Missouri vs Oklahoma Football Odds

The Tigers will play the Sooners on Saturday, November 22nd, 2025. The matchup takes place at Memorial Stadium (Norman, OK). Watch this exciting Week 13 matchup at 12:00 pm EST.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


Bonus
BetMGM Sportsbook#1 BetMGM
REVIEW
New Customers - Up to $1500 Paid Back in Bonus Bets
Bonus Bets Expire in 7 Days
One new customer offer/Add'l Terms

Bet Now
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Table of Contents

Key Matchup Stats

We're now in the home stretch of the 2025 college football season, with Missouri and Oklahoma meeting at Memorial Stadium (Norman, OK) for a key late-season matchup on Saturday, November 22nd, 2025. The playoffs are fast approaching, along with the annual Bowl games that kick off in December. Here's an overview of some important 2025 performance data for each team.

  • SportsBetting3.com Power Rankings - As we wrap up the 2025 regular season, Missouri has notched a 96.33 SEC Conference conference power ranking. On the other side of the gridiron, Oklahoma has a 95.67 SEC Conference power ranking.
  • Away Missouri - Looking at Week 13, Missouri heads into this matchup with a 1-1 record as an away team. This ranks them 4th in the SEC Conference for away team wins in 2025. Remember that a team's overall record and schedule strength will affect whether or not they make a December bowl game or qualify for the playoffs.
  • Home Oklahoma - Meanwhile, Oklahoma has a 4-1 record as a home team for 2025. They currently rank 4th in the SEC Conference for home team wins. Let's see if they can add another win to their record when they battle Missouri on Saturday, November 22nd, 2025.
  • Points Scored - Now late in the 2025 season, Missouri ranks 5th (349) in the SEC Conference, with Oklahoma currently ranking 10th (283) for points scored in the SEC Conference.
  • Points Against - Missouri currently stands 9th (199) in the SEC Conference for points scored by opponents in the 2025 college football season. Their opponent, Oklahoma, ranks 14th (148) in the SEC Conference for points against them as the 2025 college football season comes to a close.
  • Team Records - As we head into Week 13, Missouri has a 7-3 overall record for the 2025 regular season, with Oklahoma possessing a 8-2 standing for the 2025 college football season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for a wild showdown as Missouri faces Oklahoma in a crucial Week 13 matchup.

The game will be held at Memorial Stadium in Norman, OK, on November 22nd.

With the regular season winding down, both teams are vying for a spot in the December bowl games.

Missouri holds a slight edge in the SportsBetting3.com Power Rankings over Oklahoma.

Missouri has a 7-3 standing while Oklahoma comes in with an 8-2 record.

For an exciting wager on this game, we recommend BetRivers or BetMGM.

Don't forget to review this game's prop bets for even more excitement.

Compare the best point spread, total, and moneylines from our partner sportsbooks below.

Best Tigers at Sooners Odds


Best Point Spread Betting Odds
Underdog

Missouri
Favorite

Oklahoma
Oklahoma has a -9.5 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Missouri has a +9.5 -110 point spread at BetMGM OH. Missouri is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 42.5 points. Risk $110 to win $100. BetMGM has the best under line of 42.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Missouri
Favorite

Oklahoma
Oklahoma is the -350 moneyline favorite. Risk $350 to win $100 on Oklahoma at BetMGM. Missouri is the +280 underdog at BetMGM. Risk $100 to win $280 on Missouri. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Missouri vs Oklahoma College Football game on Saturday, November 22nd, 2025?

Oklahoma is a -9.5 -110 point spread favorite at BetMGM, while Missouri is a +9.5 -110 point spread underdog at BetMGM.

What is the over-under total line for the Missouri vs Oklahoma College Football game on Saturday, November 22nd, 2025?

The best over line is 42.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 42.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Missouri vs Oklahoma College Football game on Saturday, November 22nd, 2025?

Oklahoma is a -350 moneyline favorite at BetMGM and Missouri is a +280 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Missouri
Oklahoma
11/22/25 12:00pm EST
+9.5 -110-9.5 -110
Bet $100 at BetMGM Ohio
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Underdog Missouri - Missouri bettors risk $100 to win $90.91 at -110 odds.

