The Tigers will play the Fighting Irish on Saturday, November 5th, 2022. The matchup takes place at Notre Dame Stadium. Watch this exciting Week 10 matchup at 7:40 pm EDT. Check local listings for coverage on NBC, Peacock.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Schedules & Results
- Other Games Today
Best Tigers at Fighting Irish Odds
| Underdog Notre Dame | Favorite Clemson |
|---|---|
| Over | Under |
|---|---|
| Underdog Notre Dame | Favorite Clemson |
|---|---|
Matchup Odds FAQs
Clemson is a -3.5 -115 point spread favorite at BetRivers, while Notre Dame is a +3.5 -105 point spread underdog at BetMGM.
The best over line is 43.5 -110 points at BetRivers, which means you risk $110 to win $100 betting the over. The best under line is 43.5 -110 points at BetRivers, and that means you risk $110 to win $100 betting the under.
Clemson is a -167 moneyline favorite at BetRivers and Notre Dame is a +145 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetRiversBet |
|---|---|
Clemson
Notre Dame
11/05/22 7:40pm EDT |
Underdog Notre Dame - Notre Dame bettors risk $100 to win $94.34 at -106 odds.
A +3.5 Notre Dame underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.
Favorite Clemson - Clemson bettors risk $100 to win $86.96 at -115 odds.
A -3.5 Clemson favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.
Clemson at Notre Dame Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetRivers Bet |
|
|---|---|
Clemson
Notre Dame
First Team To Score
11/05/22 7:40pm EDT | Bet |
Clemson
Notre Dame
Tie
First to 15 Points
11/05/22 7:40pm EDT | Bet |
Clemson
Notre Dame
Tie
First to 20 Points
11/05/22 7:40pm EDT | Bet |
Recent Meetings Since 2018
| Week | Game | Result | Margin |
|---|---|---|---|
| 2022 Week 10 | Clemson vs Notre Dame Saturday, November 5th, 2022 | ND 35, CLEM 14 Notre Dame Stadium | Notre Dame by 21 |
| 2020 Week 16 | Clemson vs Notre Dame Saturday, December 19th, 2020 | CLEM 34, ND 10 Bank of America Stadium | Clemson by 24 |
| 2020 Week 10 | Clemson vs Notre Dame Saturday, November 7th, 2020 | ND 47, CLEM 40 (2OT) Notre Dame Stadium | Notre Dame by 7 |
| 2018 Bowls | Notre Dame vs Clemson Saturday, December 29th, 2018 Goodyear Cotton Bowl Classic - CFP Semifinal | CLEM 30, ND 3 AT&T Stadium | Clemson by 27 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| ACC Atlantic | |||||||||
| #13 Clemson | 8-0 | 1.000 | 11 | 3 | 465 | 292 | 6-1 | 4-1 | L1 |
| Independent | |||||||||
| #18 Notre Dame | 0-0 | 0.000 | 9 | 4 | 413 | 299 | 4-2 | 2-2 | W1 |
Clemson & Notre Dame Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.
Clemson Championship Odds|
Team | BetRivers |
 BetMGM |
|---|---|---|
| Clemson |
|
Team | BetRivers |
BetMGM |
|---|---|---|
| Notre Dame |
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Clemson vs Georgia Tech | CLEM 41, GT 10 Monday, September 5th, 2022 |
| Week 2 | Furman vs Clemson | CLEM 35, FUR 12 Saturday, September 10th, 2022 |
| Week 3 | Louisiana Tech vs Clemson | CLEM 48, LT 20 Saturday, September 17th, 2022 |
| Week 4 | Clemson vs Wake Forest | CLEM 51, WAKE 45 (2OT) Saturday, September 24th, 2022 |
| Week 5 | NC State vs Clemson | CLEM 30, NCST 20 Saturday, October 1st, 2022 |
| Week 6 | Clemson vs Boston College | CLEM 31, BC 3 Saturday, October 8th, 2022 |
| Week 7 | Clemson vs Florida State | CLEM 34, FSU 28 Saturday, October 15th, 2022 |
| Week 8 | Syracuse vs Clemson | CLEM 27, SYR 21 Saturday, October 22nd, 2022 |
| Week 10 | Clemson vs Notre Dame | ND 35, CLEM 14 Saturday, November 5th, 2022 |
| Week 11 | Louisville vs Clemson | CLEM 31, LOU 16 Saturday, November 12th, 2022 |
| Week 12 | Miami (FL) vs Clemson | CLEM 40, MIA 10 Saturday, November 19th, 2022 |
| Week 13 | South Carolina vs Clemson | SC 31, CLEM 30 Saturday, November 26th, 2022 |
| Week 14 | Clemson vs North Carolina | CLEM 39, UNC 10 Saturday, December 3rd, 2022 |
| Bowls | Tennessee vs Clemson Capital One Orange Bowl | TENN 31, CLEM 14 Friday, December 30th, 2022 |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Notre Dame vs Ohio State | OSU 21, ND 10 Saturday, September 3rd, 2022 |
| Week 2 | Marshall vs Notre Dame | MRSH 26, ND 21 Saturday, September 10th, 2022 |
| Week 3 | California vs Notre Dame | ND 24, CAL 17 Saturday, September 17th, 2022 |
| Week 4 | Notre Dame vs North Carolina | ND 45, UNC 32 Saturday, September 24th, 2022 |
| Week 6 | BYU vs Notre Dame | ND 28, BYU 20 Saturday, October 8th, 2022 |
| Week 7 | Stanford vs Notre Dame | STAN 16, ND 14 Saturday, October 15th, 2022 |
| Week 8 | UNLV vs Notre Dame | ND 44, UNLV 21 Saturday, October 22nd, 2022 |
| Week 9 | Notre Dame vs Syracuse | ND 41, SYR 24 Saturday, October 29th, 2022 |
| Week 10 | Clemson vs Notre Dame | ND 35, CLEM 14 Saturday, November 5th, 2022 |
| Week 11 | Notre Dame vs Navy | ND 35, NAVY 32 Saturday, November 12th, 2022 |
| Week 12 | Boston College vs Notre Dame | ND 44, BC 0 Saturday, November 19th, 2022 |
| Week 13 | Notre Dame vs USC | USC 38, ND 27 Saturday, November 26th, 2022 |
| Bowls | Notre Dame vs South Carolina Taxslayer Gator Bowl | ND 45, SC 38 Friday, December 30th, 2022 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Clemson vs Notre Dame College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 5th, 2022 at 7:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Clemson vs Notre Dame Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Clemson vs Notre Dame Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.