Purdue vs Notre Dame Football Odds

The Boilermakers will play the Fighting Irish on Saturday, September 20th, 2025. The matchup takes place at Notre Dame Stadium. Watch this exciting Week 4 matchup at 3:30 pm EDT. Check local listings for coverage on NBC, Peacock.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

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Matchup Stats
Paddy O'Parlay
Best Odds
Interactive Odds Example
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Recent Meetings
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Key Matchup Stats

The 2025 college football season continues with Purdue matching up against Notre Dame at Notre Dame Stadium. Let's review how each team is doing so far to better understand how this game will play out.

SportsBetting3.com Power Rankings - Purdue has a 94.33 conference power ranking for the 2025 season so far. The 2025 conference power ranking for Notre Dame is 98.00.
Away Purdue - Purdue currently has a 0-0 record as an away team for the 2025 regular season, ranking them 2nd in the Big Ten Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
Home Notre Dame - So far, Notre Dame has a 0-1 record as a home team. They currently rank 2nd in the Independent Conference for home team wins in 2025. Keep tabs on this figure, as it will change in the coming weeks.
Points Scored - Purdue ranks 14th (82) in the Big Ten Conference, with Notre Dame currently ranking 2nd (64) for points scored in the 2025 Independent Conference.
Points Against - Purdue stands 5th (50) in the Big Ten Conference for points scored by opponents in 2025. Notre Dame sits at 2nd (68) in the 2025 Independent Conference for points against in the 2025 season.
Team Records - Purdue has a 2-1 regular season overall record, with Notre Dame currently possessing a 0-2 regular season standing for the 2025 NCAAF season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Get ready for a wild showdown at Notre Dame Stadium as Purdue faces off against Notre Dame.

Notre Dame is hungry for a win after starting the season 0-2, while Purdue sits at 2-1.

This early matchup will set the tone for both teams moving forward. Don't miss out! Visit SportsBetting3.com to review this game's prop bets and compare the odds below.

Best Boilermakers at Fighting Irish Odds

**Best Point Spread Betting Odds**
Underdog Purdue	Favorite Notre Dame
+24.5 -105 BetMGM Bet	-24.5 -115 BetMGM Bet

Notre Dame has a -24.5 -115 point spread at BetMGM OH. They are the point spread favorite in this matchup. Purdue has a +24.5 -105 point spread at BetMGM OH. Purdue is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

**Best Total Betting Odds**
Over	Under
51.5 o -105 BetMGM Bet	51.5 u -115 BetMGM Bet

BetMGM has the best over line of 51.5 points. Risk $105 to win $100. BetMGM has the best under line of 51.5 points. Risk $115 to win $100. Our tutorial explains more about total bets.

**Best Moneyline Betting Odds**
Underdog Purdue	Favorite Notre Dame
+1400 BetMGM Bet	-5000 BetMGM Bet

Notre Dame is the -5000 moneyline favorite. Risk $5,000 to win $100 on Notre Dame at BetMGM. Purdue is the +1400 underdog at BetMGM. Risk $100 to win $1,400 on Purdue. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Purdue vs Notre Dame College Football game on Saturday, September 20th, 2025?

Notre Dame is a -24.5 -115 point spread favorite at BetMGM, while Purdue is a +24.5 -105 point spread underdog at BetMGM.

What is the over-under total line for the Purdue vs Notre Dame College Football game on Saturday, September 20th, 2025?

The best over line is 51.5 -105 points at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 51.5 -115 points at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the moneyline for the Purdue vs Notre Dame College Football game on Saturday, September 20th, 2025?

Notre Dame is a -5000 moneyline favorite at BetMGM and Purdue is a +1400 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained
Game	BetMGM Bet
Purdue Notre Dame 9/20/25 3:30pm EDT	+24.5 -105 -24.5 -115

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Underdog Purdue - Purdue bettors risk $100 to win $95.24 at -105 odds.

A +24.5 Purdue underdog bet wins if they lose by 24 or fewer, tie, or win outright. Your bet loses if they lose by 25 or more.

Favorite Notre Dame - Notre Dame bettors risk $100 to win $86.96 at -115 odds.

A -24.5 Notre Dame favorite bet wins if they win by 25 or more. Your bet loses if they win by 24 or fewer, tie, or lose outright.

