Iowa State vs Cincinnati Football Odds

The Cyclones will play the Bearcats on Saturday, October 4th, 2025. The matchup takes place at Nippert Stadium. Watch this exciting Week 6 matchup at 12:00 pm EDT. Check local listings for coverage on ESPN2.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

We're now well into the 2025 college football season. Week 6 action features a matchup between Iowa State and Cincinnati taking place at Nippert Stadium. The following are some key season stats to help you size up this game.

  • SportsBetting3.com Power Rankings - Iowa State has a 99.00 conference power ranking for the 2025 season. The conference power ranking for Cincinnati is 97.00.
  • Away Iowa State - Heading into Week 6, Iowa State currently has a 1-0 record as an away team for the 2025 regular season. This ranks them 3rd in the Big 12 Conference for away team wins. Watch this stat carefully as the season progresses.
  • Home Cincinnati - Cincinnati has a 2-0 record as a home team. Looking ahead to this 2025 Week 6 matchup, they rank 2nd in the Big 12 Conference for home team wins. Like the Iowa State away record and ranking, you should continually keep tabs on this stat.
  • Points Scored - For the 2025 season, Iowa State ranks 4th (158) in the Big 12 Conference, with Cincinnati currently ranking 4th (158) for points scored in the Big 12 Conference.
  • Points Against - Also in 2025, Iowa State stands 11th (71) in the Big 12 Conference for points scored by opponents in 2025. Cincinnati sits at 9th (74) in the Big 12 Conference for points against in the 2025 season so far.
  • Team Records - Iowa State has a 5-0 overall record for the 2025 regular season, with Cincinnati currently 3-1 for the 2025 NCAAF regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for a wild showdown as Iowa State marches into Cincinnati for a fierce battle.

Nippert Stadium will be rocking as Iowa State looks to maintain their perfect record.

Iowa State holds a slight edge over Cincinnati in the SportsBetting3.com Power Rankings.

With a 5-0 record, Iowa State is on fire, while Cincinnati sits at 3-1.

Bet this game at BetRivers, or BetMGM, review this game's prop bets, and compare the odds below.

Best Cyclones at Bearcats Odds


Best Point Spread Betting Odds
Underdog

Iowa State
Favorite

Cincinnati
Cincinnati has a -1.5 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Iowa State has a +1.5 -110 point spread at BetMGM OH. Iowa State is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 56.5 points. Risk $110 to win $100. BetMGM has the best under line of 56.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Iowa State
Favorite

Cincinnati
Cincinnati is the -120 moneyline favorite. Risk $120 to win $100 on Cincinnati at BetMGM. Iowa State is the +100 underdog at BetMGM. Risk $100 to win $100 on Iowa State. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Iowa State vs Cincinnati College Football game on Saturday, October 4th, 2025?

Cincinnati is a -1.5 -110 point spread favorite at BetMGM, while Iowa State is a +1.5 -110 point spread underdog at BetMGM.

What is the over-under total line for the Iowa State vs Cincinnati College Football game on Saturday, October 4th, 2025?

The best over line is 56.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 56.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Iowa State vs Cincinnati College Football game on Saturday, October 4th, 2025?

Cincinnati is a -120 moneyline favorite at BetMGM and Iowa State is a +100 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Iowa State
Cincinnati
10/04/25 12:00pm EDT
+1.5 -110-1.5 -110
Bet $100 at BetMGM Ohio
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Underdog Iowa State - Iowa State bettors risk $100 to win $90.91 at -110 odds.

A +1.5 Iowa State underdog bet wins if they lose by 1, tie, or win outright. Your bet loses if they lose by 2 or more.

Favorite Cincinnati - Cincinnati bettors risk $100 to win $90.91 at -110 odds.

A -1.5 Cincinnati favorite bet wins if they win by 2 or more. Your bet loses if they win by 1, tie, or lose outright.

