Arizona Cardinals vs San Francisco 49ers Odds

The Cardinals will play the 49ers on Sunday, October 6th, 2024. The matchup takes place at Levi's Stadium. Watch this exciting Week 5 matchup at 4:05 pm EDT. Check local listings for coverage on FOX.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Key Matchup Stats

The Arizona Cardinals and San Francisco 49ers will take the field at Levi's Stadium for a key Week 5 matchup on Sunday, October 6th, 2024. Have a look at each team's key performance stats below as they continue to make their way through the 2024-25 NFL regular season.

  • SportsBetting3.com Power Rankings - Heading into Week 5 of the 2024-25 season, the Arizona Cardinals have a power ranking of 91.00. Our calculations have the San Francisco 49ers at a 96.33 power ranking.
  • Away Arizona Cardinals - Now in the middle of the season, the Arizona Cardinals have a 0-1-0 record as an away team, ranking them 3rd in the league for away team wins.
  • Home San Francisco 49ers - The San Francisco 49ers come to this Week 5 matchup with a 2-0-0 record as a home team. They rank 1st in the league for home team wins so far this season.
  • Points Scored - The Arizona Cardinals currently rank 10th (96) on the edge of Week 5, with the San Francisco 49ers ranked 7th (103) for points scored to date.
  • Points Against - The Arizona Cardinals stand 4th (106) in the middle weeks of the regular season for points against. As for the San Francisco 49ers, they currently rank 16th (82) for points against.
  • Team Records - Standings become more important now more than ever. Approaching Week 5, the Arizona Cardinals have a 1-3-0 record, with the San Francisco 49ers at 2-2-0 for the 2024-25 regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye mateys! The Arizona Cardinals be sailing to San Francisco to plunder a victory.

The Red Birds be sittin' on a 1-3-0 record, while the 49ers be standin' at 2-2-0.

Mid-season battles be crucial for both crews to climb the NFL standings.

This clash be happenin' at Levi's Stadium, where the city be alive with football fervor.

Compare the NFL Power Rankings - Cardinals at 91.00, 49ers at 96.33.

Bet this game at BetMGM or our preferred sports betting partner BetRivers. Look at this game's prop bets and compare odds from partner sports betting sites. Arrr!

Best Cardinals at 49ers Odds


Best Point Spread Betting Odds
Underdog

Arizona Cardinals
Favorite

San Francisco 49ers
The San Francisco 49ers have a -7 -115 point spread at BetMGM OH. They are the point spread favorite in this matchup. The Arizona Cardinals have a +7 -105 point spread at BetMGM OH. The Arizona Cardinals are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 49 points. Risk $110 to win $100. BetMGM has the best under line of 49 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Arizona Cardinals
Favorite

San Francisco 49ers
The San Francisco 49ers are the -350 moneyline favorite. Risk $350 to win $100 on the San Francisco 49ers at BetMGM. The Arizona Cardinals are the +280 underdog at BetMGM. Risk $100 to win $280 on the Arizona Cardinals. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Arizona Cardinals vs San Francisco 49ers NFL game on Sunday, October 6th, 2024?

The San Francisco 49ers are -7 -115 point spread favorites at BetMGM, while the Arizona Cardinals are +7 -105 point spread underdogs at BetMGM.

What is the over-under total line for the Arizona Cardinals vs San Francisco 49ers NFL game on Sunday, October 6th, 2024?

The best over line is 49 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 49 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Arizona Cardinals vs San Francisco 49ers NFL game on Sunday, October 6th, 2024?

The San Francisco 49ers are the -350 moneyline favorite at BetMGM and the Arizona Cardinals are the +280 moneyline underdog at BetMGM.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Cardinals
49ers
10/06/24 4:05pm EDT
+7 -105-7 -115
Bet $100 at BetMGM Ohio
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Underdog Arizona Cardinals - Arizona Cardinals bettors risk $100 to win $95.24 at -105 odds.

A +7 Arizona Cardinals underdog bet wins if they lose by 6 or fewer, tie, or win outright. The bet pushes if they lose by 7. Your bet loses if they lose by 8 or more.

Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $86.96 at -115 odds.

A -7 San Francisco 49ers favorite bet wins if they win by 8 or more. The bet pushes if they win by 7. Your bet loses if they win by 6 or fewer, tie, or lose outright.

