The Spartans will play the Hawkeyes on Saturday, November 22nd, 2025. The matchup takes place at Kinnick Stadium. Watch this exciting Week 13 matchup at 3:30 pm EST. Check local listings for coverage on FS1.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
We're now in the home stretch of the 2025 college football season, with Michigan State and Iowa meeting at Kinnick Stadium for a key late-season matchup on Saturday, November 22nd, 2025. The playoffs are fast approaching, along with the annual Bowl games that kick off in December. Here's an overview of some important 2025 performance data for each team.
- SportsBetting3.com Power Rankings - As we wrap up the 2025 regular season, Michigan State has notched a 89.67 Big Ten Conference conference power ranking. On the other side of the gridiron, Iowa has a 94.33 Big Ten Conference power ranking.
- Away Michigan State - Looking at Week 13, Michigan State heads into this matchup with a 0-4 record as an away team. This ranks them 5th in the Big Ten Conference for away team wins in 2025. Remember that a team's overall record and schedule strength will affect whether or not they make a December bowl game or qualify for the playoffs.
- Home Iowa - Meanwhile, Iowa has a 4-2 record as a home team for 2025. They currently rank 4th in the Big Ten Conference for home team wins. Let's see if they can add another win to their record when they battle Michigan State on Saturday, November 22nd, 2025.
- Points Scored - Now late in the 2025 season, Michigan State ranks 12th (240) in the Big Ten Conference, with Iowa currently ranking 10th (287) for points scored in the Big Ten Conference.
- Points Against - Michigan State currently stands 3rd (311) in the Big Ten Conference for points scored by opponents in the 2025 college football season. Their opponent, Iowa, ranks 15th (149) in the Big Ten Conference for points against them as the 2025 college football season comes to a close.
- Team Records - As we head into Week 13, Michigan State has a 3-7 overall record for the 2025 regular season, with Iowa possessing a 6-4 standing for the 2025 college football season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Top o' the morning to ya, lads and lasses! Michigan State faces Iowa in a clash!
This Week 13 showdown takes place at Kinnick Stadium, where the Hawkeyes host the Spartans.
With the regular season winding down, bowl games are on the horizon. Who will prevail?
According to SportsBetting3.com Power Rankings, Iowa holds the edge over Michigan State.
The Spartans have a 3-7 record, while the Hawkeyes boast a 6-4 standing.
We recommend BetRivers or BetMGM for a bet on this game. Review this game's prop bets.
Compare the best point spread, total, and moneylines from our partner sportsbooks below.
Best Spartans at Hawkeyes Odds
| Underdog Michigan State | Favorite Iowa |
|---|---|
| Over | Under |
|---|---|
| Underdog Michigan State | Favorite Iowa |
|---|---|
Matchup Odds FAQs
Iowa is a -17 -110 point spread favorite at BetMGM, while Michigan State is a +17 -110 point spread underdog at BetMGM.
The best over line is 42.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 42.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
Iowa is a -900 moneyline favorite at BetMGM and Michigan State is a +600 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
Michigan State
Iowa
11/22/25 3:30pm EST | +17 -110-17 -110 |
Underdog Michigan State - Michigan State bettors risk $100 to win $90.91 at -110 odds.
A +17 Michigan State underdog bet wins if they lose by 16 or fewer, tie, or win outright. The bet pushes if they lose by 17. Your bet loses if they lose by 18 or more.
Favorite Iowa - Iowa bettors risk $100 to win $90.91 at -110 odds.
A -17 Iowa favorite bet wins if they win by 18 or more. The bet pushes if they win by 17. Your bet loses if they win by 16 or fewer, tie, or lose outright.
Michigan State at Iowa Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Michigan State
Iowa
No Touchdown
To Score 1st Touchdown
11/22/25 3:30pm EST | +275-450+10000Bet |
Michigan State
Iowa
Game to Overtime
11/22/25 3:30pm EST | Yes +1800No -10000Bet |
Michigan State
Iowa
Both Teams Score 10+
11/22/25 3:30pm EST | Yes -200No +154Bet |
Michigan State
Iowa
Both Teams Score 20+
11/22/25 3:30pm EST | Yes +340No -500Bet |
| BetMGM | |
Michigan State
Iowa
Both Teams Score 30+
11/22/25 3:30pm EST | Yes +2200No -10000Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 13 | Michigan State vs Iowa Saturday, November 22nd, 2025 | IOWA 20, MSU 17 Kinnick Stadium | Iowa by 3 |
| 2024 Week 8 | Iowa vs Michigan State Saturday, October 19th, 2024 | MSU 32, IOWA 20 Spartan Stadium | Michigan State by 12 |
| 2023 Week 5 | Michigan State vs Iowa Saturday, September 30th, 2023 | IOWA 26, MSU 16 Kinnick Stadium | Iowa by 10 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| #23 Iowa | 6-3 | 0.667 | 8 | 4 | 347 | 182 | 5-2 | 3-2 | W2 |
