Syracuse vs Clemson Football Odds

The Orange will play the Tigers on Saturday, October 22nd, 2022. The matchup takes place at Memorial Stadium (Clemson, SC). Watch this exciting Week 8 matchup at 12:00 pm EDT. Check local listings for coverage on ABC.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

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Best Orange at Tigers Odds

**Best Point Spread Betting Odds**
Underdog Syracuse	Favorite Clemson
+14 -110 BetMGM Bet	-14 -110 BetMGM Bet
+14 -110 BetRivers	-14 -110 BetRivers

Clemson has a -14 -110 point spread at BetMGM PA. They are the point spread favorite in this matchup. Syracuse has a +14 -110 point spread at BetMGM PA. Syracuse is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

**Best Total Betting Odds**
Over	Under
49.5 o -112 BetRivers Bet	50 u -110 BetMGM Bet
50 o -110 BetMGM	49.5 u -109 BetRivers

BetRivers has the best over line of 49.5 points. Risk $112 to win $100. BetMGM has the best under line of 50 points. Risk $110 to win $100. Our tutorial explains more about total bets.

**Best Moneyline Betting Odds**
Underdog Syracuse	Favorite Clemson
+430 BetRivers Bet	-600 BetMGM Bet
+425 BetMGM	-670 BetRivers

Clemson is the -600 moneyline favorite. Risk $600 to win $100 on Clemson at BetMGM. Syracuse is the +430 underdog at BetRivers. Risk $100 to win $430 on Syracuse. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Syracuse vs Clemson College Football game on Saturday, October 22nd, 2022?

Clemson is a -14 -110 point spread favorite at BetMGM, while Syracuse is a +14 -110 point spread underdog at BetMGM.

What is the over-under total line for the Syracuse vs Clemson College Football game on Saturday, October 22nd, 2022?

The best over line is 49.5 -112 points at BetRivers, which means you risk $112 to win $100 betting the over. The best under line is 50 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Syracuse vs Clemson College Football game on Saturday, October 22nd, 2022?

Clemson is a -600 moneyline favorite at BetMGM and Syracuse is a +430 moneyline underdog at BetRivers.

College Football Odds Example

College Football Odds and Outcomes Explained
Game	BetMGM Bet
Syracuse Clemson 10/22/22 12:00pm EDT	+14 -110 -14 -110

Bet $100 at BetMGM Pennsylvania
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Underdog Syracuse - Syracuse bettors risk $100 to win $90.91 at -110 odds.

A +14 Syracuse underdog bet wins if they lose by 13 or fewer, tie, or win outright. The bet pushes if they lose by 14. Your bet loses if they lose by 15 or more.

Favorite Clemson - Clemson bettors risk $100 to win $90.91 at -110 odds.

A -14 Clemson favorite bet wins if they win by 15 or more. The bet pushes if they win by 14. Your bet loses if they win by 13 or fewer, tie, or lose outright.

Syracuse at Clemson Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
	BetMGM Bet
Syracuse Clemson 10/22/22 12:00pm EDT	Pending BetMGM

Recent Meetings Since 2018

Recent Meetings Since 2018
Week	Game	Result	Margin
2023 Week 5	Clemson vs Syracuse Saturday, September 30th, 2023	CLEM 31, SYR 14 JMA Wireless Dome	Clemson by 17
2022 Week 8	Syracuse vs Clemson Saturday, October 22nd, 2022	CLEM 27, SYR 21 Memorial Stadium (Clemson, SC)	Clemson by 6
2021 Week 7	Clemson vs Syracuse Friday, October 15th, 2021	CLEM 17, SYR 14 JMA Wireless Dome	Clemson by 3
2020 Week 8	Syracuse vs Clemson Saturday, October 24th, 2020	CLEM 47, SYR 21 Memorial Stadium (Clemson, SC)	Clemson by 26
2019 Week 3	Clemson vs Syracuse Saturday, September 14th, 2019	CLEM 41, SYR 6 JMA Wireless Dome	Clemson by 35
2018 Week 5	Syracuse vs Clemson Saturday, September 29th, 2018	CLEM 27, SYR 23 Memorial Stadium (Clemson, SC)	Clemson by 4

