The Hawkeyes will play the Cyclones on Saturday, September 6th, 2025. The matchup takes place at Jack Trice Stadium. Watch this exciting Week 2 matchup at 12:00 pm EDT. Check local listings for coverage on FOX.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
The 2025 college football season continues with Iowa matching up against Iowa State at Jack Trice Stadium. Let's review how each team is doing so far to better understand how this game will play out.
- SportsBetting3.com Power Rankings - Iowa has a 98.00 conference power ranking for the 2025 season so far. The 2025 conference power ranking for Iowa State is 99.00.
- Away Iowa - Iowa currently has a 0-0 record as an away team for the 2025 regular season, ranking them 1st in the Big Ten Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
- Home Iowa State - So far, Iowa State has a 1-0 record as a home team. They currently rank 2nd in the Big 12 Conference for home team wins in 2025. Keep tabs on this figure, as it will change in the coming weeks.
- Points Scored - Iowa ranks 7th (34) in the Big Ten Conference, with Iowa State currently ranking 1st (79) for points scored in the 2025 Big 12 Conference.
- Points Against - Iowa stands 10th (7) in the Big Ten Conference for points scored by opponents in 2025. Iowa State sits at 3rd (28) in the 2025 Big 12 Conference for points against in the 2025 season.
- Team Records - Iowa has a 1-0 regular season overall record, with Iowa State currently possessing a 2-0 regular season standing for the 2025 NCAAF season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Get ready for a wild showdown at Jack Trice Stadium as Iowa takes on Iowa State.
Iowa State needs this win to stay perfect while Iowa looks to stay undefeated.
Check out SportsBetting3.com to review this game's prop bets and compare the odds below.
Best Hawkeyes at Cyclones Odds
| Underdog Iowa | Favorite Iowa State |
|---|---|
| Over | Under |
|---|---|
| Underdog Iowa | Favorite Iowa State |
|---|---|
Matchup Odds FAQs
Iowa State is a -3.5 -110 point spread favorite at BetMGM, while Iowa is a +3.5 -110 point spread underdog at BetMGM.
The best over line is 42.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 42.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
Iowa State is a -175 moneyline favorite at BetMGM and Iowa is a +145 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
Iowa
Iowa State
9/06/25 12:00pm EDT | +3.5 -110-3.5 -110 |
Underdog Iowa - Iowa bettors risk $100 to win $90.91 at -110 odds.
A +3.5 Iowa underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.
Favorite Iowa State - Iowa State bettors risk $100 to win $90.91 at -110 odds.
A -3.5 Iowa State favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.
Iowa at Iowa State Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Iowa
Iowa State
No Touchdown
To Score 1st Touchdown
9/06/25 12:00pm EDT | +110-160+10000Bet |
Iowa
Iowa State
Game to Overtime
9/06/25 12:00pm EDT | Yes +1050No -10000Bet |
Iowa
Iowa State
Both Teams Score 10+
9/06/25 12:00pm EDT | Yes -450No +310Bet |
Iowa
Iowa State
Both Teams Score 20+
9/06/25 12:00pm EDT | Yes +170No -220Bet |
| BetMGM | |
Iowa
Iowa State
Both Teams Score 30+
9/06/25 12:00pm EDT | Yes +1000No -3000Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 2 | Iowa vs Iowa State Saturday, September 6th, 2025 | ISU 16, IOWA 13 Jack Trice Stadium | Iowa State by 3 |
| 2024 Week 2 | Iowa State vs Iowa Saturday, September 7th, 2024 | ISU 20, IOWA 19 Kinnick Stadium | Iowa State by 1 |
| 2023 Week 2 | Iowa vs Iowa State Saturday, September 9th, 2023 | IOWA 20, ISU 13 Jack Trice Stadium | Iowa by 7 |
| 2022 Week 2 | Iowa State vs Iowa Saturday, September 10th, 2022 | ISU 10, IOWA 7 Kinnick Stadium | Iowa State by 3 |
