Wyoming vs Colorado Football Odds

The Cowboys will play the Buffaloes on Saturday, September 20th, 2025. The matchup takes place at Folsom Field. Watch this exciting Week 4 matchup at 10:15 pm EDT. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

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Matchup Stats
Paddy O'Parlay
Best Odds
Interactive Odds Example
Prop Bets
Recent Meetings
Team Standings
Futures Odds
Team Pages
Team Schedules & Results
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Key Matchup Stats

We're now well into the 2025 college football season. Week 4 action features a matchup between Wyoming and Colorado taking place at Folsom Field. The following are some key season stats to help you size up this game.

SportsBetting3.com Power Rankings - Wyoming has a 96.33 conference power ranking for the 2025 season. The conference power ranking for Colorado is 92.67.
Away Wyoming - Heading into Week 4, Wyoming currently has a 1-0 record as an away team for the 2025 regular season. This ranks them 1st in the Mountain West Conference for away team wins. Watch this stat carefully as the season progresses.
Home Colorado - Colorado has a 1-1 record as a home team. Looking ahead to this 2025 Week 4 matchup, they rank 3rd in the Big 12 Conference for home team wins. Like the Wyoming away record and ranking, you should continually keep tabs on this stat.
Points Scored - For the 2025 season, Wyoming ranks 9th (47) in the Mountain West Conference, with Colorado currently ranking 15th (71) for points scored in the Big 12 Conference.
Points Against - Also in 2025, Wyoming stands 11th (38) in the Mountain West Conference for points scored by opponents in 2025. Colorado sits at 4th (70) in the Big 12 Conference for points against in the 2025 season so far.
Team Records - Wyoming has a 2-1 overall record for the 2025 regular season, with Colorado currently 1-2 for the 2025 NCAAF regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Get ready for a wild showdown as Wyoming battles Colorado in a Week 4 matchup!

The game will be held at Folsom Field, creating an electric atmosphere for fans.

Wyoming holds a higher Power Ranking of 96.33 compared to Colorado's 92.67.

Wyoming sits at 2-1 while Colorado is at 1-2. Bet this game at BetRivers or BetMGM, review this game's prop bets, and compare the odds below!

Best Cowboys at Buffaloes Odds

**Best Point Spread Betting Odds**
Underdog Wyoming	Favorite Colorado
+11.5 -110 BetMGM Bet	-11.5 -110 BetMGM Bet

Colorado has a -11.5 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Wyoming has a +11.5 -110 point spread at BetMGM OH. Wyoming is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

**Best Total Betting Odds**
Over	Under
45.5 o -110 BetMGM Bet	45.5 u -110 BetMGM Bet

BetMGM has the best over line of 45.5 points. Risk $110 to win $100. BetMGM has the best under line of 45.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

**Best Moneyline Betting Odds**
Underdog Wyoming	Favorite Colorado
+375 BetMGM Bet	-500 BetMGM Bet

Colorado is the -500 moneyline favorite. Risk $500 to win $100 on Colorado at BetMGM. Wyoming is the +375 underdog at BetMGM. Risk $100 to win $375 on Wyoming. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Wyoming vs Colorado College Football game on Saturday, September 20th, 2025?

Colorado is a -11.5 -110 point spread favorite at BetMGM, while Wyoming is a +11.5 -110 point spread underdog at BetMGM.

What is the over-under total line for the Wyoming vs Colorado College Football game on Saturday, September 20th, 2025?

The best over line is 45.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 45.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Wyoming vs Colorado College Football game on Saturday, September 20th, 2025?

Colorado is a -500 moneyline favorite at BetMGM and Wyoming is a +375 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained
Game	BetMGM Bet
Wyoming Colorado 9/20/25 10:15pm EDT	+11.5 -110 -11.5 -110

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Underdog Wyoming - Wyoming bettors risk $100 to win $90.91 at -110 odds.

A +11.5 Wyoming underdog bet wins if they lose by 11 or fewer, tie, or win outright. Your bet loses if they lose by 12 or more.

Favorite Colorado - Colorado bettors risk $100 to win $90.91 at -110 odds.

A -11.5 Colorado favorite bet wins if they win by 12 or more. Your bet loses if they win by 11 or fewer, tie, or lose outright.

