UConn vs Buffalo Football Odds

The Huskies will play the Bulls on Saturday, September 27th, 2025. The matchup takes place at UB Stadium. Watch this exciting Week 5 matchup at 3:30 pm EDT. Check local listings for coverage on ESPN+.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

We're now well into the 2025 college football season. Week 5 action features a matchup between UConn and Buffalo taking place at UB Stadium. The following are some key season stats to help you size up this game.

  • SportsBetting3.com Power Rankings - UConn has a 99.33 conference power ranking for the 2025 season. The conference power ranking for Buffalo is 99.33.
  • Away UConn - Heading into Week 5, UConn currently has a 0-2 record as an away team for the 2025 regular season. This ranks them 2nd in the Independent Conference for away team wins. Watch this stat carefully as the season progresses.
  • Home Buffalo - Buffalo has a 1-1 record as a home team. Looking ahead to this 2025 Week 5 matchup, they rank 2nd in the MAC Conference for home team wins. Like the UConn away record and ranking, you should continually keep tabs on this stat.
  • Points Scored - For the 2025 season, UConn ranks 1st (151) in the Independent Conference, with Buffalo currently ranking 4th (103) for points scored in the MAC Conference.
  • Points Against - Also in 2025, UConn stands 1st (109) in the Independent Conference for points scored by opponents in 2025. Buffalo sits at 9th (78) in the MAC Conference for points against in the 2025 season so far.
  • Team Records - UConn has a 2-2 overall record for the 2025 regular season, with Buffalo currently 2-2 for the 2025 NCAAF regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Top o' the mornin' to ya, lads and lasses! UConn clashes with Buffalo in a fierce showdown!

Get ready for a wild time at UB Stadium as these two teams battle it out.

According to SportsBetting3.com, both UConn and Buffalo have a Power Ranking of 99.33 each.

UConn and Buffalo both enter this game with a 2-2 record, making this matchup crucial.

Don't miss out on the action - bet this game at BetRivers or BetMGM, review this game's prop bets, and compare the odds below to make your picks!

Best Huskies at Bulls Odds


Best Point Spread Betting Odds
Underdog

Buffalo
Favorite

UConn
UConn has a -3.5 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. Buffalo has a +3.5 -115 point spread at BetMGM OH. Buffalo is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 50.5 points. Risk $115 to win $100. BetMGM has the best under line of 50.5 points. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Buffalo
Favorite

UConn
UConn is the -160 moneyline favorite. Risk $160 to win $100 on UConn at BetMGM. Buffalo is the +135 underdog at BetMGM. Risk $100 to win $135 on Buffalo. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the UConn vs Buffalo College Football game on Saturday, September 27th, 2025?

UConn is a -3.5 -105 point spread favorite at BetMGM, while Buffalo is a +3.5 -115 point spread underdog at BetMGM.

What is the over-under total line for the UConn vs Buffalo College Football game on Saturday, September 27th, 2025?

The best over line is 50.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 50.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the moneyline for the UConn vs Buffalo College Football game on Saturday, September 27th, 2025?

UConn is a -160 moneyline favorite at BetMGM and Buffalo is a +135 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
UConn
Buffalo
9/27/25 3:30pm EDT
-3.5 -105+3.5 -115
Bet $100 at BetMGM Ohio
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Underdog Buffalo - Buffalo bettors risk $100 to win $86.96 at -115 odds.

A +3.5 Buffalo underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.

Favorite UConn - UConn bettors risk $100 to win $95.24 at -105 odds.

A -3.5 UConn favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.

