The Mets will play the Red Sox on Wednesday, May 21st, 2025. Your timezone's first pitch time is 6:45 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - As the 2025 season continues, the New York Mets possess a 96.00 SportsBetting3.com power ranking. The Boston Red Sox now have a 93.00 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
- Visiting New York Mets - The New York Mets head into this matchup with a 12-15 record as a visiting team. This standing ranks them 3rd Overall for visiting team wins.
- Home Boston Red Sox - The Boston Red Sox will throw the first pitch possessing a 14-11 home team record. That puts them 4th for home team wins in the Overall MLB standings.
- Runs Scored - New York Mets batters have produced 213 runs, ranking them 12th Overall, with the Boston Red Sox ranking 6th (239) for runs scored.
- Runs Allowed - New York Mets pitchers and fielders have allowed 161 runs, ranking them 25th Overall for runs allowed. Meanwhile, the Boston Red Sox now rank 7th Overall, allowing 227 runs.
- Team Streaks - The New York Mets have lost their last 3 games. Their opponent, the Boston Red Sox have won their last 2 games.
- Team Records - Let's review each team's records. The New York Mets have a 29-20 Overall record (1.5 GB National East Division), with the Boston Red Sox notching a 25-25 Overall standing (4.5 GB American East Division).
Captain Shady Lines
A broken compass is right at least twice a day.

Avast ye scallywags! The Mets be facin' off against the Red Sox...
Ye Mets be comin' in strong with a winnin' record, but barely holdin' on...
The Red Sox may be at home, but they be middlin' at best...
This be one match ye won't want to miss, so bet on it...
Check out this game's prop bets below and place yer wagers...
(But remember, always gamble responsibly, ya hear?)...
Review each team's standing at the bottom of the page, and may the best team win!
Best Mets at Red Sox Odds
Underdog New York Mets | Favorite Boston Red Sox |
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Over | Under |
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Underdog New York Mets | Favorite Boston Red Sox |
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Matchup Odds FAQs
The Boston Red Sox are the -150 moneyline favorite at BetMGM and the New York Mets are the +125 moneyline underdog at BetMGM.
The best over line is 7.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 7.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.
The Boston Red Sox are -1.5 +150 run line favorites at BetMGM, while the New York Mets are +1.5 -185 run line underdogs at BetMGM.
MLB Odds Example
Game |
![]() Bet |
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Mets
Red Sox
5/21/25 6:45pm EDT | +125-150 |
- New York Mets bettors risk $100 to win $125 at +125 odds. The implied probability for New York Mets is 44.44%.
- Boston Red Sox bettors risk $100 to win $66.67 at -150 odds. The implied probability for Boston Red Sox is 60%.
New York Mets at Boston Red Sox Prop Bets
![]() Bet |
|
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Mets
Red Sox
First Team to Score
5/21/25 6:45pm EDT | -120-105Bet |
Mets
Red Sox
Tie
1st Inning Winner
5/21/25 6:45pm EDT | +375+290-160Bet |
Mets
Red Sox
Tie
First 3 Innings Winner
5/21/25 6:45pm EDT | +195+120+240Bet |
Mets
Red Sox
To Extra Innings
5/21/25 6:45pm EDT | Yes +700No -1100Bet |
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Mets
Red Sox
1st Team to Score Will Win
5/21/25 6:45pm EDT | Yes -250No +190Bet |
Red Sox
Total Runs
NYM at BOS 5/21/25 6:45pm EDT | 3.5 o -1453.5 u +110Bet |
Mets
Total Runs
NYM at BOS 5/21/25 6:45pm EDT | 3.5 o +1003.5 u -130Bet |
Garrett Crochet
Strikeouts Thrown
NYM at BOS 5/21/25 6:45pm EDT | 7.5 o +1107.5 u -145Bet |
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Tylor Megill
Strikeouts Thrown
NYM at BOS 5/21/25 6:45pm EDT | 5.5 o -1455.5 u +110Bet |
New York Mets & Boston Red Sox Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
New York Mets World Series Odds
Team | ![]() |
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Mets | +800 Bet |
Team | ![]() |
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Red Sox | +5000 Bet |
New York Mets & Boston Red Sox Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
---|---|---|---|---|---|---|---|---|---|---|---|
New York Mets | 33 | 21 | 0.611 | +2.0 | 20-6 | 13-15 | 233 | 173 | +60 | W3 | 5-5 |
Boston Red Sox | 27 | 29 | 0.482 | +9.0 | 16-14 | 11-15 | 269 | 252 | +17 | L3 | 5-5 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the New York Mets vs Boston Red Sox MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, May 21st, 2025 at 6:45 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the New York Mets vs Boston Red Sox Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the New York Mets vs Boston Red Sox Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other May 21, 2025 MLB Games
- Cincinnati Reds vs Pittsburgh Pirates
- Baltimore Orioles vs Milwaukee Brewers
- Chicago Cubs vs Miami Marlins
- Houston Astros vs Tampa Bay Rays
- Detroit Tigers vs St. Louis Cardinals
- Seattle Mariners vs Chicago White Sox
- Cleveland Guardians vs Minnesota Twins
- Kansas City Royals vs San Francisco Giants
- Atlanta Braves vs Washington Nationals
- Texas Rangers vs New York Yankees
- San Diego Padres vs Toronto Blue Jays
- Cleveland Guardians vs Minnesota Twins
- Philadelphia Phillies vs Colorado Rockies
- Los Angeles Angels vs Oakland Athletics
- Arizona Diamondbacks vs Los Angeles Dodgers