| 2021 Week 2 | Iowa vs Iowa State Saturday, September 11th, 2021 | IOWA 27, ISU 17 Jack Trice Stadium | Iowa by 10 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| Big 12 | |||||||||
| #14 Iowa State | 1-0 | 1.000 | 4 | 0 | 119 | 57 | 2-0 | 1-0 | W4 |
| Big Ten | |||||||||
| Iowa | 0-0 | 0.000 | 2 | 1 | 94 | 30 | 2-0 | 0-1 | W1 |
Iowa & Iowa State Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Iowa Championship Odds|
Team | BetMGM |
|---|---|
| Iowa | +15000 Bet |
|
Team | BetMGM |
|---|---|
| Iowa State | +15000 Bet |
Iowa & Iowa State Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Albany vs Iowa | IOWA 34, ALB 7 Saturday, August 30th, 2025 |
| Week 2 | Iowa vs Iowa State | ISU 16, IOWA 13 Saturday, September 6th, 2025 |
| Week 3 | UMass vs Iowa | IOWA 47, MASS 7 Saturday, September 13th, 2025 |
| Week 4 | Iowa vs Rutgers | Friday, September 19th, 2025 8:00 pm EDT |
| Week 5 | Indiana vs Iowa | Saturday, September 27th, 2025 12:00 am EDT |
| Week 7 | Iowa vs Wisconsin | Saturday, October 11th, 2025 12:00 am EDT |
| Week 8 | Penn State vs Iowa | Saturday, October 18th, 2025 12:00 am EDT |
| Week 9 | Minnesota vs Iowa | Saturday, October 25th, 2025 12:00 am EDT |
| Week 11 | Oregon vs Iowa | Saturday, November 8th, 2025 12:00 am EST |
| Week 12 | Iowa vs USC | Saturday, November 15th, 2025 12:00 am EST |
| Week 13 | Michigan State vs Iowa | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | Iowa vs Nebraska | Friday, November 28th, 2025 12:00 pm EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Iowa State vs Kansas State | ISU 24, KSU 21 Saturday, August 23rd, 2025 |
| Week 1 | South Dakota vs Iowa State | ISU 55, SDAK 7 Saturday, August 30th, 2025 |
| Week 2 | Iowa vs Iowa State | ISU 16, IOWA 13 Saturday, September 6th, 2025 |
| Week 3 | Iowa State vs Arkansas State | ISU 24, ARST 16 Saturday, September 13th, 2025 |
| Week 5 | Arizona vs Iowa State | Saturday, September 27th, 2025 7:00 pm EDT |
| Week 6 | Iowa State vs Cincinnati | Saturday, October 4th, 2025 12:00 am EDT |
| Week 7 | Iowa State vs Colorado | Saturday, October 11th, 2025 12:00 am EDT |
| Week 9 | BYU vs Iowa State | Saturday, October 25th, 2025 12:00 am EDT |
| Week 10 | Arizona State vs Iowa State | Saturday, November 1st, 2025 12:00 am EDT |
| Week 11 | Iowa State vs TCU | Saturday, November 8th, 2025 12:00 am EST |
| Week 13 | Kansas vs Iowa State | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | Iowa State vs Oklahoma State | Saturday, November 29th, 2025 12:00 am EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Iowa vs Iowa State College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 6th, 2025 at 12:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Iowa vs Iowa State Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Iowa vs Iowa State Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 6, 2025 NCAAFB Games
- UConn vs Syracuse - 9/06/25 12:00pm EDT
- East Texas A&M vs Florida State - 9/06/25 12:00pm EDT
- FIU vs Penn State - 9/06/25 12:00pm EDT
- Kent State vs Texas Tech - 9/06/25 12:00pm EDT
- Liberty vs Jacksonville State - 9/06/25 12:00pm EDT
- Central Michigan vs Pittsburgh - 9/06/25 12:00pm EDT
- Northwestern State vs Minnesota - 9/06/25 12:00pm EDT
- Virginia vs NC State - 9/06/25 12:00pm EDT
- Illinois vs Duke - 9/06/25 12:00pm EDT
- Baylor vs SMU - 9/06/25 12:00pm EDT
- San Jose State vs Texas - 9/06/25 12:00pm EDT
- Kennesaw State vs Indiana - 9/06/25 12:00pm EDT
- Utah State vs Texas A&M - 9/06/25 12:45pm EDT
- Howard vs Temple - 9/06/25 2:00pm EDT
- Robert Morris vs Youngstown State - 9/06/25 2:00pm EDT
- Presbyterian vs Furman - 9/06/25 2:00pm EDT
- Western Carolina vs Wake Forest - 9/06/25 2:00pm EDT
- North Dakota State vs Tennessee State - 9/06/25 2:30pm EDT
- Idaho State vs New Mexico - 9/06/25 3:00pm EDT
