The Golden Eagles will play the Jaguars on Saturday, November 22nd, 2025. The matchup takes place at Hancock Whitney Stadium. Watch this exciting Week 13 matchup at 3:30 pm EST. Check local listings for coverage on ESPN+.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
| Bonus | |
|---|---|
 #1 BetMGMREVIEW | New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966 |
Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
We're now in the home stretch of the 2025 college football season, with Southern Miss and South Alabama meeting at Hancock Whitney Stadium for a key late-season matchup on Saturday, November 22nd, 2025. The playoffs are fast approaching, along with the annual Bowl games that kick off in December. Here's an overview of some important 2025 performance data for each team.
- SportsBetting3.com Power Rankings - As we wrap up the 2025 regular season, Southern Miss has notched a 99.33 Sun Belt Conference conference power ranking. On the other side of the gridiron, South Alabama has a 97.33 Sun Belt Conference power ranking.
- Away Southern Miss - Looking at Week 13, Southern Miss heads into this matchup with a 3-1 record as an away team. This ranks them 1st in the Sun Belt Conference for away team wins in 2025. Remember that a team's overall record and schedule strength will affect whether or not they make a December bowl game or qualify for the playoffs.
- Home South Alabama - Meanwhile, South Alabama has a 1-4 record as a home team for 2025. They currently rank 4th in the Sun Belt Conference for home team wins. Let's see if they can add another win to their record when they battle Southern Miss on Saturday, November 22nd, 2025.
- Points Scored - Now late in the 2025 season, Southern Miss ranks 2nd (305) in the Sun Belt Conference, with South Alabama currently ranking 4th (250) for points scored in the Sun Belt Conference.
- Points Against - Southern Miss currently stands 6th (259) in the Sun Belt Conference for points scored by opponents in the 2025 college football season. Their opponent, South Alabama, ranks 4th (281) in the Sun Belt Conference for points against them as the 2025 college football season comes to a close.
- Team Records - As we head into Week 13, Southern Miss has a 7-3 overall record for the 2025 regular season, with South Alabama possessing a 3-7 standing for the 2025 college football season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Top o' the mornin' to ya, laddies and lassies! Southern Miss is takin' on South Alabama!
This Week 13 showdown is happenin' at Hancock Whitney Stadium, where the crowd will go wild.
The Power Rankings favor Southern Miss with a 99.33 rank over South Alabama's 97.33.
Southern Miss is standin' strong with a 7-3 record, while South Alabama is strugglin' at 3-7.
We recommend BetRivers or BetMGM for a bet on this game. Review this game's prop bets. Compare the best point spread, total, and moneylines from our partner sportsbooks below.
Best Golden Eagles at Jaguars Odds
| Underdog South Alabama | Favorite Southern Miss |
|---|---|
| Over | Under |
|---|---|
| Underdog South Alabama | Favorite Southern Miss |
|---|---|
Matchup Odds FAQs
Southern Miss is a -1.5 -105 point spread favorite at BetMGM, while South Alabama is a +1.5 -115 point spread underdog at BetMGM.
The best over line is 53.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 53.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
Southern Miss is a -115 moneyline favorite at BetMGM and South Alabama is a -105 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
Southern Miss
South Alabama
11/22/25 3:30pm EST | -1.5 -105+1.5 -115 |
Underdog South Alabama - South Alabama bettors risk $100 to win $86.96 at -115 odds.
A +1.5 South Alabama underdog bet wins if they lose by 1, tie, or win outright. Your bet loses if they lose by 2 or more.
Favorite Southern Miss - Southern Miss bettors risk $100 to win $95.24 at -105 odds.
A -1.5 Southern Miss favorite bet wins if they win by 2 or more. Your bet loses if they win by 1, tie, or lose outright.
