Southern Indiana vs Eastern Illinois Basketball Odds

The Screaming Eagles will play the Panthers on Saturday, February 21st, 2026. Your timezone's tip off time is 4:30 pm EST. Check local listings or your nearest streaming app for coverage.

Review our College Basketball Betting guide to learn how to bet this game.


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Table of Contents

Key Matchup Stats

Looking into the second half of the 2025-26 college basketball season, Southern Indiana and Eastern Illinois are set to hit the hardwood on Saturday, February 21st, 2026. Luckily, we have some clear performance trends emerging now that each team has more than a dozen games under their belts. Use the following data to help analyze this matchup and to place an intelligent wager on its ultimate outcome.

  • SportsBetting3.com Power Rankings - With the 2025-26 season in full stride, Southern Indiana currently has a 94.33 conference power ranking, while the SportsBetting3.com conference power ranking for Eastern Illinois is 96.33.
  • Away Southern Indiana - Southern Indiana starts this game with a 2-9 record as an away team, ranking them 6th in the Ohio Valley Conference for away team wins.
  • Home Eastern Illinois - Eastern Illinois meets Southern Indiana boasting a 9-4 record as a home team. They currently rank 3rd in the Ohio Valley Conference for home team wins.
  • Conference Win Percentage - Southern Indiana currently ranks 6th (0.125) in the Ohio Valley Conference, with Eastern Illinois now standing 4th (0.438) for their conference win percentage in the 2025 Ohio Valley Conference for the 2025-26 college basketball season.
  • Overall Win Percentage - Southern Indiana has a 0.192 overall win percentage, with Eastern Illinois matching up with a 0.407 overall win percentage.
  • Team Records - Southern Indiana currently possesses 5-21 regular season overall record. Meanwhile, Eastern Illinois has tallied a 11-16 standing as the 2025-26 college basketball season continues to unfold.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Moneyline Mage
Moneyline Mage

Prepare for a clash between Southern Indiana (5-21) and Eastern Illinois (11-16).

Conference records are crucial for determining tournament seeds. Southern Indiana is 2-14, while Eastern Illinois is 7-9.

Southern Indiana has lost 6 straight, while Eastern Illinois won their last game. Review the tables below to find the best point spread, total, and moneylines for this game. You can bet on college basketball legally at BetRivers and BetMGM. We've also listed each team's futures odds and current standings below.

Best Screaming Eagles at Panthers Odds


Best Point Spread Betting Odds
Underdog

Southern Indiana
Favorite

Eastern Illinois
Eastern Illinois has a -4.5 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Southern Indiana has a +4.5 -110 point spread at BetMGM OH. Southern Indiana is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 134.5 points. Risk $115 to win $100. BetMGM has the best under line of 134.5 points. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Southern Indiana
Favorite

Eastern Illinois
Eastern Illinois is the -200 moneyline favorite. Risk $200 to win $100 on Eastern Illinois at BetMGM. Southern Indiana is the +165 underdog at BetMGM. Risk $100 to win $165 on Southern Indiana. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Southern Indiana vs Eastern Illinois College Basketball game on Saturday, February 21st, 2026?

Eastern Illinois is a -4.5 -110 point spread favorite at BetMGM, while Southern Indiana is a +4.5 -110 point spread underdog at BetMGM.

What is the over-under total line for the Southern Indiana vs Eastern Illinois College Basketball game on Saturday, February 21st, 2026?

The best over line is 134.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 134.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the moneyline for the Southern Indiana vs Eastern Illinois College Basketball game on Saturday, February 21st, 2026?

Eastern Illinois is a -200 moneyline favorite at BetMGM and Southern Indiana is a +165 moneyline underdog at BetMGM.

College Basketball Odds Example

College Basketball Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Southern Indiana
Eastern Illinois
2/21/26 4:30pm EST
+4.5 -110-4.5 -110
Bet $100 at BetMGM Ohio
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Gambling Problem? Call 1-800-589-9966

Underdog Southern Indiana - Southern Indiana bettors risk $100 to win $90.91 at -110 odds.

A +4.5 Southern Indiana underdog bet wins if they lose by 4 or fewer, tie, or win outright. Your bet loses if they lose by 5 or more.

Favorite Eastern Illinois - Eastern Illinois bettors risk $100 to win $90.91 at -110 odds.

A -4.5 Eastern Illinois favorite bet wins if they win by 5 or more. Your bet loses if they win by 4 or fewer, tie, or lose outright.

Southern Indiana at Eastern Illinois Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Basketball Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Southern Indiana
Eastern Illinois
First to 5 Points
2/21/26 4:30pm EST
+100-140Bet
Southern Indiana
Eastern Illinois
First to 10 Points
2/21/26 4:30pm EST
+105-145Bet
Southern Indiana
Eastern Illinois
First to 15 Points
2/21/26 4:30pm EST
+115-160Bet
Southern Indiana
Eastern Illinois
Game to Overtime
2/21/26 4:30pm EST
Yes +750No -2500Bet

Team Standings

2025-2026 College Basketball Regular Season Standings - Southern Indiana, Eastern Illinois
Team W-L Win% Home Away Conf CGB Conf% Strk
Eastern Illinois13-200.3949-63-138-12+70.400L1
Southern Indiana7-230.2333-104-114-16+110.200L2

Southern Indiana & Eastern Illinois Futures Odds

Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.

Southern Indiana Championship Odds

No NCAA Men's Basketball Tournament TM Southern Indiana YR: futures available

Eastern Illinois Championship Odds

No NCAA Men's Basketball Tournament TM Eastern Illinois YR: futures available

Southern Indiana & Eastern Illinois Team Pages

Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Southern Indiana vs Eastern Illinois College Basketball Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, February 21st, 2026 at 4:30 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Basketball page, look for the Southern Indiana vs Eastern Illinois Game.

    Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the Southern Indiana vs Eastern Illinois Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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