Purdue at Notre Dame Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
	BetMGM Bet
Purdue Notre Dame 9/20/25 3:30pm EDT	Pending BetMGM

Recent Meetings Since 2021

Recent Meetings Since 2021
Week	Game	Result	Margin
2025 Week 4	Purdue vs Notre Dame Saturday, September 20th, 2025	ND 56, PUR 30 Notre Dame Stadium	Notre Dame by 26
2024 Week 3	Notre Dame vs Purdue Saturday, September 14th, 2024	ND 66, PUR 7 Ross-Ade Stadium	Notre Dame by 59
2021 Week 3	Purdue vs Notre Dame Saturday, September 18th, 2021	ND 27, PUR 13 Notre Dame Stadium	Notre Dame by 14

Team Standings

2025-2026 College Football Regular Season Standings - Purdue, Notre Dame
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
Independent
#16 Notre Dame	0-0	0.000	4	2	240	125	3-1	1-1	W4
Big Ten
Purdue	0-3	0.000	2	4	159	176	2-2	0-2	L4

Purdue & Notre Dame Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Purdue Championship Odds

2025-26 Purdue NCAA College Football Championship Odds
Team	BetMGM
Purdue	+100000 Bet

Notre Dame Championship Odds

2025-26 Notre Dame NCAA College Football Championship Odds
Team	BetMGM
Notre Dame	+1700 Bet

Purdue & Notre Dame Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2025-26 Purdue Games & Results
Week	Matchup	Date & Result
Week 1	Ball State vs Purdue	PUR 31, BALL 0 Saturday, August 30th, 2025
Week 2	Southern Illinois vs Purdue	PUR 34, SIU 17 Saturday, September 6th, 2025
Week 3	USC vs Purdue	USC 33, PUR 17 Saturday, September 13th, 2025
Week 4	Purdue vs Notre Dame	ND 56, PUR 30 Saturday, September 20th, 2025
Week 6	Illinois vs Purdue	ILL 43, PUR 27 Saturday, October 4th, 2025
Week 7	Purdue vs Minnesota	MINN 27, PUR 20 Saturday, October 11th, 2025
Week 8	Purdue vs Northwestern	Saturday, October 18th, 2025 3:00 pm EDT
Week 9	Rutgers vs Purdue	Saturday, October 25th, 2025 12:00 am EDT
Week 10	Purdue vs Michigan	Saturday, November 1st, 2025 12:00 am EDT
Week 11	Ohio State vs Purdue	Saturday, November 8th, 2025 12:00 am EST
Week 12	Purdue vs Washington	Saturday, November 15th, 2025 12:00 am EST
Week 14	Indiana vs Purdue	Friday, November 28th, 2025 7:30 pm EST

2025-26 Notre Dame Games & Results
Week	Matchup	Date & Result
Week 1	Notre Dame vs Miami (FL)	MIA 27, ND 24 Sunday, August 31st, 2025
Week 3	Texas A&M vs Notre Dame	TA&M 41, ND 40 Saturday, September 13th, 2025
Week 4	Purdue vs Notre Dame	ND 56, PUR 30 Saturday, September 20th, 2025
Week 5	Notre Dame vs Arkansas	ND 56, ARK 13 Saturday, September 27th, 2025
Week 6	Boise State vs Notre Dame	ND 28, BOIS 7 Saturday, October 4th, 2025
Week 7	NC State vs Notre Dame	ND 36, NCSU 7 Saturday, October 11th, 2025
Week 8	USC vs Notre Dame	Saturday, October 18th, 2025 7:30 pm EDT
Week 10	Notre Dame vs Boston College	Saturday, November 1st, 2025 12:00 am EDT
Week 11	Navy vs Notre Dame	Saturday, November 8th, 2025 7:30 pm EST
Week 12	Notre Dame vs Pittsburgh	Saturday, November 15th, 2025 12:00 am EST
Week 13	Syracuse vs Notre Dame	Saturday, November 22nd, 2025 3:30 pm EST
Week 14	Notre Dame vs Stanford	Saturday, November 29th, 2025 12:00 am EST

How to Bet on the Game

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How to Bet on the Purdue vs Notre Dame College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 20th, 2025 at 3:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the Purdue vs Notre Dame Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Purdue vs Notre Dame Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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