| Michigan State | 1-8 | 0.111 | 4 | 8 | 295 | 359 | 3-3 | 0-5 | W1 |
Michigan State & Iowa Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Michigan State Championship OddsNo NCAA College Football Championship TM Michigan State YR: futures available
Iowa Championship OddsNo NCAA College Football Championship TM Iowa YR: futures available
Michigan State & Iowa Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Western Michigan vs Michigan State | MSU 23, WMU 6 Friday, August 29th, 2025 |
| Week 2 | Boston College vs Michigan State | MSU 42, BC 40 (2OT) Saturday, September 6th, 2025 |
| Week 3 | Youngstown State vs Michigan State | MSU 41, YSU 24 Saturday, September 13th, 2025 |
| Week 4 | Michigan State vs USC | USC 45, MSU 31 Saturday, September 20th, 2025 |
| Week 6 | Michigan State vs Nebraska | NEB 38, MSU 27 Saturday, October 4th, 2025 |
| Week 7 | UCLA vs Michigan State | UCLA 38, MSU 13 Saturday, October 11th, 2025 |
| Week 8 | Michigan State vs Indiana | IU 38, MSU 13 Saturday, October 18th, 2025 |
| Week 9 | Michigan vs Michigan State | MICH 31, MSU 20 Saturday, October 25th, 2025 |
| Week 10 | Michigan State vs Minnesota | MINN 23, MSU 20 (OT) Saturday, November 1st, 2025 |
| Week 12 | Penn State vs Michigan State | PSU 28, MSU 10 Saturday, November 15th, 2025 |
| Week 13 | Michigan State vs Iowa | IOWA 20, MSU 17 Saturday, November 22nd, 2025 |
| Week 14 | Maryland vs Michigan State | MSU 38, MD 28 Saturday, November 29th, 2025 |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Albany vs Iowa | IOWA 34, ALB 7 Saturday, August 30th, 2025 |
| Week 2 | Iowa vs Iowa State | ISU 16, IOWA 13 Saturday, September 6th, 2025 |
| Week 3 | UMass vs Iowa | IOWA 47, MASS 7 Saturday, September 13th, 2025 |
| Week 4 | Iowa vs Rutgers | IOWA 38, RUTG 28 Friday, September 19th, 2025 |
| Week 5 | Indiana vs Iowa | IU 20, IOWA 15 Saturday, September 27th, 2025 |
| Week 7 | Iowa vs Wisconsin | IOWA 37, WIS 0 Saturday, October 11th, 2025 |
| Week 8 | Penn State vs Iowa | IOWA 25, PSU 24 Saturday, October 18th, 2025 |
| Week 9 | Minnesota vs Iowa | IOWA 41, MINN 3 Saturday, October 25th, 2025 |
| Week 11 | Oregon vs Iowa | ORE 18, IOWA 16 Saturday, November 8th, 2025 |
| Week 12 | Iowa vs USC | USC 26, IOWA 21 Saturday, November 15th, 2025 |
| Week 13 | Michigan State vs Iowa | IOWA 20, MSU 17 Saturday, November 22nd, 2025 |
| Week 14 | Iowa vs Nebraska | IOWA 40, NEB 16 Friday, November 28th, 2025 |
| Bowls | Iowa vs Vanderbilt Reliaquest Bowl | Wednesday, December 31st, 2025 12:00 pm EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Michigan State vs Iowa College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 22nd, 2025 at 3:30 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Michigan State vs Iowa Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Michigan State vs Iowa Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other November 22, 2025 NCAAFB Games
- Wagner vs Long Island University
- Minnesota vs Northwestern
- Louisville vs SMU
- Harvard vs Yale
- Western Carolina vs VMI
- Bryant vs Stony Brook
- Kansas vs Iowa State
- Miami (FL) vs Virginia Tech
- Delaware vs Wake Forest
- North Carolina Central vs Morgan State
- Missouri vs Oklahoma
- Fordham vs Merrimack College
- Tulsa vs Army
- Rutgers vs Ohio State
- Dartmouth vs Brown
- Albany vs Monmouth
- Lehigh vs Lafayette
- Charlotte vs Georgia
- Baylor vs Arizona
- Washington State vs James Madison
- Old Dominion vs Georgia Southern
- Chattanooga vs Wofford
- Western Illinois vs Gardner-Webb
- Portland State vs Northern Colorado
- Ball State vs Toledo
- Nevada vs Wyoming
- Mercer vs Auburn
- Duquesne vs Robert Morris
- Missouri State vs Kennesaw State
- Eastern Illinois vs Alabama
- Lindenwood vs Southeast Missouri State
- Southern Utah vs North Alabama
- Youngstown State vs Northern Iowa
- Montana State vs Montana
- North Carolina A&T vs Elon
- Tennessee State vs Charleston Southern
- South Dakota State vs North Dakota
- Marshall vs Appalachian State
- Northern Arizona vs Weber State
- Sam Houston State vs Middle Tennessee
- New Mexico State vs UTEP
- Liberty vs Louisiana Tech
- Miss Valley State vs Prairie View A&M
- Incarnate Word vs Houston Christian
- Alabama A&M vs Texas Southern
- UConn vs Florida Atlantic
- South Florida vs UAB
- Norfolk State vs Howard
- Duke vs North Carolina
- Southern Miss vs South Alabama
- Kentucky vs Vanderbilt
- East Carolina vs UTSA
- Jacksonville State vs FIU
- Syracuse vs Notre Dame
- Arkansas vs Texas
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- Michigan vs Maryland
- TCU vs Houston
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- Kansas State vs Utah
- Georgia State vs Troy
- Coastal Carolina vs South Carolina
- Furman vs Clemson
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- BYU vs Cincinnati
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- San Jose State vs San Diego State