A +9.5 Missouri underdog bet wins if they lose by 9 or fewer, tie, or win outright. Your bet loses if they lose by 10 or more.

Favorite Oklahoma - Oklahoma bettors risk $100 to win $90.91 at -110 odds.

A -9.5 Oklahoma favorite bet wins if they win by 10 or more. Your bet loses if they win by 9 or fewer, tie, or lose outright.

Missouri at Oklahoma Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Missouri
Oklahoma
11/22/25 12:00pm EST
Pending BetMGM

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2024
Week 11
Oklahoma vs Missouri
Saturday, November 9th, 2024
MIZ 30, OU 23
Memorial Stadium
Missouri by 7

Team Standings

2025-2026 College Football Regular Season Standings - Missouri, Oklahoma
Team Conf Conf% W L PF PA Home Away Strk
#11 Oklahoma4-20.667822831484-14-0W2
Missouri3-30.500733491996-21-1W1

Missouri & Oklahoma Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Missouri Championship Odds

No NCAA College Football Championship TM Missouri YR: futures available

Oklahoma Championship Odds
2025-26 Oklahoma NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Oklahoma
+2500
Bet

Missouri & Oklahoma Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Missouri Games & Results
WeekMatchupDate & Result
Week 1Central Arkansas vs
Missouri
MIZ 61, CARK 6
Thursday, August 28th, 2025
Week 2Kansas vs
Missouri
MIZ 42, KU 31
Saturday, September 6th, 2025
Week 3Louisiana vs
Missouri
MIZ 52, UL 10
Saturday, September 13th, 2025
Week 4South Carolina vs
Missouri
MIZ 29, SC 20
Saturday, September 20th, 2025
Week 5UMass vs
Missouri
MIZ 42, MASS 6
Saturday, September 27th, 2025
Week 7Alabama vs
Missouri
ALA 27, MIZ 24
Saturday, October 11th, 2025
Week 8Missouri vs
Auburn
MIZ 23, AUB 17 (2OT)
Saturday, October 18th, 2025
Week 9Missouri vs
Vanderbilt
Saturday, October 25th, 2025
3:30 pm EDT
Week 11Texas A&M vs
Missouri
Saturday, November 8th, 2025
12:00 am EST
Week 12Mississippi State vs
Missouri
Saturday, November 15th, 2025
12:00 am EST
Week 13Missouri vs
Oklahoma
Saturday, November 22nd, 2025
12:00 pm EST
Week 14Missouri vs
Arkansas
Saturday, November 29th, 2025
12:00 am EST


2025-26 Oklahoma Games & Results
WeekMatchupDate & Result
Week 1Illinois State vs
Oklahoma
OU 35, ILST 3
Saturday, August 30th, 2025
Week 2Michigan vs
Oklahoma
OU 24, MICH 13
Saturday, September 6th, 2025
Week 3Oklahoma vs
Temple
OU 42, TEM 3
Saturday, September 13th, 2025
Week 4Auburn vs
Oklahoma
OU 24, AUB 17
Saturday, September 20th, 2025
Week 6Kent State vs
Oklahoma
OU 44, KENT 0
Saturday, October 4th, 2025
Week 7Oklahoma vs
Texas
TEX 23, OU 6
Saturday, October 11th, 2025
Week 8Oklahoma vs
South Carolina
OU 26, SC 7
Saturday, October 18th, 2025
Week 9Ole Miss vs
Oklahoma
Saturday, October 25th, 2025
12:00 pm EDT
Week 10Oklahoma vs
Tennessee
Saturday, November 1st, 2025
12:00 am EDT
Week 12Oklahoma vs
Alabama
Saturday, November 15th, 2025
12:00 am EST
Week 13Missouri vs
Oklahoma
Saturday, November 22nd, 2025
12:00 pm EST
Week 14LSU vs
Oklahoma
Saturday, November 29th, 2025
12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Missouri vs Oklahoma College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 22nd, 2025 at 12:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Missouri vs Oklahoma Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Missouri vs Oklahoma Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other November 22, 2025 NCAAFB Games

Odds Preview 7624