3:30pm EDT
Yes +450No -700Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 6
Eastern Michigan vs Buffalo
Saturday, October 4th, 2025
BUFF 31, EMU 30 (OT)
UB Stadium
Buffalo by 1
2024
Week 13
Buffalo vs Eastern Michigan
Wednesday, November 20th, 2024
BUFF 37, EMU 20
Rynearson Stadium
Buffalo by 17
2023
Week 13
Eastern Michigan vs Buffalo
Tuesday, November 21st, 2023
EMU 24, BUFF 11
UB Stadium
Eastern Michigan by 13
2022
Week 4
Buffalo vs Eastern Michigan
Saturday, September 24th, 2022
BUFF 50, EMU 31
Rynearson Stadium
Buffalo by 19

Team Standings

2025-2026 College Football Regular Season Standings - Eastern Michigan, Buffalo
Team Conf Conf% W L PF PA Home Away Strk
Buffalo2-01.000331511282-21-1W1
Eastern Michigan1-20.333251662242-10-4W1

Eastern Michigan & Buffalo Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Eastern Michigan Championship Odds

No NCAA College Football Championship TM Eastern Michigan YR: futures available

Buffalo Championship Odds

No NCAA College Football Championship TM Buffalo YR: futures available

Eastern Michigan & Buffalo Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Eastern Michigan Games & Results
WeekMatchupDate & Result
Week 1Eastern Michigan vs
Texas State
TXST 52, EMU 27
Saturday, August 30th, 2025
Week 2LIU vs
Eastern Michigan
LIU 28, EMU 23
Saturday, September 6th, 2025
Week 3Eastern Michigan vs
Kentucky
UK 48, EMU 23
Saturday, September 13th, 2025
Week 4Louisiana vs
Eastern Michigan
EMU 34, UL 31
Saturday, September 20th, 2025
Week 5Eastern Michigan vs
Central Michigan
CMU 24, EMU 13
Saturday, September 27th, 2025
Week 6Eastern Michigan vs
Buffalo
BUFF 31, EMU 30 (OT)
Saturday, October 4th, 2025
Week 7Northern Illinois vs
Eastern Michigan
EMU 16, NIU 10
Saturday, October 11th, 2025
Week 8Eastern Michigan vs
Miami (OH)
Saturday, October 18th, 2025
12:00 pm EDT
Week 9Ohio vs
Eastern Michigan
Saturday, October 25th, 2025
12:00 pm EDT
Week 11Bowling Green vs
Eastern Michigan
Saturday, November 8th, 2025
12:00 am EST
Week 12Eastern Michigan vs
Ball State
Saturday, November 15th, 2025
12:00 am EST
Week 14Western Michigan vs
Eastern Michigan
Tuesday, November 25th, 2025
12:00 am EST


2025-26 Buffalo Games & Results
WeekMatchupDate & Result
Week 1Buffalo vs
Minnesota
MINN 23, BUFF 10
Thursday, August 28th, 2025
Week 2St. Francis (PA) vs
Buffalo
BUFF 45, SFPA 6
Saturday, September 6th, 2025
Week 3Buffalo vs
Kent State
BUFF 31, KENT 28
Saturday, September 13th, 2025
Week 4Troy vs
Buffalo
TROY 21, BUFF 17
Saturday, September 20th, 2025
Week 5UConn vs
Buffalo
CONN 20, BUFF 17
Saturday, September 27th, 2025
Week 6Eastern Michigan vs
Buffalo
BUFF 31, EMU 30 (OT)
Saturday, October 4th, 2025
Week 8Buffalo vs
UMass
Saturday, October 18th, 2025
2:30 pm EDT
Week 9Akron vs
Buffalo
Saturday, October 25th, 2025
1:00 pm EDT
Week 10Buffalo vs
Bowling Green
Saturday, November 1st, 2025
12:00 am EDT
Week 12Buffalo vs
Central Michigan
Wednesday, November 12th, 2025
7:00 pm EST
Week 13Miami (OH) vs
Buffalo
Wednesday, November 19th, 2025
7:00 pm EST
Week 14Ohio vs
Buffalo
Friday, November 28th, 2025
12:00 pm EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Eastern Michigan vs Buffalo College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, October 4th, 2025 at 3:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Eastern Michigan vs Buffalo Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Eastern Michigan vs Buffalo Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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