Arizona Cardinals at San Francisco 49ers Prop Bets

NFL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Cardinals
49ers
First Team To Score
10/06/24 4:05pm EDT
+140-185Bet
Cardinals
49ers
No Touchdown
To Score 1st Touchdown
10/06/24 4:05pm EDT
+170-250+10000Bet
Cardinals
49ers
Game to Overtime
10/06/24 4:05pm EDT
Yes +800No -3000Bet
Cardinals
49ers
Safety to be Scored
10/06/24 4:05pm EDT
Yes +1000No -3000Bet
BetMGM Sports Betting BetMGM
Brock Purdy
Total Passing Yards
ARI at SF
10/06/24 4:05pm EDT
265.5 o -115265.5 u -115Bet
Brock Purdy
Longest Passing Completion
ARI at SF
10/06/24 4:05pm EDT
38.5 o -11038.5 u -120Bet
Brock Purdy
Interceptions Thrown
ARI at SF
10/06/24 4:05pm EDT
0.5 o +1050.5 u -140Bet
Brock Purdy
Total Touchdown Passes
ARI at SF
10/06/24 4:05pm EDT
1.5 o -1651.5 u +125Bet
BetMGM Sports Betting BetMGM
Brock Purdy
Total Pass Completions
ARI at SF
10/06/24 4:05pm EDT
21.5 o -10521.5 u -130Bet
Chad Ryland
Total Kicking Points
ARI at SF
10/06/24 4:05pm EDT
6.5 o -1056.5 u -120Bet
Jake Moody
Total Kicking Points
ARI at SF
10/06/24 4:05pm EDT
8.5 o +1058.5 u -140Bet
Kyler Murray
Total Touchdown Passes
ARI at SF
10/06/24 4:05pm EDT
1.5 o +1101.5 u -150Bet
BetMGM Sports Betting BetMGM
Kyler Murray
Longest Passing Completion
ARI at SF
10/06/24 4:05pm EDT
35.5 o -12035.5 u -110Bet
Kyler Murray
Total Passing Yards
ARI at SF
10/06/24 4:05pm EDT
232.5 o -115232.5 u -115Bet
Kyler Murray
Total Pass Completions
ARI at SF
10/06/24 4:05pm EDT
22.5 o +10022.5 u -135Bet
Kyler Murray
Interceptions Thrown
ARI at SF
10/06/24 4:05pm EDT
0.5 o -1350.5 u +100Bet
BetMGM Sports Betting BetMGM
Matt Prater
Total Kicking Points
ARI at SF
10/06/24 4:05pm EDT
6.5 o -1056.5 u -130Bet

Recent Meetings Since 2020

Recent Meetings Since 2020
WeekGameResultMargin
2024
Week 5
Cardinals vs 49ers
Sunday, October 6th, 2024
ARI 24, SF 23
Levi's Stadium
Cardinals by 1
2023
Week 15
49ers vs Cardinals
Sunday, December 17th, 2023
SF 45, ARI 29
State Farm Stadium
49ers by 16
2023
Week 4
Cardinals vs 49ers
Sunday, October 1st, 2023
SF 35, ARI 16
Levi's Stadium
49ers by 19
2022
Week 18
Cardinals vs 49ers
Sunday, January 8th, 2023
SF 38, ARI 13
Levi's Stadium
49ers by 25
2022
Week 11
49ers vs Cardinals
Monday, November 21st, 2022
SF 38, ARI 10
Estadio Azteca
49ers by 28
2021
Week 9
Cardinals vs 49ers
Sunday, November 7th, 2021
ARI 31, SF 17
Levi's Stadium
Cardinals by 14
2021
Week 5
49ers vs Cardinals
Sunday, October 10th, 2021
ARI 17, SF 10
State Farm Stadium
Cardinals by 7
2020
Week 16
49ers vs Cardinals
Saturday, December 26th, 2020
SF 20, ARI 12
State Farm Stadium
49ers by 8
2020
Week 1
Cardinals vs 49ers
Sunday, September 13th, 2020
ARI 24, SF 20
Levi's Stadium
Cardinals by 4

Team Standings

2024-2025 NFL Regular Season Standings - Arizona Cardinals, San Francisco 49ers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
Arizona Cardinals3400.4291501782-2-01-2-02-0-01.0002-3-00.4001W2-3-0
San Francisco 49ers3400.4291801582-2-01-2-01-2-00.3331-3-00.2501L2-3-0

Arizona Cardinals & San Francisco 49ers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Arizona Cardinals Futures Odds
2024-25 Arizona Cardinals Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Cardinals
+10000
Bet
San Francisco 49ers Futures Odds
2024-25 San Francisco 49ers Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
49ers
+900
Bet

Arizona Cardinals & San Francisco 49ers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Arizona Cardinals vs San Francisco 49ers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, October 6th, 2024 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Arizona Cardinals vs San Francisco 49ers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Arizona Cardinals vs San Francisco 49ers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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