Syracuse vs SMU Football Odds

The Orange will play the Mustangs on Saturday, October 4th, 2025. The matchup takes place at Gerald J. Ford Stadium. Watch this exciting Week 6 matchup at 3:30 pm EDT. Check local listings for coverage on ACC Network.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

We're now well into the 2025 college football season. Week 6 action features a matchup between Syracuse and SMU taking place at Gerald J. Ford Stadium. The following are some key season stats to help you size up this game.

  • SportsBetting3.com Power Rankings - Syracuse has a 93.33 conference power ranking for the 2025 season. The conference power ranking for SMU is 93.67.
  • Away Syracuse - Heading into Week 6, Syracuse currently has a 1-0 record as an away team for the 2025 regular season. This ranks them 2nd in the ACC Conference for away team wins. Watch this stat carefully as the season progresses.
  • Home SMU - SMU has a 1-1 record as a home team. Looking ahead to this 2025 Week 6 matchup, they rank 4th in the ACC Conference for home team wins. Like the Syracuse away record and ranking, you should continually keep tabs on this stat.
  • Points Scored - For the 2025 season, Syracuse ranks 6th (156) in the ACC Conference, with SMU currently ranking 10th (139) for points scored in the ACC Conference.
  • Points Against - Also in 2025, Syracuse stands 1st (148) in the ACC Conference for points scored by opponents in 2025. SMU sits at 7th (106) in the ACC Conference for points against in the 2025 season so far.
  • Team Records - Syracuse has a 3-2 overall record for the 2025 regular season, with SMU currently 2-2 for the 2025 NCAAF regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Are you ready for a wild matchup between Syracuse and SMU on October 4th?

Get ready for the Week 6 showdown at Gerald J. Ford Stadium - it's going to be epic!

Syracuse and SMU are neck and neck in the Power Rankings - this game could go either way.

With Syracuse at 3-2 and SMU at 2-2, anything can happen on Saturday.

Don't miss out on the action - bet this game at BetRivers, or BetMGM, review this game's prop bets, and compare the odds below.

Best Orange at Mustangs Odds


Best Point Spread Betting Odds
Underdog

Syracuse
Favorite

SMU
SMU has a -17.5 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. Syracuse has a +17.5 -115 point spread at BetMGM OH. Syracuse is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 58.5 points. Risk $110 to win $100. BetMGM has the best under line of 58.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Syracuse
Favorite

SMU
SMU is the -800 moneyline favorite. Risk $800 to win $100 on SMU at BetMGM. Syracuse is the +550 underdog at BetMGM. Risk $100 to win $550 on Syracuse. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Syracuse vs SMU College Football game on Saturday, October 4th, 2025?

SMU is a -17.5 -105 point spread favorite at BetMGM, while Syracuse is a +17.5 -115 point spread underdog at BetMGM.

What is the over-under total line for the Syracuse vs SMU College Football game on Saturday, October 4th, 2025?

The best over line is 58.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 58.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Syracuse vs SMU College Football game on Saturday, October 4th, 2025?

SMU is a -800 moneyline favorite at BetMGM and Syracuse is a +550 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Syracuse
SMU
10/04/25 3:30pm EDT
+17.5 -115-17.5 -105
Bet $100 at BetMGM Ohio
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Underdog Syracuse - Syracuse bettors risk $100 to win $86.96 at -115 odds.

A +17.5 Syracuse underdog bet wins if they lose by 17 or fewer, tie, or win outright. Your bet loses if they lose by 18 or more.

Favorite SMU - SMU bettors risk $100 to win $95.24 at -105 odds.

A -17.5 SMU favorite bet wins if they win by 18 or more. Your bet loses if they win by 17 or fewer, tie, or lose outright.

Syracuse at SMU Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Syracuse
SMU
No Touchdown
To Score 1st Touchdown
10/04/25 3:30pm EDT
+240-375+10000Bet
Syracuse
SMU
Game to Overtime
10/04/25 3:30pm EDT
Yes +1600No -10000Bet
Syracuse
SMU
Both Teams Score 10+
10/04/25 3:30pm EDT
Yes -900No +525Bet
Syracuse
SMU
Both Teams Score 20+
10/04/25 3:30pm EDT
Yes -130No +100Bet
BetMGM Sports Betting BetMGM
Syracuse
SMU
Both Teams Score 30+
10/04/25 3:30pm EDT
Yes +425No -650Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin

Team Standings

2025-2026 College Football Regular Season Standings - Syracuse, SMU
Team Conf Conf% W L PF PA Home Away Strk
Syracuse1-10.500321561482-11-0L1
SMU0-00.000221391061-11-1L1

Syracuse & SMU Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Syracuse Championship Odds
2025-26 Syracuse NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Syracuse
SMU Championship Odds
2025-26 SMU NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
SMU
+15000
Bet

Syracuse & SMU Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Syracuse Games & Results
WeekMatchupDate & Result
Week 1Syracuse vs
Tennessee
TENN 45, SYR 26
Saturday, August 30th, 2025
Week 2UConn vs
Syracuse
SYR 27, CONN 20 (OT)
Saturday, September 6th, 2025
Week 3Colgate vs
Syracuse
SYR 66, COLG 24
Friday, September 12th, 2025
Week 4Syracuse vs
Clemson
SYR 34, CLEM 21
Saturday, September 20th, 2025
Week 5Duke vs
Syracuse
DUKE 38, SYR 3
Saturday, September 27th, 2025
Week 6Syracuse vs
SMU
Saturday, October 4th, 2025
3:30 pm EDT
Week 8Pittsburgh vs
Syracuse
Saturday, October 18th, 2025
12:00 am EDT
Week 9Syracuse vs
Georgia Tech
Saturday, October 25th, 2025
12:00 am EDT
Week 10North Carolina vs
Syracuse
Friday, October 31st, 2025
7:30 pm EDT
Week 11Syracuse vs
Miami (FL)
Saturday, November 8th, 2025
12:00 am EST
Week 13Syracuse vs
Notre Dame
Saturday, November 22nd, 2025
3:30 pm EST
Week 14Boston College vs
Syracuse
Saturday, November 29th, 2025
12:00 am EST


2025-26 SMU Games & Results
WeekMatchupDate & Result
Week 1East Texas A&M vs
SMU
SMU 42, ETAM 13
Saturday, August 30th, 2025
Week 2Baylor vs
SMU
BAY 48, SMU 45 (2OT)
Saturday, September 6th, 2025
Week 3SMU vs
Missouri State
SMU 28, MOST 10
Saturday, September 13th, 2025
Week 4SMU vs
TCU
TCU 35, SMU 24
Saturday, September 20th, 2025
Week 6Syracuse vs
SMU
Saturday, October 4th, 2025
3:30 pm EDT
Week 7Stanford vs
SMU
Saturday, October 11th, 2025
12:00 pm EDT
Week 8SMU vs
Clemson
Saturday, October 18th, 2025
12:00 am EDT
Week 9SMU vs
Wake Forest
Saturday, October 25th, 2025
12:00 am EDT
Week 10Miami (FL) vs
SMU
Saturday, November 1st, 2025
12:00 am EDT
Week 11SMU vs
Boston College
Saturday, November 8th, 2025
12:00 am EST
Week 13Louisville vs
SMU
Saturday, November 22nd, 2025
12:00 am EST
Week 14SMU vs
California
Saturday, November 29th, 2025
12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Syracuse vs SMU College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, October 4th, 2025 at 3:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Syracuse vs SMU Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Syracuse vs SMU Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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