Northern Illinois vs Mississippi State Football Odds

The Huskies will play the Bulldogs on Saturday, September 20th, 2025. The matchup takes place at Davis Wade Stadium. Watch this exciting Week 4 matchup at 4:15 pm EDT. Check local listings for coverage on SEC Network.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

The 2025 college football season continues with Northern Illinois matching up against Mississippi State at Davis Wade Stadium. Let's review how each team is doing so far to better understand how this game will play out.

  • SportsBetting3.com Power Rankings - Northern Illinois has a 98.00 conference power ranking for the 2025 season so far. The 2025 conference power ranking for Mississippi State is 99.33.
  • Away Northern Illinois - Northern Illinois currently has a 0-1 record as an away team for the 2025 regular season, ranking them 2nd in the MAC Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
  • Home Mississippi State - So far, Mississippi State has a 2-0 record as a home team. They currently rank 2nd in the SEC Conference for home team wins in 2025. Keep tabs on this figure, as it will change in the coming weeks.
  • Points Scored - Northern Illinois ranks 10th (28) in the MAC Conference, with Mississippi State currently ranking 7th (121) for points scored in the 2025 SEC Conference.
  • Points Against - Northern Illinois stands 13th (37) in the MAC Conference for points scored by opponents in 2025. Mississippi State sits at 12th (37) in the 2025 SEC Conference for points against in the 2025 season.
  • Team Records - Northern Illinois has a 1-1 regular season overall record, with Mississippi State currently possessing a 3-0 regular season standing for the 2025 NCAAF season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for a wild showdown as Northern Illinois faces off against Mississippi State.

Davis Wade Stadium will be rocking as Mississippi State looks to defend their perfect record.

It's still early in the season, so anything can happen. SportsBetting3.com has you covered - review this game's prop bets and compare the odds below.

Best Huskies at Bulldogs Odds


Best Point Spread Betting Odds
Underdog

Northern Illinois
Favorite

Mississippi State
Mississippi State has a -22.5 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. Northern Illinois has a +22.5 -115 point spread at BetMGM OH. Northern Illinois is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 49.5 points. Risk $110 to win $100. BetMGM has the best under line of 49.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
TBDTBD
Moneyline odds are updating, please check back soon.

Matchup Odds FAQs

What is the point spread for the Northern Illinois vs Mississippi State College Football game on Saturday, September 20th, 2025?

Mississippi State is a -22.5 -105 point spread favorite at BetMGM, while Northern Illinois is a +22.5 -115 point spread underdog at BetMGM.

What is the over-under total line for the Northern Illinois vs Mississippi State College Football game on Saturday, September 20th, 2025?

The best over line is 49.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 49.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Northern Illinois
Mississippi State
9/20/25 4:15pm EDT
+22.5 -115-22.5 -105
Bet $100 at BetMGM Ohio
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Gambling Problem? Call 1-800-589-9966

Underdog Northern Illinois - Northern Illinois bettors risk $100 to win $86.96 at -115 odds.

A +22.5 Northern Illinois underdog bet wins if they lose by 22 or fewer, tie, or win outright. Your bet loses if they lose by 23 or more.

Favorite Mississippi State - Mississippi State bettors risk $100 to win $95.24 at -105 odds.

A -22.5 Mississippi State favorite bet wins if they win by 23 or more. Your bet loses if they win by 22 or fewer, tie, or lose outright.

Northern Illinois at Mississippi State Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Northern Illinois
Mississippi State
9/20/25 4:15pm EDT
Pending BetMGM

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin

Team Standings

2025-2026 College Football Regular Season Standings - Northern Illinois, Mississippi State
Team Conf Conf% W L PF PA Home Away Strk
MAC
Northern Illinois0-00.0001128371-00-1L1
SEC
Mississippi State0-00.00030121372-01-0W3

Northern Illinois & Mississippi State Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Northern Illinois Championship Odds

No NCAA College Football Championship TM Northern Illinois YR: futures available

Mississippi State Championship Odds
2025-26 Mississippi State NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Mississippi State
+100000
Bet

Northern Illinois & Mississippi State Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Northern Illinois Games & Results
WeekMatchupDate & Result
Week 1Holy Cross vs
Northern Illinois
NIU 19, HC 17
Saturday, August 30th, 2025
Week 2Northern Illinois vs
Maryland
MD 20, NIU 9
Friday, September 5th, 2025
Week 4Northern Illinois vs
Mississippi State
Saturday, September 20th, 2025
4:15 pm EDT
Week 5San Diego State vs
Northern Illinois
Saturday, September 27th, 2025
12:00 am EDT
Week 6Miami (OH) vs
Northern Illinois
Saturday, October 4th, 2025
12:00 am EDT
Week 7Northern Illinois vs
Eastern Michigan
Saturday, October 11th, 2025
12:00 am EDT
Week 8Northern Illinois vs
Ohio
Saturday, October 18th, 2025
12:00 am EDT
Week 9Ball State vs
Northern Illinois
Saturday, October 25th, 2025
12:00 am EDT
Week 11Northern Illinois vs
Toledo
Wednesday, November 5th, 2025
12:00 am EST
Week 12Northern Illinois vs
UMass
Wednesday, November 12th, 2025
7:00 pm EST
Week 13Western Michigan vs
Northern Illinois
Tuesday, November 18th, 2025
7:00 pm EST
Week 14Kent State vs
Northern Illinois
Friday, November 28th, 2025
12:00 pm EST


2025-26 Mississippi State Games & Results
WeekMatchupDate & Result
Week 1Mississippi State vs
Southern Miss
MSST 34, USM 17
Saturday, August 30th, 2025
Week 2Arizona State vs
Mississippi State
MSST 24, ASU 20
Saturday, September 6th, 2025
Week 3Alcorn State vs
Mississippi State
MSST 63, ALCN 0
Saturday, September 13th, 2025
Week 4Northern Illinois vs
Mississippi State
Saturday, September 20th, 2025
4:15 pm EDT
Week 5Tennessee vs
Mississippi State
Saturday, September 27th, 2025
12:00 am EDT
Week 6Mississippi State vs
Texas A&M
Saturday, October 4th, 2025
12:00 am EDT
Week 8Mississippi State vs
Florida
Saturday, October 18th, 2025
12:00 am EDT
Week 9Texas vs
Mississippi State
Saturday, October 25th, 2025
12:00 am EDT
Week 10Mississippi State vs
Arkansas
Saturday, November 1st, 2025
12:00 am EDT
Week 11Georgia vs
Mississippi State
Saturday, November 8th, 2025
12:00 pm EST
Week 12Mississippi State vs
Missouri
Saturday, November 15th, 2025
12:00 am EST
Week 14Ole Miss vs
Mississippi State
Friday, November 28th, 2025
12:00 pm EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Northern Illinois vs Mississippi State College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 20th, 2025 at 4:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Northern Illinois vs Mississippi State Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Northern Illinois vs Mississippi State Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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