Oregon vs USC Basketball Odds

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The Ducks will play the Trojans on Saturday, February 21st, 2026. Your timezone's tip off time is 4:00 pm EST. Check local listings or your nearest streaming app for coverage.

Review our College Basketball Betting guide to learn how to bet this game.


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Table of Contents

Key Matchup Stats

Looking into the second half of the 2025-26 college basketball season, Oregon and USC are set to hit the hardwood on Saturday, February 21st, 2026. Luckily, we have some clear performance trends emerging now that each team has more than a dozen games under their belts. Use the following data to help analyze this matchup and to place an intelligent wager on its ultimate outcome.

  • SportsBetting3.com Power Rankings - With the 2025-26 season in full stride, Oregon currently has a 91.33 conference power ranking, while the SportsBetting3.com conference power ranking for USC is 95.00.
  • Away Oregon - Oregon starts this game with a 1-6 record as an away team, ranking them 8th in the Big Ten Conference for away team wins.
  • Home USC - USC meets Oregon boasting a 9-4 record as a home team. They currently rank 6th in the Big Ten Conference for home team wins.
  • Conference Win Percentage - Oregon currently ranks 12th (0.133) in the Big Ten Conference, with USC now standing 7th (0.467) for their conference win percentage in the 2025 Big Ten Conference for the 2025-26 college basketball season.
  • Overall Win Percentage - Oregon has a 0.346 overall win percentage, with USC matching up with a 0.692 overall win percentage.
  • Team Records - Oregon currently possesses 9-17 regular season overall record. Meanwhile, USC has tallied a 18-8 standing as the 2025-26 college basketball season continues to unfold.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Moneyline Mage
Moneyline Mage

Gather 'round, my fellow wizards, as Oregon clashes with USC this Saturday!

Oregon, 9-17 overall, battles USC, 18-8 overall, in a crucial conference showdown.

In the Big Ten, Oregon at 2-13 faces USC at 7-8. Review the tables below to find the best point spread, total, and moneylines for this game. The outcome will heavily impact conference tournament seeding. Oregon has a losing streak, while USC has dropped their last 2 games. You can bet on college basketball legally at BetRivers and BetMGM. We've also listed each team's futures odds and current standings below. May the best team prevail on the court come Saturday!

Best Ducks at Trojans Odds


Best Point Spread Betting Odds
Underdog

Oregon		Favorite

USC
+5.5 -115 BetMGM
Bet
-5.5 -105 BetMGM
Bet
USC has a -5.5 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. Oregon has a +5.5 -115 point spread at BetMGM OH. Oregon is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
147.5 o -110 BetMGM
Bet
147.5 u -110 BetMGM
Bet
BetMGM has the best over line of 147.5 points. Risk $110 to win $100. BetMGM has the best under line of 147.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Oregon		Favorite

USC
+185 BetMGM
Bet
-225 BetMGM
Bet
USC is the -225 moneyline favorite. Risk $225 to win $100 on USC at BetMGM. Oregon is the +185 underdog at BetMGM. Risk $100 to win $185 on Oregon. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Oregon vs USC College Basketball game on Saturday, February 21st, 2026?

USC is a -5.5 -105 point spread favorite at BetMGM, while Oregon is a +5.5 -115 point spread underdog at BetMGM.

What is the over-under total line for the Oregon vs USC College Basketball game on Saturday, February 21st, 2026?

The best over line is 147.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 147.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Oregon vs USC College Basketball game on Saturday, February 21st, 2026?

USC is a -225 moneyline favorite at BetMGM and Oregon is a +185 moneyline underdog at BetMGM.

College Basketball Odds Example

College Basketball Odds and Outcomes Explained

Game		 BetMGM Sports Betting BetMGM
Bet
Oregon
USC
2/21/26 4:00pm EST
+5.5 -115-5.5 -105
Bet $100 at BetMGM Ohio
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Underdog Oregon - Oregon bettors risk $100 to win $86.96 at -115 odds.

A +5.5 Oregon underdog bet wins if they lose by 5 or fewer, tie, or win outright. Your bet loses if they lose by 6 or more.

Favorite USC - USC bettors risk $100 to win $95.24 at -105 odds.

A -5.5 USC favorite bet wins if they win by 6 or more. Your bet loses if they win by 5 or fewer, tie, or lose outright.

Oregon at USC Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Basketball Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Oregon
USC
First to 5 Points
2/21/26 4:00pm EST
+100-140Bet
Oregon
USC
First to 10 Points
2/21/26 4:00pm EST
+110-155Bet
Oregon
USC
First to 15 Points
2/21/26 4:00pm EST
+115-160Bet
Oregon
USC
Game to Overtime
2/21/26 4:00pm EST
Yes +825No -3000Bet

Team Standings

2025-2026 College Basketball Regular Season Standings - Oregon, USC
Team W-L Win% Home Away Conf CGB Conf% Strk
USC18-140.5639-75-67-13+120.350L8
Oregon12-200.37510-72-85-15+140.250L1

Oregon & USC Futures Odds

Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.

Oregon Championship Odds

No NCAA Men's Basketball Tournament TM Oregon YR: futures available

USC Championship Odds

No NCAA Men's Basketball Tournament TM USC YR: futures available

Oregon & USC Team Pages

Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Oregon vs USC College Basketball Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, February 21st, 2026 at 4:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Basketball page, look for the Oregon vs USC Game.

    Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the Oregon vs USC Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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