The Chargers will play the Bills on Sunday, November 29th, 2020. The matchup takes place at Highmark Stadium. Watch this exciting Week 12 matchup at 12:00 pm CST. Check local listings for coverage on CBS.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.

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Best Chargers at Bills Odds

**Best Point Spread Betting Odds**
TBD	TBD

Point Spread odds are updating, please check back soon.

**Best Total Betting Odds**
Over	Under

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**Best Moneyline Betting Odds**
TBD	TBD

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NFL Odds Example

NFL Odds and Outcomes Explained
Game	Book

Los Angeles Chargers at Buffalo Bills Prop Bets

NFL Prop Bets
+ Displays more odds
	BetMGM Bet
Chargers Bills 11/29/20 12:00pm CST	Pending BetMGM

Recent Meetings Since 2016

Recent Meetings Since 2016
Week	Game	Result	Margin
2023 Week 16	Bills vs Chargers Saturday, December 23rd, 2023	BUF 24, LAC 22 SoFi Stadium	Bills by 2
2020 Week 12	Chargers vs Bills Sunday, November 29th, 2020	BUF 27, LAC 17 Highmark Stadium	Bills by 10
2018 Week 2	Chargers vs Bills Sunday, September 16th, 2018	LAC 31, BUF 20 Highmark Stadium	Chargers by 11
2017 Week 11	Bills vs Chargers Sunday, November 19th, 2017	LAC 54, BUF 24 Dignity Health Sports Park	Chargers by 30

Team Standings

2020-2021 NFL Regular Season Standings - Los Angeles Chargers, Buffalo Bills
Team	W	L	T	Pct	PF	PA	Home	Away	Div	Div%	Conf	Conf%	Strk	L5
xz - Buffalo Bills	13	3	0	0.813	501	375	7-1-0	6-2-0	6-0-0	1.000	10-2-0	0.833	6W	5-0-0
Los Angeles Chargers	7	9	0	0.438	384	426	4-4-0	3-5-0	3-3-0	0.500	6-6-0	0.500	4W	4-1-0

Los Angeles Chargers & Buffalo Bills Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Los Angeles Chargers Futures Odds

2025-26 Los Angeles Chargers Super Bowl Odds
Team	BetMGM
Chargers	+2500 Bet

Buffalo Bills Futures Odds

2025-26 Buffalo Bills Super Bowl Odds
Team	BetMGM
Bills	+750 Bet

Los Angeles Chargers & Buffalo Bills Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Los Angeles Chargers vs Buffalo Bills NFL Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, November 29th, 2020 at 12:00 pm CST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's NFL page, look for the Los Angeles Chargers vs Buffalo Bills Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Los Angeles Chargers vs Buffalo Bills Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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Los Angeles Chargers vs Buffalo Bills Odds

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