Southern Miss at South Alabama Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Southern Miss
South Alabama
No Touchdown
To Score 1st Touchdown
11/22/25 3:30pm EST | -130-110+10000Bet |
Southern Miss
South Alabama
Game to Overtime
11/22/25 3:30pm EST | Yes +1050No -10000Bet |
Southern Miss
South Alabama
Both Teams Score 10+
11/22/25 3:30pm EST | Yes -2000No +800Bet |
Southern Miss
South Alabama
Both Teams Score 20+
11/22/25 3:30pm EST | Yes -160No +125Bet |
| BetMGM | |
Southern Miss
South Alabama
Both Teams Score 30+
11/22/25 3:30pm EST | Yes +400No -625Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 13 | Southern Miss vs South Alabama Saturday, November 22nd, 2025 | USA 42, USM 35 Hancock Whitney Stadium | South Alabama by 7 |
| 2024 Week 13 | South Alabama vs Southern Miss Saturday, November 23rd, 2024 | USA 35, USM 14 M. M. Roberts Stadium | South Alabama by 21 |
| 2023 Week 8 | Southern Miss vs South Alabama Tuesday, October 17th, 2023 | USA 55, USM 3 Hancock Whitney Stadium | South Alabama by 52 |
| 2022 Week 12 | South Alabama vs Southern Miss Saturday, November 19th, 2022 | USA 27, USM 20 M. M. Roberts Stadium | South Alabama by 7 |
| 2021 Week 1 | Southern Miss vs South Alabama Saturday, September 4th, 2021 | USA 31, USM 7 Hancock Whitney Stadium | South Alabama by 24 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| Southern Miss | 5-3 | 0.625 | 7 | 5 | 358 | 329 | 4-3 | 3-2 | L3 |
| South Alabama | 3-5 | 0.375 | 4 | 8 | 318 | 365 | 2-4 | 2-4 | L1 |
Southern Miss & South Alabama Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Southern Miss Championship OddsNo NCAA College Football Championship TM Southern Miss YR: futures available
South Alabama Championship OddsNo NCAA College Football Championship TM South Alabama YR: futures available
Southern Miss & South Alabama Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Mississippi State vs Southern Miss | MSST 34, USM 17 Saturday, August 30th, 2025 |
| Week 2 | Jackson State vs Southern Miss | USM 38, JKST 20 Saturday, September 6th, 2025 |
| Week 3 | Appalachian State vs Southern Miss | USM 38, APP 22 Saturday, September 13th, 2025 |
| Week 4 | Southern Miss vs Louisiana Tech | LT 30, USM 20 Saturday, September 20th, 2025 |
| Week 5 | Jacksonville State vs Southern Miss | USM 42, JVST 25 Saturday, September 27th, 2025 |
| Week 7 | Southern Miss vs Georgia Southern | USM 38, GASO 35 Thursday, October 9th, 2025 |
| Week 8 | Southern Miss vs Louisiana | USM 22, UL 10 Saturday, October 18th, 2025 |
| Week 9 | Louisiana-Monroe vs Southern Miss | USM 49, ULM 21 Saturday, October 25th, 2025 |
| Week 11 | Southern Miss vs Arkansas State | USM 27, ARST 21 Saturday, November 8th, 2025 |
| Week 12 | Texas State vs Southern Miss | TXST 41, USM 14 Saturday, November 15th, 2025 |
| Week 13 | Southern Miss vs South Alabama | USA 42, USM 35 Saturday, November 22nd, 2025 |
| Week 14 | Troy vs Southern Miss | TROY 28, USM 18 Saturday, November 29th, 2025 |
| Bowls | Western Kentucky vs Southern Miss New Orleans Bowl | Tuesday, December 23rd, 2025 5:30 pm EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Morgan State vs South Alabama | USA 38, MORG 21 Saturday, August 30th, 2025 |
| Week 2 | Tulane vs South Alabama | TULN 33, USA 31 Saturday, September 6th, 2025 |
| Week 3 | South Alabama vs Auburn | AUB 31, USA 15 Saturday, September 13th, 2025 |
| Week 4 | Coastal Carolina vs South Alabama | CCU 38, USA 20 Saturday, September 20th, 2025 |
| Week 5 | South Alabama vs North Texas | UNT 36, USA 22 Saturday, September 27th, 2025 |
| Week 6 | South Alabama vs Troy | TROY 31, USA 24 (OT) Saturday, October 4th, 2025 |
| Week 8 | Arkansas State vs South Alabama | ARST 15, USA 14 Tuesday, October 14th, 2025 |
| Week 9 | South Alabama vs Georgia State | USA 38, GAST 31 Thursday, October 23rd, 2025 |
| Week 10 | Louisiana vs South Alabama | UL 31, USA 22 Saturday, November 1st, 2025 |
| Week 12 | South Alabama vs Louisiana-Monroe | USA 26, ULM 14 Saturday, November 15th, 2025 |
| Week 13 | Southern Miss vs South Alabama | USA 42, USM 35 Saturday, November 22nd, 2025 |
| Week 14 | South Alabama vs Texas State | TXST 49, USA 26 Saturday, November 29th, 2025 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Southern Miss vs South Alabama College Football Game
-
Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 22nd, 2025 at 3:30 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
-
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
-
Tap to the sportsbook's College Football page, look for the Southern Miss vs South Alabama Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Southern Miss vs South Alabama Game.