Team Standings

2022-2023 College Football Regular Season Standings - Syracuse, Clemson
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
#13 Clemson	8-0	1.000	11	3	465	292	6-1	4-1	L1
Syracuse	4-4	0.500	7	6	360	300	5-2	2-3	L1

Syracuse & Clemson Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Syracuse Championship Odds

2025-26 Syracuse NCAA College Football Championship Odds
Team	BetRivers
Syracuse	+20000 Bet

Clemson Championship Odds

2025-26 Clemson NCAA College Football Championship Odds
Team	BetRivers
Clemson	+1600 Bet

Syracuse & Clemson Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2022-23 Syracuse Games & Results
Week	Matchup	Date & Result
Week 1	Louisville vs Syracuse	SYR 31, LOU 7 Saturday, September 3rd, 2022
Week 2	Syracuse vs UConn	SYR 48, CONN 14 Saturday, September 10th, 2022
Week 3	Purdue vs Syracuse	SYR 32, PUR 29 Saturday, September 17th, 2022
Week 4	Virginia vs Syracuse	SYR 22, UVA 20 Friday, September 23rd, 2022
Week 5	Wagner vs Syracuse	SYR 59, WAG 0 Saturday, October 1st, 2022
Week 7	NC State vs Syracuse	SYR 24, NCST 9 Saturday, October 15th, 2022
Week 8	Syracuse vs Clemson	CLEM 27, SYR 21 Saturday, October 22nd, 2022
Week 9	Notre Dame vs Syracuse	ND 41, SYR 24 Saturday, October 29th, 2022
Week 10	Syracuse vs Pittsburgh	PITT 19, SYR 9 Saturday, November 5th, 2022
Week 11	Florida State vs Syracuse	FSU 38, SYR 3 Saturday, November 12th, 2022
Week 12	Syracuse vs Wake Forest	WAKE 45, SYR 35 Saturday, November 19th, 2022
Week 13	Syracuse vs Boston College	SYR 32, BC 23 Saturday, November 26th, 2022
Bowls	Syracuse vs Minnesota Bad Boy Mowers Pinstripe Bowl	MINN 28, SYR 20 Thursday, December 29th, 2022

2022-23 Clemson Games & Results
Week	Matchup	Date & Result
Week 1	Clemson vs Georgia Tech	CLEM 41, GT 10 Monday, September 5th, 2022
Week 2	Furman vs Clemson	CLEM 35, FUR 12 Saturday, September 10th, 2022
Week 3	Louisiana Tech vs Clemson	CLEM 48, LT 20 Saturday, September 17th, 2022
Week 4	Clemson vs Wake Forest	CLEM 51, WAKE 45 (2OT) Saturday, September 24th, 2022
Week 5	NC State vs Clemson	CLEM 30, NCST 20 Saturday, October 1st, 2022
Week 6	Clemson vs Boston College	CLEM 31, BC 3 Saturday, October 8th, 2022
Week 7	Clemson vs Florida State	CLEM 34, FSU 28 Saturday, October 15th, 2022
Week 8	Syracuse vs Clemson	CLEM 27, SYR 21 Saturday, October 22nd, 2022
Week 10	Clemson vs Notre Dame	ND 35, CLEM 14 Saturday, November 5th, 2022
Week 11	Louisville vs Clemson	CLEM 31, LOU 16 Saturday, November 12th, 2022
Week 12	Miami (FL) vs Clemson	CLEM 40, MIA 10 Saturday, November 19th, 2022
Week 13	South Carolina vs Clemson	SC 31, CLEM 30 Saturday, November 26th, 2022
Week 14	Clemson vs North Carolina	CLEM 39, UNC 10 Saturday, December 3rd, 2022
Bowls	Tennessee vs Clemson Capital One Orange Bowl	TENN 31, CLEM 14 Friday, December 30th, 2022

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Syracuse vs Clemson College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, October 22nd, 2022 at 12:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the Syracuse vs Clemson Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Syracuse vs Clemson Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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