Wyoming at Colorado Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
	BetMGM Bet
Wyoming Colorado No Touchdown To Score 1st Touchdown 9/20/25 10:15pm EDT	+185 -285 +10000 Bet
Wyoming Colorado Game to Overtime 9/20/25 10:15pm EDT	Yes +1350 No -10000 Bet
Wyoming Colorado Both Teams Score 10+ 9/20/25 10:15pm EDT	Yes -375 No +270 Bet
Wyoming Colorado Both Teams Score 20+ 9/20/25 10:15pm EDT	Yes +175 No -225 Bet
	BetMGM
Wyoming Colorado Both Teams Score 30+ 9/20/25 10:15pm EDT	Yes +1000 No -3000 Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
Week	Game	Result	Margin
2025 Week 4	Wyoming vs Colorado Saturday, September 20th, 2025	COLO 37, WYO 20 Folsom Field	Colorado by 17

Team Standings

2025-2026 College Football Regular Season Standings - Wyoming, Colorado
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
Big 12
Colorado	1-4	0.200	3	5	181	219	3-2	0-3	L1
Mountain West
Wyoming	2-2	0.500	4	4	168	158	3-2	1-2	W1

Wyoming & Colorado Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Wyoming Championship Odds

No NCAA College Football Championship TM Wyoming YR: futures available

Colorado Championship Odds

No NCAA College Football Championship TM Colorado YR: futures available

Wyoming & Colorado Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2025-26 Wyoming Games & Results
Week	Matchup	Date & Result
Week 1	Wyoming vs Akron	WYO 10, AKR 0 Thursday, August 28th, 2025
Week 1	Wyoming vs Akron	Saturday, August 30th, 2025 12:00 am EDT
Week 2	Northern Iowa vs Wyoming	WYO 31, UNI 7 Saturday, September 6th, 2025
Week 3	Utah vs Wyoming	UTAH 31, WYO 6 Saturday, September 13th, 2025
Week 4	Wyoming vs Colorado	COLO 37, WYO 20 Saturday, September 20th, 2025
Week 6	UNLV vs Wyoming	UNLV 31, WYO 17 Saturday, October 4th, 2025
Week 7	San Jose State vs Wyoming	WYO 35, SJSU 28 Saturday, October 11th, 2025
Week 8	Wyoming vs Air Force	AFA 24, WYO 21 Saturday, October 18th, 2025
Week 9	Colorado State vs Wyoming	Saturday, October 25th, 2025 7:30 pm EDT
Week 10	Wyoming vs San Diego State	Saturday, November 1st, 2025 7:00 pm EDT
Week 12	Wyoming vs Fresno State	Saturday, November 15th, 2025 12:00 am EST
Week 13	Nevada vs Wyoming	Saturday, November 22nd, 2025 2:00 pm EST
Week 14	Wyoming vs Hawaii	Saturday, November 29th, 2025 11:00 pm EST

2025-26 Colorado Games & Results
Week	Matchup	Date & Result
Week 1	Georgia Tech vs Colorado	GT 27, COLO 20 Friday, August 29th, 2025
Week 2	Delaware vs Colorado	COLO 31, DEL 7 Saturday, September 6th, 2025
Week 3	Colorado vs Houston	HOU 36, COLO 20 Friday, September 12th, 2025
Week 4	Wyoming vs Colorado	COLO 37, WYO 20 Saturday, September 20th, 2025
Week 5	BYU vs Colorado	BYU 24, COLO 21 Saturday, September 27th, 2025
Week 6	Colorado vs TCU	TCU 35, COLO 21 Saturday, October 4th, 2025
Week 7	Iowa State vs Colorado	COLO 24, ISU 17 Saturday, October 11th, 2025
Week 9	Colorado vs Utah	Saturday, October 25th, 2025 10:15 pm EDT
Week 10	Arizona vs Colorado	Saturday, November 1st, 2025 12:00 am EDT
Week 11	Colorado vs West Virginia	Saturday, November 8th, 2025 12:00 am EST
Week 13	Arizona State vs Colorado	Saturday, November 22nd, 2025 12:00 am EST
Week 14	Colorado vs Kansas State	Saturday, November 29th, 2025 12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Wyoming vs Colorado College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 20th, 2025 at 10:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the Wyoming vs Colorado Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Wyoming vs Colorado Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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