-
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other November 22, 2025 NCAAFB Games
- Wagner vs Long Island University
- Minnesota vs Northwestern
- Louisville vs SMU
- Harvard vs Yale
- Western Carolina vs VMI
- Bryant vs Stony Brook
- Kansas vs Iowa State
- Miami (FL) vs Virginia Tech
- Delaware vs Wake Forest
- North Carolina Central vs Morgan State
- Missouri vs Oklahoma
- Fordham vs Merrimack College
- Tulsa vs Army
- Rutgers vs Ohio State
- Dartmouth vs Brown
- Albany vs Monmouth
- Lehigh vs Lafayette
- Charlotte vs Georgia
- Baylor vs Arizona
- Washington State vs James Madison
- Old Dominion vs Georgia Southern
- Chattanooga vs Wofford
- Western Illinois vs Gardner-Webb
- Portland State vs Northern Colorado
- Ball State vs Toledo
- Nevada vs Wyoming
- Mercer vs Auburn
- Duquesne vs Robert Morris
- Missouri State vs Kennesaw State
- Eastern Illinois vs Alabama
- Lindenwood vs Southeast Missouri State
- Southern Utah vs North Alabama
- Youngstown State vs Northern Iowa
- Montana State vs Montana
- North Carolina A&T vs Elon
- Tennessee State vs Charleston Southern
- South Dakota State vs North Dakota
- Marshall vs Appalachian State
- Northern Arizona vs Weber State
- Sam Houston State vs Middle Tennessee
- New Mexico State vs UTEP
- Liberty vs Louisiana Tech
- Miss Valley State vs Prairie View A&M
- Incarnate Word vs Houston Christian
- Alabama A&M vs Texas Southern
- UConn vs Florida Atlantic
- South Florida vs UAB
- Michigan State vs Iowa
- Norfolk State vs Howard
- Duke vs North Carolina
- Kentucky vs Vanderbilt
- East Carolina vs UTSA
- Jacksonville State vs FIU
- Syracuse vs Notre Dame
- Arkansas vs Texas
- USC vs Oregon
- Tulane vs Temple
- Michigan vs Maryland
- TCU vs Houston
- Oklahoma State vs UCF
- Kansas State vs Utah
- Georgia State vs Troy
- Coastal Carolina vs South Carolina
- Furman vs Clemson
- Louisiana-Monroe vs Texas State
- New Mexico vs Air Force
- Pittsburgh vs Georgia Tech
- Colorado State vs Boise State
- Nebraska vs Penn State
- Tennessee vs Florida
- North Texas vs Rice
- California vs Stanford
- Illinois vs Wisconsin
- Western Kentucky vs LSU
- BYU vs Cincinnati
- Arizona State vs Colorado
- Washington vs UCLA
- Utah State vs Fresno State
- San Jose State vs San Diego State