Iowa State at Cincinnati Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Iowa State
Cincinnati
No Touchdown
To Score 1st Touchdown
10/04/25 12:00pm EDT
+100-145+10000Bet
Iowa State
Cincinnati
Game to Overtime
10/04/25 12:00pm EDT
Yes +950No -5000Bet
Iowa State
Cincinnati
Both Teams Score 10+
10/04/25 12:00pm EDT
Yes -2500No +900Bet
Iowa State
Cincinnati
Both Teams Score 20+
10/04/25 12:00pm EDT
Yes -210No +160Bet
BetMGM Sports Betting BetMGM
Iowa State
Cincinnati
Both Teams Score 30+
10/04/25 12:00pm EDT
Yes +280No -375Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2024
Week 12
Cincinnati vs Iowa State
Saturday, November 16th, 2024
ISU 34, CIN 17
Jack Trice Stadium
Iowa State by 17
2023
Week 7
Iowa State vs Cincinnati
Saturday, October 14th, 2023
ISU 30, CIN 10
Nippert Stadium
Iowa State by 20

Team Standings

2025-2026 College Football Regular Season Standings - Iowa State, Cincinnati
Team Conf Conf% W L PF PA Home Away Strk
Cincinnati1-01.00031158742-01-0W3
#14 Iowa State2-01.00050158713-01-0W5

Iowa State & Cincinnati Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Iowa State Championship Odds
2025-26 Iowa State NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Iowa State
+15000
Bet
Cincinnati Championship Odds
2025-26 Cincinnati NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Cincinnati
+100000
Bet

Iowa State & Cincinnati Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Iowa State Games & Results
WeekMatchupDate & Result
Week 1Iowa State vs
Kansas State
ISU 24, KSU 21
Saturday, August 23rd, 2025
Week 1South Dakota vs
Iowa State
ISU 55, SDAK 7
Saturday, August 30th, 2025
Week 2Iowa vs
Iowa State
ISU 16, IOWA 13
Saturday, September 6th, 2025
Week 3Iowa State vs
Arkansas State
ISU 24, ARST 16
Saturday, September 13th, 2025
Week 5Arizona vs
Iowa State
ISU 39, ARIZ 14
Saturday, September 27th, 2025
Week 6Iowa State vs
Cincinnati
Saturday, October 4th, 2025
12:00 pm EDT
Week 7Iowa State vs
Colorado
Saturday, October 11th, 2025
3:30 pm EDT
Week 9BYU vs
Iowa State
Saturday, October 25th, 2025
12:00 am EDT
Week 10Arizona State vs
Iowa State
Saturday, November 1st, 2025
12:00 am EDT
Week 11Iowa State vs
TCU
Saturday, November 8th, 2025
12:00 am EST
Week 13Kansas vs
Iowa State
Saturday, November 22nd, 2025
12:00 am EST
Week 14Iowa State vs
Oklahoma State
Saturday, November 29th, 2025
12:00 am EST


2025-26 Cincinnati Games & Results
WeekMatchupDate & Result
Week 1Nebraska vs
Cincinnati
NEB 20, CIN 17
Thursday, August 28th, 2025
Week 2Bowling Green vs
Cincinnati
CIN 34, BGSU 20
Saturday, September 6th, 2025
Week 3Northwestern State vs
Cincinnati
CIN 70, NWST 0
Saturday, September 13th, 2025
Week 5Cincinnati vs
Kansas
CIN 37, KU 34
Saturday, September 27th, 2025
Week 6Iowa State vs
Cincinnati
Saturday, October 4th, 2025
12:00 pm EDT
Week 7UCF vs
Cincinnati
Saturday, October 11th, 2025
12:00 pm EDT
Week 8Cincinnati vs
Oklahoma State
Saturday, October 18th, 2025
12:00 am EDT
Week 9Baylor vs
Cincinnati
Saturday, October 25th, 2025
12:00 am EDT
Week 10Cincinnati vs
Utah
Saturday, November 1st, 2025
12:00 am EDT
Week 12Arizona vs
Cincinnati
Saturday, November 15th, 2025
12:00 am EST
Week 13BYU vs
Cincinnati
Saturday, November 22nd, 2025
12:00 am EST
Week 14Cincinnati vs
TCU
Saturday, November 29th, 2025
12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Iowa State vs Cincinnati College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, October 4th, 2025 at 12:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Iowa State vs Cincinnati Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Iowa State vs Cincinnati Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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