UConn at Buffalo Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
UConn
Buffalo
No Touchdown
To Score 1st Touchdown
9/27/25 3:30pm EDT
-145+100+10000Bet
UConn
Buffalo
Game to Overtime
9/27/25 3:30pm EDT
Yes +950No -5000Bet
UConn
Buffalo
Both Teams Score 10+
9/27/25 3:30pm EDT
Yes -1100No +600Bet
UConn
Buffalo
Both Teams Score 20+
9/27/25 3:30pm EDT
Yes -120No -105Bet
BetMGM Sports Betting BetMGM
UConn
Buffalo
Both Teams Score 30+
9/27/25 3:30pm EDT
Yes +475No -750Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 5
UConn vs Buffalo
Saturday, September 27th, 2025
CONN 20, BUFF 17
UB Stadium
UConn by 3
2024
Week 5
Buffalo vs UConn
Saturday, September 28th, 2024
CONN 47, BUFF 3
Pratt & Whitney Stadium
UConn by 44

Team Standings

2025-2026 College Football Regular Season Standings - UConn, Buffalo
Team Conf Conf% W L PF PA Home Away Strk
Independent
UConn0-00.000422221363-01-2W3
MAC
Buffalo2-01.000331511282-21-1W1

UConn & Buffalo Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

UConn Championship Odds
2025-26 UConn NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
UConn
+100000
Bet
Buffalo Championship Odds
2025-26 Buffalo NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Buffalo

UConn & Buffalo Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 UConn Games & Results
WeekMatchupDate & Result
Week 1Central Connecticut vs
UConn
CONN 59, CCSU 13
Saturday, August 30th, 2025
Week 2UConn vs
Syracuse
SYR 27, CONN 20 (OT)
Saturday, September 6th, 2025
Week 3UConn vs
Delaware
DEL 44, CONN 41 (OT)
Saturday, September 13th, 2025
Week 4Ball State vs
UConn
CONN 31, BALL 25
Saturday, September 20th, 2025
Week 5UConn vs
Buffalo
CONN 20, BUFF 17
Saturday, September 27th, 2025
Week 6FIU vs
UConn
CONN 51, FIU 10
Saturday, October 4th, 2025
Week 8UConn vs
Boston College
Saturday, October 18th, 2025
12:00 pm EDT
Week 9UConn vs
Rice
Saturday, October 25th, 2025
12:00 am EDT
Week 10UAB vs
UConn
Saturday, November 1st, 2025
12:00 pm EDT
Week 11Duke vs
UConn
Saturday, November 8th, 2025
3:30 pm EST
Week 12Air Force vs
UConn
Saturday, November 15th, 2025
12:00 pm EST
Week 13UConn vs
Florida Atlantic
Saturday, November 22nd, 2025
12:00 am EST


2025-26 Buffalo Games & Results
WeekMatchupDate & Result
Week 1Buffalo vs
Minnesota
MINN 23, BUFF 10
Thursday, August 28th, 2025
Week 2St. Francis (PA) vs
Buffalo
BUFF 45, SFPA 6
Saturday, September 6th, 2025
Week 3Buffalo vs
Kent State
BUFF 31, KENT 28
Saturday, September 13th, 2025
Week 4Troy vs
Buffalo
TROY 21, BUFF 17
Saturday, September 20th, 2025
Week 5UConn vs
Buffalo
CONN 20, BUFF 17
Saturday, September 27th, 2025
Week 6Eastern Michigan vs
Buffalo
BUFF 31, EMU 30 (OT)
Saturday, October 4th, 2025
Week 8Buffalo vs
UMass
Saturday, October 18th, 2025
2:30 pm EDT
Week 9Akron vs
Buffalo
Saturday, October 25th, 2025
12:00 am EDT
Week 10Buffalo vs
Bowling Green
Saturday, November 1st, 2025
12:00 am EDT
Week 12Buffalo vs
Central Michigan
Wednesday, November 12th, 2025
7:00 pm EST
Week 13Miami (OH) vs
Buffalo
Wednesday, November 19th, 2025
7:00 pm EST
Week 14Ohio vs
Buffalo
Friday, November 28th, 2025
12:00 pm EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the UConn vs Buffalo College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 27th, 2025 at 3:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the UConn vs Buffalo Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the UConn vs Buffalo Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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