- St. Francis (PA) vs Buffalo - 9/06/25 3:30pm EDT
- Oklahoma State vs Oregon - 9/06/25 3:30pm EDT
- Ole Miss vs Kentucky - 9/06/25 3:30pm EDT
- Kansas vs Missouri - 9/06/25 3:30pm EDT
- Miami (OH) vs Rutgers - 9/06/25 3:30pm EDT
- Austin Peay vs Georgia - 9/06/25 3:30pm EDT
- Troy vs Clemson - 9/06/25 3:30pm EDT
- Fresno State vs Oregon State - 9/06/25 3:30pm EDT
- North Texas vs Western Michigan - 9/06/25 3:30pm EDT
- Bowling Green vs Cincinnati - 9/06/25 3:30pm EDT
- Texas State vs UTSA - 9/06/25 3:30pm EDT
- East Tennessee State vs Tennessee - 9/06/25 3:30pm EDT
- Delaware vs Colorado - 9/06/25 3:30pm EDT
- UAB vs Navy - 9/06/25 3:30pm EDT
- West Virginia vs Ohio - 9/06/25 4:00pm EDT
- Middle Tennessee vs Wisconsin - 9/06/25 4:00pm EDT
- South Florida vs Florida - 9/06/25 4:15pm EDT
- Arkansas State vs Arkansas - 9/06/25 5:02pm EDT
- Bryant vs UMass - 9/06/25 5:30pm EDT
- Texas Southern vs California - 9/06/25 6:00pm EDT
- Missouri State vs Marshall - 9/06/25 6:00pm EDT
- Cal Poly vs Utah - 9/06/25 6:00pm EDT
- Campbell vs East Carolina - 9/06/25 6:00pm EDT
- Colgate vs Villanova - 9/06/25 6:00pm EDT
- Davidson vs Elon - 9/06/25 6:00pm EDT
- Florida A&M vs Florida Atlantic - 9/06/25 6:00pm EDT
- Houston Christian vs Eastern Kentucky - 9/06/25 6:00pm EDT
- Maine vs William & Mary - 9/06/25 6:00pm EDT
- North Carolina Central vs Old Dominion - 9/06/25 6:00pm EDT
- Rhode Island vs Stony Brook - 9/06/25 6:00pm EDT
- Richmond vs Wofford - 9/06/25 6:00pm EDT
- Holy Cross vs New Hampshire - 9/06/25 6:00pm EDT
- Alabama State vs Southern - 9/06/25 7:00pm EDT
- Bethune-Cookman vs Miami (FL) - 9/06/25 7:00pm EDT
- Alcorn State vs Alabama A&M - 9/06/25 7:00pm EDT
- South Dakota vs Lamar - 9/06/25 7:00pm EDT
- Arkansas-Pine Bluff vs Central Arkansas - 9/06/25 7:00pm EDT
- Southeastern Louisiana vs Murray State - 9/06/25 7:00pm EDT
- Portland State vs North Dakota - 9/06/25 7:00pm EDT
- North Alabama vs Southeast Missouri State - 9/06/25 7:00pm EDT
- Northern Colorado vs Colorado State - 9/06/25 7:00pm EDT
- Morehead State vs Illinois State - 9/06/25 7:00pm EDT
- Miss Valley State vs Tarleton - 9/06/25 7:00pm EDT
- North Carolina vs Charlotte - 9/06/25 7:00pm EDT
- Towson vs Morgan State - 9/06/25 7:00pm EDT
- West Georgia vs Nicholls - 9/06/25 7:00pm EDT
- LIU vs Eastern Michigan - 9/06/25 7:00pm EDT
- Western Kentucky vs Toledo - 9/06/25 7:00pm EDT
- Tulane vs South Alabama - 9/06/25 7:00pm EDT
- Houston vs Rice - 9/06/25 7:00pm EDT
- Memphis vs Georgia State - 9/06/25 7:00pm EDT
- Army vs Kansas State - 9/06/25 7:00pm EDT
- Charleston Southern vs Coastal Carolina - 9/06/25 7:30pm EDT
- Southern Illinois vs Purdue - 9/06/25 7:30pm EDT
- Ball State vs Auburn - 9/06/25 7:30pm EDT
- Boston College vs Michigan State - 9/06/25 7:30pm EDT
- Louisiana Tech vs LSU - 9/06/25 7:30pm EDT
- Arizona State vs Mississippi State - 9/06/25 7:30pm EDT
- Akron vs Nebraska - 9/06/25 7:30pm EDT
- Georgia Southern vs USC - 9/06/25 7:30pm EDT
- Michigan vs Oklahoma - 9/06/25 7:30pm EDT
- Vanderbilt vs Virginia Tech - 9/06/25 7:30pm EDT
- Louisiana-Monroe vs Alabama - 9/06/25 7:45pm EDT
- Stephen F. Austin vs Abilene Christian - 9/06/25 8:00pm EDT
- South Dakota State vs Montana State - 9/06/25 8:00pm EDT
- McNeese State vs Louisiana - 9/06/25 8:00pm EDT
- UCLA vs UNLV - 9/06/25 8:07pm EDT
- North Carolina A&T vs UCF - 9/06/25 8:10pm EDT
- South Carolina State vs South Carolina - 9/06/25 8:30pm EDT
- UT-Martin vs UTEP - 9/06/25 9:00pm EDT
- Southern Utah vs San Diego - 9/06/25 9:00pm EDT
- Tulsa vs New Mexico State - 9/06/25 9:05pm EDT
- Weber State vs Arizona - 9/06/25 10:00pm EDT
- Stanford vs BYU - 9/06/25 10:15pm EDT
- San Diego State vs Washington State - 9/06/25 10:15pm EDT
- UC Davis vs Washington - 9/06/25 11:00pm EDT